Preparation method and application of dressing containing astaxanthin
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A technology of astaxanthin and base materials, which is applied in the field of medical treatment and beauty, and medical materials, can solve the problems of astaxanthin instability, affecting efficacy, and excessive addition, so as to achieve easy skin absorption, comfortable and convenient use, and reduce irritation Effect
Pending Publication Date: 2022-04-05
LIAONING YANYANG MEDICAL INSTR CO LTD
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Problems solved by technology
[0003] However, the solubility and stability of astaxanthin are poor, which limits its application.
The existing problems are as follows: 1) Astaxanthin is insoluble in water and cannot be well applied in many cosmetics; 2) It is not easy to be absorbed by the skin, which affects its efficacy; 3) Astaxanthin is unstable and inconvenient to store and use; 4) Astaxanthin is too dark in color and added in too much amount, which can easily lead to skin staining and affect the appearance
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[0035] A preparation method of a dressing containing astaxanthin comprises the following steps.
[0036] Step 1. Add astaxanthin, moisturizing ingredients, whitening ingredients, natural plant active ingredients, and penetration enhancers into a solvent, and mix evenly to obtain an electrospinning solution 1.
[0037] Step 2. Dissolving the polymer in the electrospinning solution 1 prepared in step 1 to obtain an electrospinning solution 2.
[0038] Step 3. Electrospinning the electrospinning solution 2 prepared in step 2 to the receiving substrate through electrospinning technology, forming a nanofiber layer on the surface of the receiving substrate to obtain a nanofiber film containing astaxanthin .
[0039] Step 4, atomizing the nanofibrous membrane prepared in step 3 to obtain a gel containing nanospheres of active ingredients.
[0040] Further, in step 1, the composition is as follows in parts by weight: 0.01-2 parts of astaxanthin, 0-15 parts of moisturizing ingredient...
Embodiment 1
[0050] A dressing containing astaxanthin. The raw materials are as follows in parts by weight: 0.05 parts of astaxanthin, 2 parts of butanediol, 2 parts of arbutin, 1.8 parts of centella asiatica extract, 0.8 parts of paeoniflorin, azone 1.7 parts, 12.5 parts of PVP, and 100 parts of ethanol, the dressing was prepared according to the above preparation method.
Embodiment 2
[0052] A dressing containing astaxanthin. The raw materials are as follows in parts by weight: 0.05 parts of astaxanthin, 3 parts of vitamin C, 2 parts of butanediol, 2 parts of arbutin, 1.8 parts of centella asiatica extract, paeoniflorin 0.8 parts of azone, 1.7 parts of azone, 12.5 parts of PVP, and 100 parts of ethanol, and prepare dressings according to the above preparation method.
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Abstract
The invention relates to a preparation method and application of a dressing containing astaxanthin. The dressing containing the astaxanthin comprises a mask base material, a nanofiber layer and a protective layer which are sequentially stacked, wherein the nanofiber layer is prepared from the following components in parts by weight: 0.01 to 2 parts of the astaxanthin, 0 to 15 parts of a moisturizing component, 0 to 10 parts of a whitening component, 0 to 10 parts of a natural plant active component, 0 to 5 parts of a penetration enhancer, 2 to 70 parts of a high-molecular polymer and 20 to 100 parts of a solvent. According to the preparation method, water-insoluble substances are wrapped in polymer fibers by utilizing an electrostatic spinning technology to form a dry-state nanofiber membrane, so that the irritation of a solvent to skin is reduced, meanwhile, the polymer protects active ingredients such as astaxanthin wrapped in the polymer, so that the active ingredients can stably exist, and after the polymer is dissolved in water, the active ingredients can be easily dissolved in water. The active ingredients wrapped in the mask can be released in the form of nano microspheres, the active ingredients are small in size and easy to absorb by skin tissues, no preservative is added, and the mask is convenient and safe to use and has remarkable anti-aging, whitening, freckle-removing and wrinkle-removing effects.
Description
technical field [0001] The invention relates to the fields of medical materials, medical treatment and cosmetology, in particular to a preparation method and application of a dressing containing astaxanthin. Background technique [0002] Studies in recent years have confirmed that natural astaxanthin has strong antioxidant activity, which is 550 times that of vitamin E and 10 times that of carotenoids. It is praised as "super vitamin E". Astaxanthin, as a chain-breaking antioxidant, can effectively inhibit lipid peroxidation caused by free radicals. At the same time, it can enhance immunity, remove free radicals in the body and other physiological functions, and has a certain effect on skin cancer caused by ultraviolet rays. It has a very good therapeutic effect and has a very wide range of applications in medical treatment and cosmetology. [0003] However, the solubility and stability of astaxanthin are poor, which greatly limits its application. The existing problems ar...
Claims
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Application Information
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