Detection system for urinary system infection pathogens and kit and application thereof

A urinary system infection and pathogen detection technology, applied in the biological field, can solve the problems of high drug resistance rate of strains, incomplete coverage, and increased medical burden on patients, so as to ensure specificity and sensitivity, ensure accuracy and reliability, and reduce medical costs. cost effect
CN112852984APending Publication Date: 2021-05-28HUADONG HOSPITAL +1
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
HUADONG HOSPITAL
Publication Date
2021-05-28

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Abstract

The invention relates to a urinary system infection pathogen detection system and a kit and application thereof, the detection system comprises 20 pairs of primers, including 18 pairs of detection primers, one pair of human DNA internal reference primers and one pair of system quality control internal reference primers. According to the detection system for the drug-resistant gene of the urinary system infection pathogen as well as the kit and the application of the detection system, conventional detection is not needed, and synchronous identification and quantitative analysis of various pathogens can be directly carried out on a urine sample in the same reaction system. The system has the advantages of strong specificity, high sensitivity, good repeatability, rapidness and accuracy, provides comprehensive, accurate and low-cost etiological diagnosis for clinic in the first time, and provides important reference for individualized medication and precise medical treatment.
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Description

technical field

[0001] The invention relates to a multiple gene detection product and a detection system used in the product, belonging to the field of biotechnology. Background technique

[0002] Urinary system infection, also known as urinary tract infection (Urinary Tract Infections, UTI), is one of the most common infectious diseases clinically. A variety of pathogens can invade the urinary system and grow and reproduce in large numbers, causing clinical symptoms such as frequent urination, urgency, dysuria, dysuria, and waist and leg pain. In severe cases, severe diseases such as sepsis and acute and chronic renal dysfunction may develop; However, urogenous sepsis and septic shock progress very rapidly, and the fatality rate is as high as 28.3% to 41.1%. UTI accounts for about 40% of nosocomial infections in foreign countries, ranking first; while the incidence of UTI in my country is as high as 20.8% to 31.7%, second only to respiratory tract infections, and more than...

Claims

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