Production process of toothpaste with functions of cleaning teeth, resisting inflammation and sterilizing

A production process and functional technology, applied in the field of daily chemical products, can solve problems such as poor use effect, single efficacy, and poor anti-allergic properties, and achieve less concentration, improved taste, anti-cancer and induction of cancer The effect of cell differentiation

Pending Publication Date: 2021-08-03
HUBEI XIANZHILING FOOD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] There are a variety of toothpaste products on the market, but most of them are not very good at anti-inflam

Method used

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  • Production process of toothpaste with functions of cleaning teeth, resisting inflammation and sterilizing

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Experimental program
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Effect test

Embodiment 1

[0026] Tranexamic acid: Its local chemical name is trans-4-aminomethylcyclohexanecarboxylic acid, a white crystalline powder. It is not a drug itself, let alone a prescription drug. It is a chemical raw material. Of course, this chemical raw material can be made into a prescription drug. It can also be used as an auxiliary material for daily chemical products, such as toothpaste and cosmetics; tranexamic acid is added in dentifrices, and its "hemostatic and anti-inflammatory" effect can be used to prevent periodontal diseases.

Embodiment 2

[0028] Dipotassium Glycyrrhizinate: The study explored the anti-inflammatory activity of dipotassium glycyrrhizinate and its use in toothpaste products. The cytotoxicity of dipotassium glycyrrhizinate was detected by stimulating mouse macrophage RAW264.7 model with lipopolysaccharide (LPS), and the effects of dipotassium glycyrrhizinate on LPS were evaluated by Griess Reagent method and enzyme-linked immunosorbent assay (ELISA) respectively. Stimulate RAW264.7 cells to release inflammatory mediator NO and inflammatory cytokine interleukin-6 (IL-6) to investigate its anti-inflammatory activity. Meanwhile, the in vivo anti-inflammatory effect of toothpaste containing dipotassium glycyrrhizinate was evaluated by using xylene-induced mouse ear swelling model. The experimental results showed that 1000 μg / mL dipotassium glycyrrhizinate could significantly inhibit LPS-stimulated RAW264.7 cells from secreting NO and IL-6, and the toothpaste containing dipotassium glycyrrhizinate also ...

Embodiment 3

[0030] Paeonol: Paeonol has analgesic, anti-inflammatory, antipyretic and anti-allergic effects. It has obvious analgesic effect on pain caused by physical or chemical factors such as tail pressure and acetic acid. It has obvious inhibitory effect on the inflammatory response caused by carrageenan, egg white, formaldehyde, histamine, 5-hydroxytryptamine, bradykinin, xylene and endotoxin. It has obvious antipyretic effect on the rise in body temperature caused by typhoid vaccine and triple vaccine. It has inhibitory effect on type II, III, and IV allergies.

[0031] It has sedative, hypnotic, antibacterial, anti-inflammatory, anti-oxidant, and blood pressure-lowering effects. In terms of daily chemicals, paeonol can inhibit the generation of O2- free radicals in cells, whiten the skin, and restore and fade the pigment deposited in the skin. , Decontamination and plaque; also has anti-inflammatory, swelling and pain relief, anti-allergic, anti-viral and other effects. It has ...

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Abstract

The invention discloses a production process of toothpaste with functions of cleaning teeth, resisting inflammation and sterilizing. The toothpaste is prepared from the following raw materials: sorbitol, water, hydrated silica and polyethylene glycol-8; and the radix puerariae extract is added, and as many as 13 isoflavone substances contained in radix puerariae have a very good regulating effect on a human body, wherein the daidzein, daidzein, puerarin and other active substances have the functions of promoting blood flow of heart and cerebral vessels and retinas, relaxing smooth muscles, relieving spasm, resisting and promoting cancer, inducing cancer cell differentiation, reducing blood sugar, reducing blood pressure, resisting oxidation, clearing heat, dispelling the effects of alcohol, improving memory, enhancing immunity and the like, so that the dipotassium glycyrrhizinate has remarkable anti-inflammatory activity and can be used as a safe and efficient natural sweetening agent to replace sodium saccharin in the toothpaste, the sweetness of the dipotassium glycyrrhizinate is three hundred times that of sucrose, and the dipotassium glycyrrhizinate is healthier to use.

Description

technical field [0001] The invention relates to the technical field of daily chemical products, in particular to a production process of toothpaste with anti-inflammatory and anti-bacterial functions for cleaning teeth. Background technique [0002] Toothpaste is a kind of tooth cleaning product, generally in the form of gel, usually applied on the toothbrush, with the help of the mechanical friction of the toothbrush to clean the surface of the teeth, clean the teeth and their surroundings, purify and refresh the oral cavity, and make the teeth beautiful , Protect gum health and prevent bad breath, teeth cleaning is the most important. Toothpaste has become a necessity in human daily life. [0003] There are various toothpaste products on the market, but most of them are not very good in anti-inflammation and anti-allergic when they are used; moreover, they have a single effect and the effect of use is not good. Contents of the invention [0004] The purpose of the pres...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/25A61K8/34A61K8/35A61K8/39A61K8/42A61K8/46A61K8/63A61K8/73A61K8/24A61Q11/00A61P1/02
CPCA61K8/345A61K8/25A61K8/39A61K8/463A61K8/731A61K8/73A61K8/9789A61K8/42A61K8/63A61K8/35A61K8/24A61Q11/00A61P1/02A61K2800/28A61K2800/592
Inventor 段文杰段光志王学平
Owner HUBEI XIANZHILING FOOD
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