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A glycerol and sodium pentaborate based formulation preventing postoperative adhesions

A technology of sodium pentaborate and glycerol, which is applied in the directions of surgery, surgical drugs, active ingredients of boron compounds, etc.

Pending Publication Date: 2022-01-04
YEDITEPE UNIVSI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In studies in the literature, liquid or soluble gel-like materials with varying contents and active substances absorbed over time were placed at the surgical site, but there was no clear solution to the problem

Method used

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  • A glycerol and sodium pentaborate based formulation preventing postoperative adhesions
  • A glycerol and sodium pentaborate based formulation preventing postoperative adhesions
  • A glycerol and sodium pentaborate based formulation preventing postoperative adhesions

Examples

Experimental program
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Embodiment Construction

[0007] "A formulation based on glycerol and sodium pentaborate for the prevention of post-surgical adhesions" developed for the purposes of the present invention is illustrated in the accompanying drawings, in which:

[0008] figure 1 is a diagram of the glycerol formula.

[0009] figure 2 is a diagram of the sodium pentaborate formula.

[0010] image 3 is a graphical representation of a situation where the liquid of the invention was not applied on the operated rat and there was strong adhesion.

[0011] Figure 4 is a graphic representation of a case where the liquid of the present invention was applied to an operated rat and no adhesions were observed.

[0012] Glycerin and sodium pentaborate based formulations of the present invention are used to prevent adhesions between manipulated tissues and organs at surgical sites due to any type of surgical procedures. This preparation described within the scope of the present invention is a mixture of glycerol, one of the m...

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PUM

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Abstract

The present invention relates to a glycerol and sodium pentaborate based formulation developed for preventing postoperative adhesions occurring between the manipulated tissues and organs. The objective of the present invention is to provide a formulation comprising a mixture of glycerol, which is one of the most abundant biomolecules in the human body, and sodium pentaborate, which is known to have positive effects on wound healing, with the purpose of preventing postoperative adhesions.

Description

technical field [0001] The present invention relates to a formulation based on glycerol and sodium pentaborate, developed to prevent postoperative adhesions that occur between manipulated tissues and organs. Background technique [0002] After any type of surgical procedure on a living organism, when tissue cut at the surgical site is healing, due to early fibrosis and late collagen tissue accumulation, between organs and tissues located at or adjacent to the site Adhesion occurs. The resulting collagenous tissue and the amount of adhesions dependent thereon vary according to many parameters such as the size and duration of the surgical procedure, whether the environment is infected, whether foreign bodies (prosthetic materials) are used, the amount of bleeding and the patient's immune response ability. However, adhesions definitely occur after every surgical procedure. [0003] Postoperative adhesions are a serious problem after any type of surgical procedure. The most ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/047A61K33/22A61P41/00
CPCA61K33/22A61L31/16A61L31/028A61L31/14A61L2400/06A61L2300/102A61L2300/22
Inventor F·萨欣M·E·艾桑O·德米尔
Owner YEDITEPE UNIVSI