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8 results about "Optode" patented technology

An optode or optrode is an optical sensor device that optically measures a specific substance usually with the aid of a chemical transducer.

In-situ chemical imaging method and system applied to soil drilosphere

An in-situ chemical imaging method and system applied to a soil drilosphere. The method comprises: S1, preparing an earthworm burrowing box and filling same with soil; S2, selecting appropriate earthworms and placing same in the soil for culturing, such that sufficient earthworm pores are generated in the soil; S3, sequentially providing a filter membrane (9), a DGT adsorption membrane (107) and a pH planar optode membrane (106) on a soil profile of a drilosphere which needs to be imaged, such that the three membranes can all be fully attached to the soil profile of the drilosphere, applying ultraviolet light under dark conditions, culturing for a period of time, and capturing a fluorescence signal emitted by the pH planar optode membrane (106), so as to obtain a pH fluorescence image; S4, performing color development on the DGT adsorption membrane (107); and S5, capturing a color-developed image of the DGT adsorption membrane (107) to obtain a DGT image, and performing picture processing on the DGT image and the pH fluorescence image to obtain spatial distribution images of available phosphorus and pH in the drilosphere. The problem of difficulty in in-situ detection of a biogeochemical cycling process driven by earthworm activities in soil is solved.
Owner:ZHEJIANG UNIV

Hydrocarbon enhanced ionophore-based ion-selective optodes

Hydrocarbon enhanced ionophore-based ion-selective optodes (ISOs) and methods of their use are provided. The ISOs exhibit improved ultrasensitive ion sensing due to the addition of ultralow-polarity hydrocarbons to the sensing phase using specific ratios of sensing phase components. The ISOs can be operated under an exhaustive or non-exhaustive extraction response mode.
Owner:VIRGINIA COMMONWEALTH UNIV

Method for determining the lithium content in a biological fluid

Method for determining an amount of lithium contained in a biological fluid, said method comprising the steps consisting in adding, to a biological fluid sample of known volume, a given volume of a discriminating solution, the effect of which is to obtain a biological fluid solution buffered at a pH of between 6 and 8 and to bring about precipitation of at least a portion of the cations contained in the biological fluid sample except for the lithium ions. The method further comprises the steps consisting in depositing a given volume of biological fluid solution on an active layer (2) of an optode (1), said active layer comprising a chemical transducer of which at least one optical property is modified in the presence of lithium ions in the biological fluid solution, in measuring at least one characteristic of at least one light wave emitted or reflected by the active layer of the optode and in determining, from the at least one measured characteristic and from calibration data, an amount of lithium contained in the biological fluid.
Owner:CENT NAT DE LA RECH SCI (C N R S) +3

Monitoring device

A monitoring device (1) comprises a microwell plate (10) comprising microwells (20) dimensioned to hold a respective biological entity and a channel plate (30) comprising at least one fluid channel (40, 42) in fluid connection with a fluid input port (11; 11A, 11B) and a fluid output port (13; 13A, 13B). An optode composition (25) is present in the microwells (20) and comprising an analyte-sensitive optode compound generating a detectable optical signal in response to an analyte. The channel plate (30) and the microwell plate (10) are slidably arranged together and movable relative to each other between a loading position, in which the at least one fluid channel (40, 42) is in fluid connection with at least a subset (21, 23) of the plurality of microwells (25), and a monitoring position, in which the channel plate (30) closes the at least a subset (21, 23) of the plurality of microwells (20).
Owner:TENJE MARIA +1

Brain magnetic compatible near-infrared channel arrangement and modulation frequency distribution method

PendingCN121562123ADiagnostics using spectroscopySensorsFunctional imagingOptode
The invention discloses a brain magnetic compatible near-infrared channel arrangement and modulation frequency distribution method, and belongs to the technical field of multi-mode brain function imaging. In order to solve the problems that in the prior art, personalized optrode arrangement optimization is difficult, standardized meta-information files are tedious to generate, and brain magnetic compatible frequency distribution efficiency is low, optrode coordinates are constructed based on individual head three-dimensional information, the positions of a light source and a detector are optimized through a greedy algorithm, and optrode two-dimensional coordinates are adjusted through dimension reduction and nonlinear optimization; and an automatic scheme is generated by using a method for carrying out brain magnetic compatible frequency allocation by using a graph coloring algorithm. According to the method, the experimental channel scheme of the whole brain or the region of interest can be quickly generated, the standard file and the channel visualization graph can be automatically generated, the brain magnetic compatibility and the high frequency utilization rate are considered at the same time, and the method is suitable for multi-mode brain imaging experiment preparation and personalized helmet or flexible cap optrode design.
Owner:PEKING UNIV

A new-born brain function evaluation and neurodevelopment prognosis prediction system

PendingCN122460883ARealize complementary advantagesIncreased sensitivityFeature vectorMedicine
The application discloses a new-born brain function evaluation and neural development prognosis prediction system, relates to the technical field of new-born brain function evaluation, and comprises an EEG electrode module, an fNIRS optical electrode module and a prediction module. The EEG electrode module is used for collecting EEG signals of a new-born in real time within a set time period. The fNIRS optical electrode module is used for collecting rSO2 signals of the new-born in real time within the set time period. The prediction module is used for performing signal preprocessing on EEG signals of the whole brain of the new-born and the rSO2 signals of the new-born, obtaining preprocessed EEG signals and preprocessed rSO2 signals, generating a dynamic brain function connection network sequence capable of representing the time evolution characteristics of brain function connection structures by using the preprocessed EEG signals and the preprocessed rSO2 signals, obtaining a time-varying feature vector by using the dynamic brain function connection network sequence, and obtaining a prediction result of new-born brain function evaluation and neural development prognosis based on the time-varying feature vector and a prediction model established in advance.
Owner:PEKING UNIVERSITY FIRST HOSPITAL (PEKING UNIVERSITY FIRST CLINICAL MEDICAL COLLEGE) +1

A method and system for calculating cerebral blood flow based on time-frequency near-infrared brain imaging

This invention discloses a method and system for calculating brain region blood flow based on time-frequency near-infrared brain imaging, belonging to the field of healthcare informatics technology. It converts light intensity data obtained from time-frequency near-infrared brain imaging into electrical data, and calculates and post-processes the electrical data using a modified Lambert-Beer law to generate a relative blood flow distribution chromatogram of the brain region under test. Simultaneously with the calculation and generation of the relative blood flow distribution chromatogram, a mental health assessment is conducted on the subject, and the relative blood flow distribution chromatogram is used to assist in evaluating the subject's mental health assessment results. This invention employs a novel multi-ring regular hexagonal honeycomb mesh structure construction method and sets a corresponding optical pole arrangement, significantly increasing the number of effective channels for calculation per unit area. Based on the modified Lambert-Beer law, it considers individual influencing factors, making the information expressed by the generated relative blood flow distribution chromatogram more accurate and comprehensive.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY