Method for analyzing content of ginsenoside in ten-ingredient Xiangdeer capsule

Abstract

The invention relates to a method for analyzing the content of ginsenoside in a ten-ingredient Xiangdeer capsule, and belongs to the technical field of traditional Chinese medicine formulae. The ten-ingredient Xiangdeer capsule gives full play to the value of each traditional Chinese medicine, and has the effects of soothing liver-qi stagnation, softening hardness to dissipate stagnation and the like. The pharmacodynamic material basis of the ginseng is ginsenoside, and the ginsenoside has an adjusting effect on the neuroendocrine function of the pituitary-gonad axis; the ginsenoside can excite pituitary to secrete gonadotropin, promote biosynthesis of DNA and protein synthesis related zymoprotein, increase gonad activity, and balance positive and negative feedback functions of neuroendocrine through a bidirectional regulation effect on pituitary-gonad axis so as to achieve the purpose of reducing estradiol which is abnormally increased. Mammary gland cell proliferation controlled by ovarian hormones is inhibited. According to the method, the internal components of the traditional Chinese medicine are selected as internal standards by adopting a quantitative analysis of multi-components by single marker, and the content of the components to be detected is calculated by measuring the relative correction factor RCF between the traditional Chinese medicine and other components to be detected, so that the use amount of reference substances is reduced, and the cost is saved.

Description

[0001] This case is a divisional application of 201911198034.5 technical field [0002] The invention belongs to the technical field of traditional Chinese medicine formulas, and in particular relates to a traditional Chinese medicine for regulating mammary gland hyperplasia and a method for verifying its efficacy. Background technique [0003] Mammary gland hyperplasia (Hmg) belongs to the category of "breast pain" in traditional Chinese medicine. The basic cause of the occurrence and development of this disease is the dysfunction of the three viscera - liver depression, spleen deficiency, and kidney deficiency. The external manifestations are phlegm coagulation, qi stagnation, and blood stasis. The main ingredients of the existing therapeutic prescriptions are Bupleurum, Fritillaria, Angelica, Mint, Poria, Green Bark, Atractylodes Rhizome, Prunella vulgaris, Radix Paeoniae Alba, Curcuma, Radix Glycyrrhiza, Coptidis Rhizoma, Scutellaria Baicalensis, Pangolin, Turtle Shell, C...

AI Technical Summary

Problems solved by technology

The main ingredients of the existing therapeutic prescriptions are Bupleurum, Fritillaria, Angelica, Mint, Poria, Green Bark, Atractylodes Rhizome, Prunella vulgaris, Radix Paeoniae Alba, Curcuma, Radix Glycyrrhiza, Coptidis Rhizoma, Scutellaria Baicalensis, Pangolin, Turtle Shell, Cortex Moutan, Rhizoma Chuanxiong Salvia miltiorrhiza, Mitsubishi, honeysuckle, even wing, curcuma, coix seed, and dried ginger. The original formula of Taohong Siwu Decoction adopts the method of promoting blood circulation, and on the basis of the main prescription, additional medicines such as Bupleurum, Angelica, Chuanxiong, or the method of dispelling stagnation and relieving pain are self-made prescriptions. Medicines include Radix Bupleurum, Curcuma Curcuma, Radix Paeoniae Alba, Corydalis Corydalis, Prunella vulgaris, Oyster forge and Fritillaria japonicus; There are many types of related Chinese medicine components for oral administration and external application, but the healing effect is not obvious, or the cycle is long; therefore, in the prior art, there is an urgent need for A new technical solution to solve this problem

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