Spatial memory behavior training system guided by visual information

Abstract

The invention provides a spatial memory behavior training system guided by visual information. The spatial memory behavior training system comprises a maze, a rotatable bracket fixedly connected with the maze, and an animal behavior analysis device which is used for main control and data acquisition and analysis and comprises a controller, an industrial camera, a first feeder, a second feeder and a third feeder, the maze comprises a square box body, two bosses, a starting arm, a first decision arm, a second decision arm, a first return arm, a second return arm and five lifting type automatic doors, wherein the square box body is composed of a bottom plate, a display and three frame plates, the upper end of the square box body is open, the two bosses are arranged in the square box body, the starting arm is composed of the two bosses and the square box body, and the lifting type automatic doors are arranged in the five arms respectively; and an experimental animal starting point area, a decision area and a reward area are arranged in the maze, and the starting arm, the first decision arm and the second decision arm present different visual prompts during an experiment. When the system is used, space information and visual information can be effectively separated in animal space guiding, interference of human factors is reduced to the maximum extent, and excessive extra interference information caused by back-and-forth movement of animals is reduced.

Description

technical field [0001] The invention relates to an animal space memory behavior training device, in particular to a visual information-guided space memory behavior training system. Background technique [0002] Spatial cognition plays an important role in human daily life, such as finding routes, locating places and targets, using maps for navigation, etc. It is a necessary condition for independent activities in the environment. Many mental illnesses are accompanied by a decline in spatial cognition, such as schizophrenia, Alzheimer's syndrome, and Parkinson's syndrome. Therefore, it is very important to study the basic research of spatial guidance function based on rodents. The spatial memory function of rodents is one of its important cognitive functions and can be scientifically and quantitatively measured, so it is often used as an entry point for basic research. At present, this kind of research mainly uses hardware devices designed according to the theoretical parad...

AI Technical Summary

Problems solved by technology

[0003] Currently common animal spatial memory behavior training devices are either designed based on a single visual-dependent oriented paradigm, or are designed based on a single spatially dependent oriented paradigm (such as the training device disclosed in Chinese patent literature with publication number CN111685049A), which The common problems are as follows: First, two sets of devices are required to train the spatial memory behavior of animals in the visual-dependent paradigm and the spatial-dependent paradigm respectively, which increases the cost of the equipment, the experimental operation is troublesome, and it is not conducive to the spatial memory oriented to the visual information of the animal. Further research on the neural mechanism; second, due to the limited structure of the existing training device, there are many human interference factors during the experiment, and generally the animal needs to return to the starting point in the same way, adding too much additional interference information to the mouse, Thus affecting the training success rate and training efficiency

Images