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Novel pathological sealing sheet material

A sheet material and pathological technology, applied in the preparation and coating of test samples, can solve the problems of ultraviolet pollution, inconvenient use, etc., and achieve the effect of simple ingredients, low toxicity and good effect

Active Publication Date: 2021-06-18
SHANDONG JUNTENG MEDICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the patent (CN 108225871 A), UV optical glue is used to replace traditional neutral gum, which can be quickly cured within a few minutes, greatly shortening the drying time of slices, but because UV optical glue needs to be activated under the irradiation of ultraviolet lamps, it needs Special drying equipment, inconvenient to use and has the problem of ultraviolet pollution

Method used

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  • Novel pathological sealing sheet material
  • Novel pathological sealing sheet material
  • Novel pathological sealing sheet material

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Experimental program
Comparison scheme
Effect test

Embodiment 1-9

[0054] The preparation method of embodiment 1-9 is:

[0055] Step 1: Prepare the light-transmitting polymer into a thin film with a thickness of 110 μm to obtain a light-transmitting polymer substrate;

[0056] Step 2: According to 0.5g / m on the side with light-transmitting polymer substrate 2 Apply the coating agent according to the dosage and dry;

[0057] Step 3: Apply 10g / m on the other side of the light-transmitting polymer substrate 2 Apply the optical pressure-sensitive adhesive in the amount of the adhesive, dry;

[0058] Step 4: Apply 22g / m on the outer side of the pressure-sensitive adhesive layer 2 Apply the polymer composed of acrylate and / or methacrylate in the amount of , dry;

[0059] Step 5: Cut the material dried in step 4 into strips with a width of 24mm and a length of 80m and roll them up for placement. When rolled up, the protective coating is on the outside and the polymer layer is inside.

[0060] The proportions of isobornyl methacrylate and n-buty...

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Abstract

A novel pathological sealing sheet material comprises a sealing sheet material, and the sealing sheet material sequentially comprises a polymer layer composed of acrylics and / or class A acrylics, a pressure-sensitive adhesive layer, a light-transmitting polymer base material and a protective coating from bottom to top. The pathological sealing sheet material is simple in component, good in effect, low in toxicity and novel, is mainly used for sealing sheet after pathological tissue dyeing, has transparency and refractive index similar to those of a glass slide, has rapid interaction with an activating solvent, the sealing sheet material has compatibility with dyeing chemicals used on a sample, and when the sealing sheet material is used on a microscope glass slide, preferably, the sealing sheet material can be exposed to high humidity and high temperature for a long time, but the sealing sheet material cannot be obviously separated from the glass slide, and the dyed pathological sample does not obviously fade.

Description

technical field [0001] The invention belongs to the field of pathological tissue slice fixation, in particular to a novel pathological sealing material. Background technique [0002] In life disciplines such as histopathology and microbiology, specimens are often examined using microscopy (eg, light microscopy), a method that requires the specimen to be placed on a glass slide, stained, and then examined using a glass coverslip with adhesive cover sheet. Neutral gums are often used as adhesives in pathological examinations. After the coverslipping is completed, the neutral resin used will take 4-7 days to bond the coverslip and slide well under natural conditions, and it will not be dry after 1-2 months in a ventilated place. The smell of xylene. Until it is completely dry, the pathological slides are not suitable for full digital scanning (easily slip or card) or storage (easily stick to other slides). If a new method of coverslipping could be developed that shortens dr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N1/30G01N1/28C08J7/043C08J7/04C08L1/12
CPCG01N1/28G01N1/30C08J7/042C08J7/043C08J2301/12C08J2433/10C08J2483/04
Inventor 郭玉川夏国建孙玉芬王文杰
Owner SHANDONG JUNTENG MEDICAL TECH CO LTD
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