Clear long-lasting moisturizing and whitening cosmetics and preparation method thereof

Abstract

The invention relates to the technical field of cosmetics, and provides clear long-lasting moisturizing and whitening cosmetics and a preparation method thereof. The cosmetics consist of moisturizing factor slow release microspheres, slow release hydrogels, hydrolyzed pearls, ceramide, glycerol, squalane, arbutin, nicotinamide, tea polyphenols, potassium sorbate, glyceryl stearate and water. The cosmetics have a good moisturizing effect and a good whitening effect, can realize long-lasting moisturizing, does not generate an oily feeling in a utilization process and brings a clear utilization feeling.

Description

technical field

[0001] The invention belongs to the technical field of cosmetics and provides a refreshing long-acting moisturizing and whitening cosmetic and a preparation method thereof. Background technique

[0002] Cosmetics refer to chemical industrial products or fine chemical products that are spread on any part of the human body surface by smearing, spraying or other similar methods to keep them in good condition. The development of the cosmetics industry has shifted from beauty as the main purpose to both beauty and skin care, and further developed to focus on scientific skin care while taking into account the effect of beauty. At present, moisturizing and whitening are important functions of cosmetics.

[0003] The main effect of whitening cosmetics is to reduce the production of melanin in the body. In the formation of melanin, ultraviolet radiation outside the body is an inducing factor, and tyrosine, tyrosinase (activity) and melanosomes are required in the bo...

Examples

Embodiment 1

[0032](1) Add 1 g of polylactic acid porous microspheres to 200 mL of phase-transition lysozyme solution, incubate in an incubator, rinse with HEPES buffer, and dry naturally to obtain phase-transition lysozyme-modified polylactic acid porous microspheres ; The incubation temperature is 20°C, the relative humidity is 70%, and the incubation time is 60 minutes;

[0033] The specific preparation process of polylactic acid porous microspheres is as follows: add 0.8g polylactic acid into 10mL dichloromethane, stir until completely dissolved, then add 12mL gelatin aqueous solution with a mass concentration of 5%, and perform rapid emulsification in a high-speed shear emulsifier , add the obtained emulsion into 30mL 2°C polyvinyl alcohol solution with a mass concentration of 0.05%, disperse the emulsion into small balls by magnetic stirring, then collect the small balls with 500mL 2°C polyvinyl alcohol solution, and store them in a fume hood Remove the solvent by volatilization, the...

Embodiment 2

[0039] (1) Add 1.2 g polylactic acid porous microspheres to 200 mL phase-transition lysozyme solution, incubate in an incubator, rinse with HEPES buffer, and dry naturally to obtain phase-transition lysozyme-modified polylactic acid porous microspheres. ball; the incubation temperature is 22°C, the relative humidity is 72%, and the time is 55min;

[0040] The specific preparation process of polylactic acid porous microspheres is as follows: add 0.8g polylactic acid into 10mL dichloromethane, stir until completely dissolved, then add 12mL gelatin aqueous solution with a mass concentration of 5%, and perform rapid emulsification in a high-speed shear emulsifier , add the obtained emulsion into 30mL 2°C polyvinyl alcohol solution with a mass concentration of 0.05%, disperse the emulsion into small balls by magnetic stirring, then collect the small balls with 500mL 2°C polyvinyl alcohol solution, and store them in a fume hood Remove the solvent by volatilization, then wash away th...

Embodiment 3

[0046] (1) Add 1.4 g of polylactic acid porous microspheres to 200 mL of phase-transition lysozyme solution, incubate in an incubator, rinse with HEPES buffer, and dry naturally to obtain phase-transition lysozyme-modified polylactic acid porous microspheres. ball; the incubation temperature is 24°C, the relative humidity is 74%, and the time is 52min;

[0047] The specific preparation process of polylactic acid porous microspheres is as follows: add 0.8g polylactic acid into 10mL dichloromethane, stir until completely dissolved, then add 12mL gelatin aqueous solution with a mass concentration of 5%, and perform rapid emulsification in a high-speed shear emulsifier , add the obtained emulsion into 30mL 2°C polyvinyl alcohol solution with a mass concentration of 0.05%, disperse the emulsion into small balls by magnetic stirring, then collect the small balls with 500mL 2°C polyvinyl alcohol solution, and store them in a fume hood Remove the solvent by volatilization, then wash a...

technical field

[0001] The invention belongs to the technical field of cosmetics and provides a refreshing long-acting moisturizing and whitening cosmetic and a preparation method thereof. Background technique

[0002] Cosmetics refer to chemical industrial products or fine chemical products that are spread on any part of the human body surface by smearing, spraying or other similar methods to keep them in good condition. The development of the cosmetics industry has shifted from beauty as the main purpose to both beauty and skin care, and further developed to focus on scientific skin care while taking into account the effect of beauty. At present, moisturizing and whitening are important functions of cosmetics.

[0003] The main effect of whitening cosmetics is to reduce the production of melanin in the body. In the formation of melanin, ultraviolet radiation outside the body is an inducing factor, and tyrosine, tyrosinase (activity) and melanosomes are required in the bo...

Examples

Embodiment 1

[0032](1) Add 1 g of polylactic acid porous microspheres to 200 mL of phase-transition lysozyme solution, incubate in an incubator, rinse with HEPES buffer, and dry naturally to obtain phase-transition lysozyme-modified polylactic acid porous microspheres ; The incubation temperature is 20°C, the relative humidity is 70%, and the incubation time is 60 minutes;

[0033] The specific preparation process of polylactic acid porous microspheres is as follows: add 0.8g polylactic acid into 10mL dichloromethane, stir until completely dissolved, then add 12mL gelatin aqueous solution with a mass concentration of 5%, and perform rapid emulsification in a high-speed shear emulsifier , add the obtained emulsion into 30mL 2°C polyvinyl alcohol solution with a mass concentration of 0.05%, disperse the emulsion into small balls by magnetic stirring, then collect the small balls with 500mL 2°C polyvinyl alcohol solution, and store them in a fume hood Remove the solvent by volatilization, the...

Embodiment 2

[0039] (1) Add 1.2 g polylactic acid porous microspheres to 200 mL phase-transition lysozyme solution, incubate in an incubator, rinse with HEPES buffer, and dry naturally to obtain phase-transition lysozyme-modified polylactic acid porous microspheres. ball; the incubation temperature is 22°C, the relative humidity is 72%, and the time is 55min;

[0040] The specific preparation process of polylactic acid porous microspheres is as follows: add 0.8g polylactic acid into 10mL dichloromethane, stir until completely dissolved, then add 12mL gelatin aqueous solution with a mass concentration of 5%, and perform rapid emulsification in a high-speed shear emulsifier , add the obtained emulsion into 30mL 2°C polyvinyl alcohol solution with a mass concentration of 0.05%, disperse the emulsion into small balls by magnetic stirring, then collect the small balls with 500mL 2°C polyvinyl alcohol solution, and store them in a fume hood Remove the solvent by volatilization, then wash away th...

Embodiment 3

[0046] (1) Add 1.4 g of polylactic acid porous microspheres to 200 mL of phase-transition lysozyme solution, incubate in an incubator, rinse with HEPES buffer, and dry naturally to obtain phase-transition lysozyme-modified polylactic acid porous microspheres. ball; the incubation temperature is 24°C, the relative humidity is 74%, and the time is 52min;

[0047] The specific preparation process of polylactic acid porous microspheres is as follows: add 0.8g polylactic acid into 10mL dichloromethane, stir until completely dissolved, then add 12mL gelatin aqueous solution with a mass concentration of 5%, and perform rapid emulsification in a high-speed shear emulsifier , add the obtained emulsion into 30mL 2°C polyvinyl alcohol solution with a mass concentration of 0.05%, disperse the emulsion into small balls by magnetic stirring, then collect the small balls with 500mL 2°C polyvinyl alcohol solution, and store them in a fume hood Remove the solvent by volatilization, then wash a...

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