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Ingestible formulation

A technology of emulsion and thickener, applied in the packaging field of producing the emulsion of the present invention, storing and transporting the emulsion until the mixture is administered, can solve the incompatibility of non-polar carriers, vehicles and/or solvents, difficulties in realization, unresolved problems Provide specific examples, etc.

Pending Publication Date: 2021-05-25
昆泰克有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, neither WO2007 / 142542 nor WO2017 / 183996 provide specific examples of ingestible formulations of those milk ingredients
[0013] Although it is possible to formulate the milk components described in WO2007 / 142542 or WO2017 / 183996 for enteral administration, there are certain difficulties
Milk components described in WO2007 / 142542 or WO2017 / 183996 are capable of dispersing and / or dissolving in water, but they are not compatible with non-polar carriers, vehicles and / or solvents

Method used

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  • Ingestible formulation
  • Ingestible formulation
  • Ingestible formulation

Examples

Experimental program
Comparison scheme
Effect test

preparation example

[0383] base mix

[0384] Element ％ gram water 50.77 178.3 glycerin 48.24 169.4 Guar Gum 0.38 1.30 xanthan gum 0.28 1.00 carrageenan 0.27 1.00 Potassium sorbate 0.06 0.20 Total: 100.0 351.2

[0385] emulsion preparation

[0386] Element ％ gram Linseed oil 60.75 607.5 "Basic Mixture" 35.12 351.2 Monk Fruit Concentrate 2.72 27.2 cationic fraction 1.25 12.5 ascorbic acid 0.1 1.0 strawberry flavoring 0.06 0.6 Total: 100.0 1000.0

[0387] Example recipe method:

[0388] Emulsions consist of four stages of preparation:

[0389] Part 1 - Aqueous solution of cationic fraction;

[0390] · Part 2 – Base Mixture;

[0391] · Part 3 – Oils and base mixes; and

[0392] • Part 4 - Final Emulsion.

[0393] Part 1 – Cationic fraction in water:

[0394] 1. Dissolve the cationic part with 15% water. Leave for at least 3 hours to fully hydrate and dissolve, ma...

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Abstract

The invention relates to an emulsion of an oil and at least one bioactive protein and / or at least one bioactive peptide. The bioactive protein / peptide is typically extracted from milk, and the oil is typically an edible oil. The invention also relates to a method of producing the emulsion of the invention. The invention also relates to packaging suitable for storing and transporting the emulsion until the mixture is administered. Conveniently the packaging allows the emulsion to be provided in single use, pre-dosed, ready-to-use form. Advantageously the emulsion is both stable and allows for the substantial retention of the activity of the bioactive protein / peptide.

Description

technical field [0001] The present invention relates to the following emulsions: [0002] i) at least one biologically active protein and / or at least one biologically active peptide; and [0003] ii) Oil. [0004] In particular embodiments, the present invention relates to emulsions of: [0005] i) at least one biologically active protein and / or at least one biologically active peptide; and [0006] ii) Edible oils, such as oils containing omega-3 fatty acids, such as flaxseed oil. [0007] In another particular embodiment, the invention relates to an emulsion of two or more milk proteins extracted from milk and an edible oil, such as an oil comprising omega-3 fatty acids, such as linseed oil. [0008] The invention also relates to methods of producing the emulsions of the invention. [0009] The invention also relates to packaging suitable for storing and transporting the emulsion until administration of the mixture. Conveniently, the packaging allows the emulsion to be...

Claims

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Application Information

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IPC IPC(8): A61K38/40A61K38/44A61K39/395A61K38/47A61K38/54A61K38/46A61K38/17A61K38/18A61K36/55A61K9/107A61K47/44A61K47/36A61P9/00A61P33/02A61P31/04A61P31/10A61P35/00A61P19/02A61P9/10A23L33/19A23L33/12
CPCA61K38/40A61K39/39508A61K38/47A61K38/1729A61K38/465A61K36/55A61K9/107A61K47/44A61P31/04A61P31/10A61P33/02A61P9/00A61P19/02A61P35/00A61K38/443A23L33/19A23J1/20A23D7/0053A61K2300/00A23V2002/00A23V2250/5424A23V2250/54248A23V2250/5425A23V2300/30A23V2250/154A23V2250/6406A23V2250/506A23V2250/5086A23V2250/5036A23V2250/054A23V2250/1874A23V2250/1886A23V2250/188A23V2250/24A23V2250/708A23V2250/21A23V2200/30A23L33/18A23L33/17A61K47/36A61K36/185A23L33/115A23L29/269A23L29/256A23L29/238C12Y111/01007A61K38/54A61K38/1774A61K38/1891A61K31/375
Inventor R·克莱康伯C·艾弗里E·颜D·罗特
Owner 昆泰克有限公司
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