Multichannel wireless heredity photostimulation system and method

Abstract

The invention provides a multichannel wireless heredity photostimulation system and method. The system comprises an upper computer, a photostimulator and an array type stimulating light pole, wherein the photostimulator comprises a plurality of stimulating channels, different stimulating channels electrically communicate with different zones of the array type stimulating light pole, the upper computer is used for setting photostimulation parameters, the photostimulation parameters comprise frequency of pulses, duty ratio, stimulation time and one or more stimulating channels, the upper computer is in wireless connection with the photostimulator, and the photostimulator is used for receiving the photostimulation parameters set by the upper computer and outputting electric pulse signals to zones of the array type stimulating light pole electrically communicating with the stimulating channels in the photostimulation parameters. According to the method and the system, stimulated zones can be independently selected.

Description

technical field [0001] The present invention relates to the technical field of optical stimulation, and more specifically, to a multi-channel wireless optogenetic stimulation system and method. Background technique [0002] Optogenetic technology is a new technology combining optics and genetics, which can accurately regulate the activity of specific neurons by means of light control. By using viral vectors to introduce light-sensitive proteins into specific cells for expression, the introduced light-sensitive proteins can only be activated by light of specific wavelengths, so light of corresponding wavelengths can be used to activate or inhibit ion channels to achieve precise regulation of nerve cell functions. The time accuracy can reach the range of milliseconds, and the precise control of a single cell or even a subcellular range can be realized spatially. In recent years, this technique has become very popular in neuroscience research and will lead to the next generati...

AI Technical Summary

Problems solved by technology

The regulation of the optical stimulator depends on the wired connection, and there are few parameters for regulation, and the stimulated area cannot be independently selected.

Due to the relatively high power of the device, long-term use will cause the device to heat up, which will affect the activity of nerve cells and is not conducive to the growth of nerve cells

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