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Photocuring skin wound adhesive

An adhesive and light-curing technology, applied in surgical adhesives, applications, medical science, etc., can solve problems such as burning and tingling sensation of skin and wounds, poor market feedback, secondary rupture of wounds, etc., and achieve the elimination of black smoke , Reduce combustion activation energy, improve engine power effect

Inactive Publication Date: 2021-10-22
东莞市瞬力新材料科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] After our investigation, the n-butyl α-cyanoacrylate adhesive currently on the market is cured by moisture, which will release a lot of heat during the curing process, which will cause burning and tingling sensations on the skin and wounds. At the same time, it takes 2-4 hours for complete curing. After curing Poor film-forming property, poor flexibility, easy to cause secondary rupture of the wound, so the current market feedback is not good, and Chinese hospitals still mainly use traditional needle and thread suture surgery

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] A light-cured skin wound adhesive, comprising the following raw materials:

[0036] n-butyl α-cyanoacrylate, fumed silica, polymethyl methacrylate, stabilizer, photoinitiator and accelerator, wherein the following raw materials are included in the weight ratio: n-butyl α-cyanoacrylate: 90 %, fumed silica: 5%, polymethyl methacrylate 3%, stabilizer 1%, photoinitiator 0.8% and accelerator 0.2%.

[0037] In addition, it should be noted that the adhesive of the present invention increases the photoinitiation performance on the basis of moisture curing, and there is a certain conflict between these two curing methods, which leads to the early Polymerization and curing. In order to allow these two curing methods to coexist effectively, we have configured a composite light stabilizer, which contains: citric acid / ketorolac, hydroquinone and acetaminophen, which are actually proven to be used in products The stabilizer also plays a certain anti-inflammatory effect on wounds.

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PUM

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Abstract

The invention aims to provide a photocuring skin wound adhesive. The photocuring skin wound adhesive is prepared from the following raw materials: n-butyl alpha-cyanoacrylate, fumed silica, polymethyl methacrylate, a stabilizer, a photoinitiator and an accelerant. Compared with the prior art, the skin can be tightly attached to the product, wound infection can be effectively prevented, wound healing is accelerated, and the wound can be immediately soaked in water, bathed, subjected to field work and the like after being glued and cured, so that the wound can be effectively protected.

Description

technical field [0001] The invention relates to a photocurable skin wound adhesive. Background technique [0002] α-n-butyl cyanoacrylate adhesive is a mature medical adhesive. It has mature applications in foreign hospitals, and American special forces will carry n-butyl ester medical glue with them to quickly treat wounds in the field. [0003] α-N-butyl cyanoacrylate adhesive medical adhesive is characterized by fast adhesion to body tissues at room temperature, strong adhesion, and non-toxicity. It has little reaction to tissue, does not form thrombus, and can be easily sterilized. It can replace the needle suture operation, so that no trace is left after the skin incision is anastomosed, and it has the function of hemostasis on the wound; it can also be used for the adhesion and hemostasis of internal organs. [0004] After our investigation, the n-butyl α-cyanoacrylate adhesive currently on the market is cured by moisture, which will release a lot of heat during the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L24/02A61L24/00A61L24/06A61L26/00
CPCA61L26/0014A61L26/0004A61L26/0061A61L24/06A61L24/02A61L24/001C08L33/12
Inventor 倪发兴
Owner 东莞市瞬力新材料科技有限公司