Unlock instant, AI-driven research and patent intelligence for your innovation.

Device for testing solubility of drugs in digestive organs

A technology for digestive organs and medicaments, applied in the direction of testing pharmaceutical preparations, material inspection products, etc., can solve problems such as irrelevance, and achieve the effect of accurate testing

Active Publication Date: 2021-12-17
HITACHI ZOSEN CORP
View PDF30 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] But, in known device, each vessel is independent of each other, has no connection with each other

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Device for testing solubility of drugs in digestive organs
  • Device for testing solubility of drugs in digestive organs
  • Device for testing solubility of drugs in digestive organs

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0024] figure 1 A device used for a drug dissolution test in a digestive organ according to an embodiment of the present invention is shown. This device includes a plurality of containers 12 , 14 , 16 , and 18 corresponding to the various organs of a human digestive system as a living body. The container 12 forms the stomach chamber, the container 14 forms the duodenal cavity, the container 16 forms the jejunum cavity, and the container 18 forms the ileal cavity. The duodenum, jejunum and ileum can be collectively referred to as the "small intestine".

[0025] It is configured to be able to supply the manually adjusted gastric juice 20 to the container 12 constituting the gastric cavity. Reference numeral 22 is a container for storing gastric juice 20 , and reference numeral 24 is a supply path for supplying gastric juice from the storage container 22 toward the container 12 constituting the gastric cavity. A peristaltic pump 26 is provided in the supply path 24 . These co...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

This is a device for testing solubility of drugs in digestive organs. This device for testing solubility comprises: a plurality of containers 12, 14, 16 and 18 which correspond to the digestive organs of a living body; digestive juice supply devices 20, 24, 40 and 42 which supply digestive juices to containers requiring the supply of digestive juice; liquid supply paths 34, 35 and 70 which are provided between the containers and which extend from the upstream-side containers to the downstream-side containers; feed drive sources 36, 54 and 72 which bring a fluid force to play on a mixed liquid of an orally administered drug and digestive juices in the liquid supply paths; and a control device 90 which controls the supply speed due to the feed drive sources 36, 54 and 72 so as to correspond to the variation over time in the flow rate in the digestive organs of the living body from the upstream side to the downstream side.

Description

technical field [0001] The present invention relates to a device for drug dissolution test in digestive organs, in particular to a device for drug dissolution test in vitro. Background technique [0002] As an apparatus used for a drug dissolution test in a digestive organ, there is known an apparatus provided with a plurality of containers for accommodating artificial digestive fluid corresponding to each digestive organ of a living body. The vessel of this known device for dissolution test is configured such that the dissolution status of the drug can be checked over time in order to check the dissolution status of the drug after oral administration of a tablet or the like or to study the absorption process of the active ingredient. , the pH of the digestive juice dissolved in the drug, etc. [0003] However, in known devices, each container is independent of each other and has no relationship with each other. Therefore, it is different from an actual living body. [00...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/15
CPCG01N33/15
Inventor 横林孝康
Owner HITACHI ZOSEN CORP