Pulse generation circuit with pulse detection function and pulse generation equipment and method

Abstract

The embodiment of the invention provides a pulse generation circuit with a pulse detection function and pulse generation equipment and method. The pulse generation circuit with a pulse detection function comprises a first pulse generation sub-circuit and a first driving circuit, wherein the first driving circuit comprises a first control circuit, a first wire and at least one first gate driving circuit group; the first control circuit is in magnetic induction connection with each first gate driving circuit group through the first wire; each first gate driving circuit group is correspondingly and electrically connected with a first switch module and a second switch module of one first pulse generation unit; and the first control circuit enables the first pulse generation sub-circuit to output a first working pulse signal or a first detection pulse signal to biological tissue. According to the embodiment of the invention, the switch modules can be protected through the first wire, and rapid voltage recovery requirements of an energy storage module of the first pulse generation sub-circuit are met; and meanwhile, the real-time curative effect in an irreversible electroporation tumor ablation process can be monitored in real time, and the ablation effect is improved.

Description

technical field [0001] The present application relates to the field of pulse technology, and in particular, the present application relates to a pulse generating circuit, device and method with a pulse detection function. Background technique [0002] The high-voltage pulsed electric field irreversible electroporation technology uses the pulse generating circuit to output pulse signals to ablate the target cells of biological tissues, which can kill the target cells and achieve the effect of controlling tumors. With the continuous advancement of the clinical application of irreversible electroporation tumor ablation, clinicians find that it is difficult to meet the current treatment needs only by checking the ablation effect by MRI or CT scan 24 hours or even longer after surgery. However, after the existing pulse generation circuit outputs a pulse signal to the biological tissue to ablate the target cells, it cannot evaluate the real-time curative effect during the irrevers...

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Problems solved by technology

[0004] In view of the shortcomings of the existing methods, this application proposes a pulse generation circuit, equipment and method with pulse detection function to solve the problem of poor ablation effect or pulse generation due to the inability to evaluate the real-time curative effect in the process of irreversible electroporation tumor ablation in the prior art The switch module of the circuit is easily damaged technical problems

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