Unlock instant, AI-driven research and patent intelligence for your innovation.

Antibacterial mouthwash and preparation method thereof

A technology of mouthwash and deionized water, which can be used in oral care, antibacterial drugs, and pharmaceutical formulations. It can solve problems such as easy deposition of tooth stains on the surface of teeth, doubts about oral safety, and unsuitability for long-term use. The effect of time, high safety, and strong foaming power

Active Publication Date: 2021-08-03
浙江吉叶生物科技有限公司
View PDF9 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The bacteriostasis of general existing mouthwash is mainly realized by chemically synthesized bacteriostat, for example with triclosan, chlorhexidine gluconate etc. Safety has been controversial in recent years; and if chlorhexidine gluconate is used for a long time, it will easily deposit stains on the tooth surface, affect the sense of taste and cause recurrent aphthous ulcers
In addition, what is more serious is that long-term use of mouthwash containing chemical antibacterial agents can easily lead to imbalance of normal bacterial flora in the oral cavity, so it is not suitable for long-term use
[0004] At the same time, the surfactants added in existing mouthwashes are mostly selected from monoglycerides, acetylated monoglycerides, sorbitan esters or sodium stearyl lactate, and the safety of long-term oral use has been questioned

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0078] The preparation process of Changyao Babao extract is as follows: Weigh 100g of fresh stems and leaves of Changyao Babao, crush and grind them in a mortar, add pure water according to the liquid-solid ratio of 6:1, shake well, seal, and place in a dark room place, soaked for 12 hours, and ultrasonicated for 5 minutes every 4 hours during the period, a total of 3 times, the obtained leachate was mixed, recovered and filtered under reduced pressure to obtain the Changyao Babao extract, and the finished product had a faint green color.

[0079] After multiple process verifications, the optimal process parameters of the mouthwash of the present invention are: 8% of Changyao Babao extract, 0.2% of bellflower juice, 3% of humectant, 0.05% of antiseptic, 0.2% of mineral salt, natural surface active Agent 11%, the balance is deionized water.

[0080] The optimum process conditions for the preparation of natural surfactants are as follows:

[0081] (1) After the Eucommia leaves ...

Embodiment 1

[0087] In the present embodiment, the formula of mouthwash is: 5% of Changyao Babao extract, 0.1-0.5% of bellflower juice, 3% of humectant, 0.01% of antiseptic, 0.1% of mineral salt, 2% of natural surfactant, The balance is deionized water.

Embodiment 2

[0089] In the present embodiment, the formula of mouthwash is: 10% of Changyao Babao extract, 0.5% of bellflower juice, 5% of humectant, 0.1% of preservative, 0.5% of mineral salt, 20% of natural surfactant, and the balance for deionized water.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides antibacterial mouthwash and a preparation method thereof, and the antibacterial mouthwash comprises the following components in percentage by weight: 5-10% of Hylotelephium spectabile extracting solution, 0.1-0.5% of platycodon grandiflorum juice, 3-5% of a humectant, 0.01-0.1% of a preservative, 0.1-0.5% of mineral salt, 2-20% of a natural surfactant and the balance of deionized water. According to the invention, the Hylotelephium spectabile extracting solution is innovatively used as a main component for sterilizing and diminishing inflammation in the mouthwash, so that the mouthwash has the effects of sterilizing and diminishing inflammation, is safe and harmless, and can be used for a long time. Compared with a chemical surfactant, a natural surfactant is selected, so that the safety is higher, and the antibacterial mouthwash is more suitable for consumption fields.

Description

technical field [0001] The invention relates to the technical field of medical oral care, relates to daily chemical products, in particular to an antibacterial mouthwash and a preparation method thereof. Background technique [0002] At present, the main components of mouthwash are essence, surfactant, fluoride, strontium chloride, alcohol and water, etc., which can clean the oral cavity and prevent dental caries and periodontitis. [0003] The bacteriostasis of general existing mouthwash is mainly realized by chemically synthesized bacteriostat, for example with triclosan, chlorhexidine gluconate etc. Safety has been controversial in recent years; and if chlorhexidine gluconate is used for a long time, tooth stains will be easily deposited on the tooth surface, which will affect the sense of taste and cause recurrent aphthous ulcers. In addition, what is more serious is that long-term use of mouthwash containing chemical antibacterial agents can easily lead to imbalance of...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61Q11/00A61P1/02A61P31/02A61P31/04
CPCA61K8/9789A61Q11/00A61P1/02A61P31/02A61P31/04A61K2800/82A61K2800/596A61K2800/5922
Inventor 余江华叶章颖赵海凤
Owner 浙江吉叶生物科技有限公司