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Device for mouse sarcopenia modeling

A mouse and modeling technology, which is applied to animal drinking devices, animal feeding devices, applications, etc., can solve the problems of no automatic monitoring and inconvenient cleaning of the device, and achieve the effect of convenient cleaning and convenient modeling.

Active Publication Date: 2021-10-22
WEST CHINA HOSPITAL SICHUAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to provide a mouse sarcopenia modeling device for the above disadvantages, to solve the problems of no sarcopenia modeling device, inconvenient cleaning of the device, no automatic monitoring and other monitoring systems

Method used

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  • Device for mouse sarcopenia modeling
  • Device for mouse sarcopenia modeling
  • Device for mouse sarcopenia modeling

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] See attached Figure 1-5 . A device for modeling mouse sarcopenia, comprising a lower box 1, an upper cover 2 and a partition assembly 3; the partition assembly 3 is arranged in the lower box 1 for dividing the inner space of the lower box 1 It is a plurality of mouse activity areas 4; the top of the mouse activity area 4 is provided with a ventilating cover 5; the upper cover 2 is covered on the top of the lower box body 1; the upper cover 2 is provided with an air inlet 6 and an air outlet 7. As can be seen from the above structure, the partition assembly 3 divides the inner space of the lower box body 1 into several mouse activity areas 4, and each mouse activity area 4 puts a mouse, so that the mice will not be mixed together to avoid The modeling mice fight and destroy the modeling environment. The top of the mouse activity area 4 is provided with a breathable cover 5, the breathable cover 5 makes the mouse activity area 4 ventilated, and the breathable cover 5 ...

Embodiment 2

[0029] See attached Figure 1-5 . On the basis of Embodiment 1, the lower box body 1 includes a side shell 8 and a lower cover 9; the lower cover 9 is openably arranged below the side shell 8; an isolation net is provided below the mouse activity area 4 10; the isolation net 10 and the side shell 8 are fixed. It can be seen from the above structure that the side shell 8 is formed by connecting four side walls end to end, the top is connected with the upper cover 2, and the bottom is connected with the lower cover 9; the lower cover 9 and one of the side walls of the side shell 8 are hinged, and are buckled in On the opposite side wall; mice move on the isolation net 10, and the lower cover 9 is supported below the isolation net 10, and the isolation net 10 is covered with padding, and the padding adopts fresh wood shavings or corncobs; When needing to clean up on the bedding material, only need to open lower cover 9, bedding material and ight soil leak from isolation net 10,...

Embodiment 3

[0033] See attached Figure 1-5 . On the basis of embodiment two, it also includes a controller, several drinking devices 15 corresponding to the mouse activity area 4, a feeding device 16 and a behavior monitoring device 17; the drinking device 15 is used to provide corresponding mouse activities The drinking water of the mouse of district 4; Described feeding device 16 is used for providing the food of the mouse of corresponding mouse activity district 4; Described behavior monitoring device 17 is used for monitoring the activity level of the mouse of corresponding mouse activity district 4 .

[0034] The drinking device 15 includes a bottle body 18 and a tube body 19; a plug 20 is fixed on the bottle body 18; the outer side wall of the side shell 8 is provided with a slot 21 corresponding to the plug 20; the plug 20 is inserted into the The slot 21 enables the bottle body 18 to be detachably fixed on the outer side wall of the side shell 8; the tube body 19 is located at ...

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PUM

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Abstract

The invention discloses a device for mouse sarcopenia modeling, and belongs to the field of mouse feeding. The device comprises a lower box body, an upper cover and a partition plate assembly, wherein the partition plate assembly is arranged in the lower box body and used for dividing the inner space of the lower box body into a plurality of mouse activity areas, breathable covers are arranged at the tops of the mouse activity areas, the top of the lower box body is covered with the upper cover, and the upper cover is provided with an air inlet and an air outlet. According to the device for the mouse sarcopenia modeling, the activity space of a mouse can be limited, cleaning is convenient, the water intake, food intake and activity amount of the mouse can be automatically read, interference of other environmental conditions is eliminated, and the mouse sarcopenia modeling is convenient.

Description

technical field [0001] The invention belongs to the field of mouse feeding, and in particular relates to a device for making models of mouse sarcopenia. Background technique [0002] Sarcopenia primarily refers to an age-related loss of muscle mass that is accompanied by a decline in muscle strength and / or physical function. With the intensification of the aging process of society, sarcopenia has become a prominent problem affecting the health of the elderly, and the research on the mechanism and prevention of sarcopenia is a current research hotspot. Selecting and establishing animal models of sarcopenia is the basis for carrying out relevant research, especially in the study of senile sarcopenia. [0003] Due to the complexity of aging and the uncertainty of experimental interventions, there is still no animal modeling method similar to clinical sarcopenia pathology. At present, the common mouse sarcopenia models are hindlimb suspension method, joint position fixation me...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01K1/03A01K1/035A01K7/02A01K5/02A01K29/00
CPCA01K1/031A01K1/035A01K1/0356A01K7/02A01K5/02A01K29/005
Inventor 吴苠铭
Owner WEST CHINA HOSPITAL SICHUAN UNIV
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