Composite material with rapid coagulation effect and preparation method thereof

Abstract

The invention discloses a composite material with rapid coagulation effect and a preparation method thereof, belonging to the technical field of biomedicine. The composite material with rapid coagulation effect is counted in parts by mass, including the following raw materials: 8-20 parts of chitosan, 7-14 parts of salicylaldehyde, 8-16 parts of 2-aminoisonicotinic acid, 1.5-3.5 parts of ferrous sulfate 3-5 parts of dopa and 10-15 parts of disodium hydrogen phosphate. The composite material with rapid blood coagulation prepared by the invention has good product stability, high biological safety, remarkable effect on blood coagulation, simple process and easy industrial production.

Description

technical field

[0001] The invention relates to the field of agricultural technology, in particular to a composite material with rapid coagulation effect and a preparation method thereof. Background technique

[0002] According to statistics, uncontrolled bleeding is the main cause of death, and hemorrhagic shock accounts for 30% to 45% of traumatic injury deaths every year. Therefore, the development of high-efficiency hemostatic materials has become the key to rapid hemostasis and reduction of bleeding mortality. Although hemostatic materials such as glutaraldehyde-crosslinked albumin and fibrin-based bandages have good hemostatic effects, it is difficult for traditional hemostatic agents to control this type of hemostasis in patients with coagulopathy who lack coagulation factors or have dysfunctional hemostasis. Blood loss, which increases the risk of death from massive blood loss. Therefore, controlling hemostasis with coagulopathy bleeding remains a great challenge. ...

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