Transdermal diffusion cell, transdermal diffusion instrument and oral mucosa transdermal diffusion experiment method

Abstract

The invention discloses a transdermal diffusion cell, a transdermal diffusion instrument and an oral mucosa transdermal diffusion experiment method, and belongs to the technical field of transdermal experiments. A stirring device is arranged at the upper end of a dosing cell of the diffusion cell and comprises a base, a first power source, a first transmission unit, a second transmission unit, a lifting table, a stirring unit and a control module. The second transmission unit comprises a driving gear and at least two driven gears which are arranged on the periphery of the driving gear in a surrounding mode and engaged with the driving gear, and lead screws are arranged on the driven gears and can drive the lifting table to move up and down; the stirring unit comprises a second power source and a stirring rod, and a stirring paddle located in the dosing pool is arranged at one end of the stirring rod. According to the invention, the environment in the diffusion cell is close to the environment in the oral cavity during gargling through stirring, so that the oral mucosa transdermal diffusion experiment is effectively carried out, the experiment result is more accurate, and the invention further provides a transdermal diffusion instrument and an oral mucosa transdermal diffusion experiment method.

Description

technical field [0001] The invention belongs to the technical field of transdermal experiments, and in particular relates to a transdermal diffusion cell, a transdermal diffusion instrument and an oral mucosa transdermal diffusion experimental method. Background technique [0002] The purpose of the experiment of the transdermal diffusion device is to study the rate of drug penetration through the skin. The experimental method is to clamp the skin to be tested in the diffusion cell, then place the diffusion cell in the transdermal diffusion device, and heat the diffusion cell. The method is to make the drug to be tested on the upper side of the skin penetrate the skin of the diffusion cell and infiltrate into the physiological saline on the lower side of the skin. The concentration in the solvent is detected through regular extraction, and the amount of drug permeated through the skin is analyzed, and the experimental data is recorded. Finally, The average data was obtained ...

AI Technical Summary

Problems solved by technology

[0004] Technical problem: The present invention aims at the problem that the existing transdermal diffusion cell is difficult to effectively simulate the transdermal diffusion process of the oral mucosa when gargling, and provides a transdermal diffusion cell. Using this diffusion cell, it can be closer to the process of rinsing the mouth. Oral environment, so as to more accurately simulate the transdermal diffusion process of the oral mucosa during the mouthwash process; further, provide a transdermal device that can more accurately simulate the transdermal diffusion process of the oral mucosa during the mouthwash process Diffusion instrument; in addition, an oral mucosa transdermal diffusion test method is provided to simulate the oral mucosa transdermal diffusion process during mouthwash

Images