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Biological dressing with scar prevention function and preparation method thereof

A biological dressing and functional technology, applied in the biological dressing with the function of preventing scars and its preparation, in the field of biological dressings, it can solve the problems of aggravated itching, erythema, and height effect, so as to prevent scars, relieve skin itching, and improve appearance Effect

Inactive Publication Date: 2022-03-01
ZHENDE MEDICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

When using scar removal products containing onion extracts alone, many patients’ skin itching has not been improved, and the itching will be aggravated; when scar removal products containing onion extracts are used to improve hypertrophic scars, the appearance of scars, erythema and height have no obvious effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] The dosage form of the biological dressing provided by the present embodiment is a gel, which includes the following components by weight percentage:

[0037] Component A: 52.35% ultrapure water, 8% mussel extract, 8% onion extract, 5% allantoin, 0.75% carbomer 940, 0.05% mass fraction 20% hydrogen Sodium oxide solution and 5% propylene glycol;

[0038] Component B: 89.15% ultrapure water, 0.05% disodium EDTA, 10% mass fraction of 2% carboxymethyl cellulose solution, 0.75% mass fraction of 20% sodium hydroxide solution and 0.05% nitric acid Parkin methyl ester;

[0039] The mass ratio of component A to component B is 1:2.

[0040] The preparation method is:

[0041] 1) Fully swell the carbomer in hot water at 80°C for 30 minutes to form a gel matrix. After cooling to room temperature, add other components in part A under the condition of stirring speed of 500r / min, stir for 15-25 minutes and mix evenly. Stirring can be stopped:

[0042] 2) Dissolve carboxymethyl ce...

Embodiment 2

[0049] The dosage form of the biological dressing provided by the present embodiment is a cream, which includes the following components by weight percentage:

[0050] Component A, aqueous phase:

[0051] 78% ultra-pure water, 10% mussel extract, 10% onion extract and 2% allantoin;

[0052] Component B, oil phase:

[0053] 10% white petrolatum, 8% beeswax, 2% lanolin, 6% glyceryl monostearate, 1.5% Tween-80, 3% vitamin E, 0.05% methylparaben and 69.45% ultrapure water;

[0054] The mass ratio of component A to component B is 1:2.

[0055] The preparation method is:

[0056] 1) Mix the ingredients in Part A according to the listed order, heat to 55-65°C, set the stirring speed to 1000r / min, stir for 3-5min, stop stirring after completely dissolving,

[0057] 2) Mix the ingredients in Part B except vitamin E in the order listed, heat to 70-75°C, set the stirring speed to 1000r / min, and stir for 15-20min. Mix the above components completely and stop stirring. Add the dissol...

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Abstract

The invention discloses a biological dressing with a scar prevention function and a preparation method thereof.The biological dressing comprises a component A and a component B. The component A and the component B have the scar removal and itching relieving functions, the dosage form of the biological dressing comprises gel or cream, the component A comprises a mussel extract and an onion extract, the mussel extract contains an L Dopa group, the onion extract contains an L Dopa group, and the onion extract contains an L Dopa group. L Dopa is combined with an epidermal nerve ending receptor to seal epidermal nerve endings to achieve the itching relieving effect, meanwhile, lysine is contained, mussel mucoprotein becomes a very few basic protein, molecules carry a large number of positive charges in the physiological environment, sick cells are recovered in time, the itching relieving effect is achieved, nerve endings can be passivated through electrostatic interaction, and the effect of relieving itching is achieved. The itching relieving effect is achieved. The biological dressing disclosed by the invention not only can prevent the formation of scars, but also can relieve skin itch, and can improve the appearance, erythema and height of hyperplastic scars of patients when being used for the hyperplastic scars.

Description

technical field [0001] The invention belongs to the field of medical biomaterials, and relates to a biological dressing, in particular to a biological dressing capable of alleviating the itching of patients' scars, improving the appearance of hypertrophic scars, erythema and high degree of scar prevention, and a preparation method thereof. Background technique [0002] A wound is a breach of the integrity and continuity of the human skin. In daily life, there are many types of wounds, including cuts caused by mechanical factors, burns caused by factors such as electricity, heat, and chemicals, and chronic wounds caused by the patient's physiological morbidity. Various wounds on the surface of the human body are unavoidable common symptoms in life. The longer the healing of the wound is delayed, the harder it is for the scars to disappear after healing. Everyone has a desire for beauty, and for most women, they all hope to have smooth skin. Once scars appear, it will bring ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8962A61K35/618A61K9/06A61P17/02A61P17/04
CPCA61K36/8962A61K35/618A61K9/06A61K9/0014A61K47/32A61P17/02A61P17/04A61K2300/00
Inventor 宫宇鲁建国张锐赵鲁苹
Owner ZHENDE MEDICAL CO LTD
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