34results about How to "Preserve efficacy" patented technology

An implantable medical apparatus includes a structure formed from bioabsorbable polymers. The apparatus also contains a therapeutic agent dispersed throughout the structure or coated on the structure in such a manner as to elute the therapeutic agent when implanted in an anatomical conduit. The apparatus can be constructed from a blend of polymers and other agents. The apparatus is implanted into the conduit by expansion with a balloon or some other expandable means. The morphology or arrangement of the polymeric structure ensures that the device maintains its shape characteristics to ensure proper modeling of the vessel. In particular, the crystallinity of the polymeric structure is adjusted so as to resist recoil.

A polymeric medical device is constructed from bioabsorbable polymers. The device is constructed from a tube comprised of at least one polymer. The polymer is treated at pre-determined heating and cooling temperatures to obtain a desired morphology. The morphology or arrangement of the polymeric structure ensures that the device maintains its shape characteristics to ensure proper modeling of the vessel. In particular, the crystallinity of the polymeric structure is adjusted so as to resist recoil. The device can also contain a therapeutic agent dispersed throughout the structure or coated on the structure in such a manner as to elute the therapeutic agent when implanted in an anatomical conduit. The device can also be constructed from a blend of polymers and other agents such as plasticizers.

The invention discloses a preparing method for pomelo wine. According to the method, water, sugar, honey, acid, pectinase, yeast cell wall, nutrimental agents and yeast are added into a crushed pomelo and mixed uniformly to be fermented at the temperature of about 18 DEG C, an odor absorber is added when the alcoholic strength is about 6% vol, after fermentation is finished, wine liquid is taken and stored in the environment with the temperature of about 2 DEG C, wine sediment is removed after 60 days, then the wine liquid is stored for about 90 days, then the wine liquid is placed in the environment with the temperature of about minus 4 DEG C for 3 days, clarification is carried out, and the wine liquid is filtered and sterilized after being placed in the environment with the temperature of about minus 4 DEG C for 4 days. According to the method, the skin can also be fermented for generating the pomelo wine, the inhibiting effect on the fermenting effect from special ingredients in the pomelo skin is overcome, and the pomelo wine with the special taste can be brewed, and has the dense lemon scent; the way of adding the odor absorber to the special fermenting process is fished out, bitterness of the pomelo can be covered up, flavor compounds in the pomelo wine are effectively preserved, the scent of the pomelo wine is more complex, and the mouthfeel is enhanced.

Pharmaceutical compositions having at least one crystal protein and a nicotinic acetylcholine receptor agonist in amounts effective to inhibit a parasitic worm or helminth infection in a vertebrate or mammal are described. Methods for treating a parasitic worm or helminth infection in a subject are also described. The methods include administering to the subject a therapeutically effective amount of the at least one crystal protein and a nicotinic acetylcholine receptor agonist. The crystal proteins can be isolated from Bacillus thuringiensis and include Cry5B, Cry21, Cry14A, Cry6A, and Cry13A. The nicotinic acetylcholine receptor agonist can be from the levamisole family, which include levamisole, pyrantel, and tribendimidine.

Conjugating LHRH to curcumin (LHRH-Curcumin) substantially enhances the bioavailability of curcumin, targets it to cells expressing LHRH receptors, facilitates intravenous administration, and increases the anti-cancer efficacy of curcumin. The conjugate may be used against cancer cells that express the LHRH receptor: pancreas, prostate, breast, testicular, uterine, ovarian, melanoma. LH-Curcumin conjugates may be used against cancer cells that express the LH receptor: prostate, breast, ovary, testis, uterus, pancreas, and melanoma.

The present invention relates to a Chinese medicine for effectively curing hyperplasia of mammary glands. It is made up by using 10 Chinese medicinal materials of white peony root, bupleurum root, lonicera flower, dandelion, white mustard seed and others through a certain preparation process. Its total effective rate can be up to 90.3%.

The invention relates to the field of daily chemical, in particular to a preparation method of a rosa canina fruit extract and application thereof in a skin care cream. The preparation method mainly comprises the steps that 1, dried rosa canina fruits are subjected to superfine grinding so as to pass through a 100-mesh sieve; 2, a composite biological enzyme is prepared; 3, the ground rosa canina fruits are added into a solvent, then the temperature is increased to 50-55 DEG C, then the composite biological enzyme is added, the pH is adjusted by acid to be 4.5-5.0, after the mixture is stirred to be uniform, enzymolysis is kept for 2 H at the temperature of 50-55 DEG C, then the temperature is rapidly increased to 100 DEG C for rapid inactivation, the temperature is decreased to 80 DEG C 1 MIN after inactivation, and reflux extraction is carried out for 1H; 4, the extract is filtered, deslagged, concentrated and dried to obtain an educt. The method has the advantages of being high in catalysis efficiency, mild in catalysis condition, and capable of lowering energy consumption, reducing pollution and simplifying technological procedures. When the rosa canina fruit extract prepared through the preparation method is applied to the skin care cream, the effects of well moistening, moisturizing and repairing skin can be achieved.

The invention provides a processing method for prepared rehmannia roots. The problem that the medicine effect is affected due to the fact that the prepared rehmannia root processing quality is not stable can be effectively solved. The method comprises the following steps of cleaning, wherein by weight, 100 parts of fresh rehmannia roots with the diameter being 3 cm or larger and 10-30 parts of fresh rehmannia roots with the diameter being 1 cm or smaller are cleaned thoroughly with clean water; drying, wherein the cleaned fresh rehmannia roots with the diameter being 3 cm or larger are placed into a microwave vacuum drying device to be dried; slicing, wherein the dried fresh rehmannia roots are cut into slices with the thickness being 4-6 mm; smashing and juicing, wherein the cleaned fresh rehmannia roots with the diameter being 1 cm or smaller is smashed and juiced, the fresh rehmannia root juice is added into the rehmannia root slices and placed into a steamer to be steamed for 1-2 h; the steamed rehmannia root slices are dried, and the rehmannia roots are ripen. The method is simple and easy to implement, losses of the content of the effective component verbascoside are small, the medicine effect is reserved, the clinic requirement for prepared rehmannia root tablets can be effectively met, and the clinical medicine effect is improved.

The invention discloses elsholtzia rugulosa hemsl essential oil soap and a preparing method thereof. The elsholtzia rugulosa hemsl essential oil soap is prepared through, by weight, 800-900 parts of a soap base, 40-60 parts of saponin and 5-10 parts of elsholtzia rugulosa hemsl essential oil. The preparing method comprises raw material preparing, mixing, blending, melting and homogenizing, die feeding and stripping and the like. According to the formula proportion, the soap base, the fresh plant squeeze juice and a saponins nut concentration extracting solution are mixed, heated and stirred to be melted, then the elsholtzia rugulosa hemsl essential oil in the formula proportion is added, uniform stirring is conducted to obtain a primary target object product, and a target object is obtained through soap die forming, cooling and stripping. The effects of unique faint scent, sterilization and inflammation diminishing, acne and mark removing and the like of the elsholtzia rugulosa hemsl essential oil are utilized, the effects of radiation hardening, UV protection, whitening, moisturizing and the like of the fresh natural plant squeeze juice are combined, and the elsholtzia rugulosa hemsl essential oil soap has the effects of the faint scent, sterilization, inflammation diminishing, acne and mark removing, moisturizing and the like, and is smooth and moistening.

The invention relates to the field of mosquito repellent liquids and discloses a spider freeze-dried powder mosquito repellent liquid and a preparation method thereof. The spider freeze-dried powder mosquito repellent liquid utilizes spider freeze-dried powder as a main agent and through compatibility, the spider freeze-dried powder mosquito repellent liquid has substantial mosquito repellent effects. Aiming at symptoms of redness, swelling and itching caused by mosquito bites, the spider freeze-dried powder mosquito repellent liquid has good effects of preventing scar, relieving itching, eliminating swelling and relieving pain. In subtropical zones and tropical rain forest zones, the spider freeze-dried powder mosquito repellent liquid has substantial effects of repelling mosquitoes, eliminating swelling, relieving itching, resisting bacteria and diminishing inflammation.

The invention relates to compounds shown as general formulas (I) and (II), pharmacologically acceptable salt thereof and a preparation method and application thereof. The compounds and the salt can beused for preparing drug for preventing or treating diseases related to a cyclin-dependent kinase (CDK4) inhibitor and drug for treating melanoma, liver cancer, stomach cancer, non-small cell lung cancer, prostatic cancer, thyroid cancer, colorectal cancer, pancreatic cancer, ovarian cancer, breast cancer, esophagus cancer and gastrointestinal cancer.

The present invention discloses a mulberry leaf black tea solid beverage preparation method and processing equipment. The mulberry leaf black tea solid beverage preparation method mainly comprises the following processing steps of freeze drying, mechanical crushing, constant temperature extraction, low temperature concentration, secondary freeze drying, blending and mixing, wet granulation, and drying and packaging. The processing equipment comprises a processing box, a plurality of supports are fixed to the bottom of the processing box, a plurality of feeding barrels are fixed to the upper end of the processing box, a plurality of feeding openings correspondingly communicating with the feeding barrels are formed in the top of the processing box in a penetrating mode, and a plurality of pre-grinding mechanisms are arranged at the inner top of the processing box. The mulberry leaf black tea solid beverage preparation method has the advantages that the prepared mulberry leaf black tea solid beverage is good in taste, good in resolubility, small in size, convenient to carry, instant to drink and capable of being drunk after being brewed with warm water, the condition restriction problem that mulberry leaf black tea can be drunk after being brewed with hot water is solved, and the mulberry leaf black tea solid beverage can serve as an auxiliary hypoglycemic dietary therapy product to be used for daily postprandial blood sugar control of diabetics.

The invention discloses a Chinese herbal medicinal notoginseng beverage and a preparation method thereof. The Chinese herbal medicinal notoginseng beverage is mainly prepared from the following raw materials in parts by weight: 10-15 parts of sweetening agents, 3-8 parts of extracting solutions, 6-11 parts of fructus perillae, 2-7 parts of semen coicis, 2-7 parts of folium cortex eucommiae, 3-8 parts of tremella fuciformis, 5-10 parts of herba moslae, 15-20 parts of mangifera indica pulpa, 1-5 parts of radix adenophora stricta, 2-7 parts of folium notoginseng, 1-5 parts of herba menthae and a proper volume of semen coicis water, wherein the extracting solutions are one or a combination of a ganoderma lucidum extracting solution and a nidus vespae extracting solution. The invention also provides the preparation method of the Chinese herbal medicinal beverage. The preparation method of the Chinese herbal medicinal beverage comprises preparation of Chinese herbal medicines, preparation of semen coicis, decoction, juice squeezing, thinning, sterilization and filling, so that the Chinese herbal medicinal beverage can be obtained. The preparation method of the Chinese herbal medicinal beverage provided by the invention is simple in process, further, does not add any chemical substances, does not generate pollution, and has the functions of nourishing the lung, moistening intestines, clearing away heat, moistening the lung, removing liver-fire, losing weight and the like.

The invention discloses a preparation method and application of an earthworm supernatant protein nano collagen repair compound. The preparation method comprises the following steps: preparing an earthworm supernatant protein; preparing a nano mesoporous transition metal carrier; and preparing the earthworm supernatant protein nano collagen repair compound. The earthworm supernatant protein nano collagen repair compound is applied to collagen repair of animal skin tissues. Compared to the prior art, according to the invention, an active protein ingredient is involved into a transition metal mesoporous nano material and the contact opportunity between the active ingredient and the air is reduced by PLGA, so that when the medicine effect is reserved, the earthworm supernatant protein nano collagen repair compound also has effects of reinforcing biocompatibility and reducing toxicity; and therefore, a medical pharmaceutic preparation with slow release, high efficiency, economy and biocompatibility is prepared so as to fulfill the aim of promoting the collagen repair.

The invention relates to the food field, in particular to new application of orange peel in food processing. The method includes: firstly crushing orange peel, then conducting debittering and drying treatment to obtain orange peel powder, finally mixing an adhesive, oligosaccharide and the orange peel powder evenly, and conducting compression moulding to obtain the weight-reducing biscuit. The weight-reducing biscuit prepared by the method has appropriate sweetness, not only retains the pharmacodynamic effect of orange peel, but also has the efficacy of invigorating stomach, moistening lung and the like, is an advanced green food for obese patients, and is a health food, thus being suitable for popularization and eating. In addition, the preparation method provided by the invention is simple, comprehensively utilizes orange peel, is green and pollution-free, reduces the cost, and improves the added value and competitiveness of the product.

The invention discloses a preparation method and processing equipment of a mulberry-leaf black tea liquid beverage. The preparation method mainly comprises the following processing steps of freeze drying, mechanical smashing, constant-temperature extraction, blending and mixing, vacuum degassing, high-pressure homogenizing and sterilized canning. The processing equipment comprises a mixing tank, wherein a plurality of supports are fixed to the bottom of the mixing tank, a motor is fixed to the bottom of the mixing tank, an output shaft of the motor penetrates through the bottom of the mixing tank and is fixedly provided with a rotating shaft, a water spraying rod and an air spraying rod are fixed to the circumferential side wall of the rotating shaft, a plurality of discharging hoppers are inserted into the top of the mixing tank in a penetrating mode, and the inner wall of each discharging hopper is rotationally connected with a rotating plate through a torsional spring. The preparation method and the processing equipment have the advantages that the manufacturing process is simple, industrial production is facilitated, and compared with directly-brewed mulberry-leaf black tea, the mulberry-leaf black tea liquid beverage is better in taste and widely suitable for being drunk by all classes of people.

The invention discloses a hippocampus preparation, a preparation method thereof and application of the hippocampus preparation. According to the invention, hippocampus freeze-dried powder convenient to clinically apply is prepared by employing related techniques of freeze drying and the like, and compared with a sun-dried product, the hippocampus freeze-dried powder has the characteristics that the drug effect and nutritional ingredients in a hippocampus are well preserved, and the hippocampus freeze-dried powder is convenient to store, blend and take. Through further research, the invention further finds that glycolipid metabolism disorder related diseases can be effectively prevented and improved by oral administration of the hippocampus freeze-dried powder, new indications are added forclinical application of traditional Chinese medicine hippocampus, the clinical application range of the hippocampus is widened, and huge social benefits and economic benefits will be generated in thefields of modernization of traditional chinese medicine, health, medical treatment and the like.