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Composition comprising lilium lophatherum extract

A composition and technology of bamboo leaves, applied in the direction of drug combination, medical preparations containing active ingredients, drug delivery, etc., can solve problems such as the research on the improvement effect of skin texture, and achieve the enhancement of skin elasticity, improvement of skin texture, and improvement of wrinkles Effect

Pending Publication Date: 2022-03-29
LG HOUSEHOLD & HEALTH CARE LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] However, in conventional cosmetic compositions, only an increase in the synthesis amount of each constituent fiber has been confirmed, and no study has been conducted on the substantial skin texture improvement effect.

Method used

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  • Composition comprising lilium lophatherum extract
  • Composition comprising lilium lophatherum extract
  • Composition comprising lilium lophatherum extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0086] Preparation of Lily Bamboo Leaf Extract

[0087]Prepare whole plant (embodiment 1), root (embodiment 2) and flower (embodiment 3) of Lilium hansonii (Lilium hansonii), add 70% ethanol aqueous solution that is equivalent to 10 times of respective quality, extract 3 at normal temperature days, followed by filtration under reduced pressure. The filtered extract was concentrated with a rotary evaporator (Buchi, Switzerland), and dried to prepare Lilium bamboo leaf extract.

[0088] Preparation of Lilium Plant Extract

[0089] Lilium candidum (Lilium candidum) (comparative example 1), Siberia lily (Lilium Siberia) (comparative example 2) and European lily (Lilium martagon) (comparative example 3) each whole plant adds 70% ethanol equivalent to 10 times of quality The aqueous solution was extracted at room temperature for 3 days, and then filtered under reduced pressure. The filtered extracts were concentrated using a rotary evaporator (Buchi, Switzerland) and dried to p...

experiment example 2

[0112] Confirmation of skin whitening effect

[0113] 1) Tyrosinase inhibition effect

[0114] Tyrosinase was extracted from mushrooms (Mushroom), and commercially available from SIGMA was used. First, dissolve tyrosine as a substrate in distilled water to make a 0.3 mg / ml solution, put 1.0 ml of each solution into a test tube, and then add 1.0 ml of potassium phosphate buffer solution (0.1 mol concentration, pH 6.8) to it and 0.7ml distilled water. 0.2 ml of the sample solution prepared by mixing Examples 1 to 3 of the present invention and Comparative Examples 1 to 3 in an ethanol solution to a final concentration of 100 μg / ml was put into the reaction solution, and then reacted in a constant temperature bath at 37°C 10 minutes. At this time, the control group was prepared by putting only 0.2 ml of ethanol solution instead of the sample solution, and vitamin C was used as the positive control group. 0.1 ml of 2500 units / ml tyrosinase solution was put into each of the re...

preparation example 1

[0138] preparation containing the essence of bamboo leaf lily extract

[0139] In order to confirm the skin-improving effect of the lily of bamboo leaf extract prepared in Examples 1 to 3 above, an essence was prepared according to the composition of Table 6 below.

[0140] [Table 6]

[0141] Ingredients (parts by weight) A B C D Bamboo Lily Extract 2 (Example 1) 2 (Example 2) 2 (Example 3) 0 pure water to 100 to 100 to 100 to 100 ethanol 10 10 10 10 Hexylene glycol 2 2 2 2 glycerin 1 1 1 1 PEG-150 1 1 1 1 Dipropylene glycol 1 1 1 1 Glyceryl ether-26 1 1 1 1 Sodium hyaluronate 4 4 4 4 PEG-8 4 4 4 4 Sodium citrate 1 1 1 1 citric acid 0.5 0.5 0.5 0.5 spices 0.5 0.5 0.5 0.5 sum 100 100 100 100

[0142] Confirmation of Skin Moisturizing Effect-2

[0143] 1) Changes in skin moisture before and after using the essence

[0144] In ...

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Abstract

The lilium lobatum extract according to the present invention exhibits a whitening effect by inhibiting the activity of tyrosinase and reducing the total amount of melanin, improves wrinkles and enhances skin elasticity by promoting collagen synthesis of fibroblasts of the skin and inhibiting the activity of collagenase, and exhibits not only an anti-saccharification effect of inhibiting saccharification but also an anti-saccharification effect of inhibiting saccharification. According to the present invention, the composition exhibits a skin moisturizing effect by promoting the synthesis of hyaluronic acid, exhibits a skin texture improving effect by improving skin roughness, and exhibits irritation relief and a calming effect against pricking, itching, heat and the like, and thus can be usefully used in the preparation of cosmetics, medicines or foods.

Description

technical field [0001] The present invention relates to a composition containing lily of bamboo leaf extract. Background technique [0002] The desire to have fair, supple skin is a universal desire. The color or brightness of the skin is determined genetically by the concentration and distribution of melanin in the human skin, but it is also affected by environmental or physiological conditions such as ultraviolet rays from the sun, fatigue, or stress. Melanin is formed after an enzyme called tyrosinase acts as a catalyst on an amino acid, tyrosine, and is converted into DOPA and dopaquinone in turn, through non- produced by enzymatic oxidation reactions. As such, the production pathway of melanin is known, but the reason why tyrosinase is triggered in the mechanism of inducing melanin synthesis has not yet been elucidated in detail. [0003] On the other hand, there are substances that inhibit tyrosinase activity such as kojic acid and arbutin, hydroquinone, vitamin C (...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9794A61K36/8967A61Q19/02A61Q19/08A61Q19/00A61P17/00A23L33/105
CPCA61K8/9794A61K36/8967A61Q19/02A61Q19/08A61Q19/00A61P17/00A23L33/105A61K2800/522A61K2800/782A23V2002/00A23V2200/318A61P17/04A61K2800/92A61K2236/33A61K2236/35A61K2236/55A61K9/0014A61Q19/007
Inventor 李邵永安永济金吉南陈戊铉
Owner LG HOUSEHOLD & HEALTH CARE LTD
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