Household cervical cancer screening reagent card

Abstract

The invention belongs to the technical field of immunology, and particularly relates to a household cervical cancer screening reagent card which comprises a bottom plate, a sample pad, a latex combination pad, a nitrocellulose membrane and an absorption pad, detection lines and a quality control line are arranged on the nitrocellulose membrane, the detection lines comprise a p16 detection line and a ki-67 detection line, and the quality control line comprises a quality control line and a quality control line. The p16 detection line, the ki-67 detection line and the quality control line are parallel to one another, and the p16 detection line and the ki-67 detection line are respectively obtained by spraying a solution of a p16-point membrane antibody and a solution of a ki-67-point membrane antibody on the nitrocellulose membrane. According to the household cervical cancer screening reagent card, the p16 point membrane antibody and the ki-67 point membrane antibody are adopted to obtain the p16 detection line and the ki-67 detection line respectively, detection results of the two detection lines are combined and analyzed, various physical conditions can be evaluated, the detection accuracy is improved, in addition, the reagent card is simple in using method, and the results are simple and easy to understand.

Description

technical field [0001] The application belongs to the technical field of immunology, and in particular relates to a household type cervical cancer screening reagent card. Background technique [0002] Cervical cancer is one of the most common gynecological malignancies. According to statistics, the high incidence age of carcinoma in situ is about 30-35 years old, and the high incidence age of invasive cancer is about 45-55 years old. In recent years, the incidence of cervical cancer has a younger trend. . Regular cervical cancer screening helps to detect and treat cervical cancer and precancerous lesions at an early stage, reducing the incidence and mortality of cervical cancer. [0003] Cell carcinogenesis is characterized by unlimited proliferation of cells, that is, out of control of cell cycle regulation. Normal P16 protein has an inhibitory effect on cancer. However, the abnormal expression of P16 (such as mutation, deletion, and methylation inactivation) will make i...

AI Technical Summary

Problems solved by technology

All in all, the above technologies have disadvantages such as high professional requirements, complicated process, long time consumption, high requirements on the use site, and high price, and are not suitable for household use.

Images