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1593results about How to "Simple result" patented technology

Primer pair, probe and kit used for noninvasive polygene methylation combination detection for early stage colorectal cancer and applications thereof

The invention relates to a primer pair and a probe used for noninvasive polygene methylation combination detection for early stage colorectal cancer, and includes the primer pair and the probe used for detecting methylation of genes Spetin9, NDRG4, BMP3, THBD and SDC2 and the primer pair and the probe for internal reference ACTB; the sequences of the primer pair and the probe are represented as the SEQ ID No.1 to the SEQ ID No.18. The invention also provides a kit containing the primer pair and the probe and applications thereof. The application method includes free DNA extraction from a plasma specimen, sulfite conversion, PCR amplification reaction, fluorescent signal detection and result determination. The kit and the method are suitable for methylation detection of the five genes Spetin9, THBD, SDC2, NDRG4 and BMP3 in human peripheral blood; compared with a conventional colorectal cancer diagnosis method, the application method fully utilizes the free DNA extraction from a plasma specimen, the DNA methylation and QPCR associated technologies, thus developing the kit having high sensitivity and specificity. The primer pair, probe and kit are used for performing early stage noninvasive screening to human colorectal cancer.
Owner:上海酷乐生物科技有限公司

Double safety and effectiveness inspection method of human lumbar bone and implant

The invention provides a double safety and effectiveness inspection method of human lumbar bone and implant, and belongs to the field of medicine. The method comprises the following steps: acquiring a 3D (three-dimensional) rendering model of lumbar body bone, lumbar disc and interspinous ligament by a 3D reconstruction technology; performing 3D grid division to the 3D rendering model, and giving attributes of a heterogeneous material to the 3D rendering model; performing 3D modeling to an implant; assembling the lumbar body bone, the lumbar disc, the interspinous ligament and the implant, and analyzing stress and strain of the assembly by adopting uniformly distributed nodal load through a finite element analysis method; simulating visible finite element analysis by a computer before the implant is implanted into a human body. Therefore, the verification requirement to bone and implant double safety and effectiveness can be fulfilled, the damage of the implant to original human lumbar bones can be prevented, double safety and effectiveness of the bones and implant can be guaranteed, the manufacture cost can be effectively reduced along with convenience and quickness, and individual and industrial manufacturing of a human lumbar bone implant can be realized. The method is applicable in the field of implant stress-strain analysis in the orthopedics department.
Owner:UNIV OF SHANGHAI FOR SCI & TECH

Polymerization process using separated flow

Disclosed is a polymerization process comprising feeding a monomer as a raw material, a polymerization catalyst, and optionally, an inert medium to a tubular reactor in a pressurized state; permitting a part of the raw material monomer and the inert medium fed to the reactor to form a gas phase and the remainder to form a liquid phase, so that both of the gas phase comprising the raw material monomer and / or the inert medium and the liquid phase comprising the raw material monomer and / or the inert medium are present in the reactor, wherein said liquid phase may contain a resulting polymer as a solid, and so that a gas-liquid separated flow or a gas-liquid-solid separated flow has the gas phase that is continuous in the direction of flow is formed in the reactor; and polymerizing the raw material monomer while carrying the liquid phase by the gas phase flow, wherein the ratio of a volume flow rate of the liquid phase to a volume flow rate of the gas phase at the outlet of the reactor is 0.00001 to 100,000. According to the polymerization process, polymerization can be accomplished with excellent thermal efficiency and small power energy, and besides various polymers almost free from restrictions on their properties such as viscosities and melting points can be produced.
Owner:MITSUI CHEM INC

Intelligent pairing method applied to online stowage of vehicles and goods

InactiveCN104866997AKnow the comprehensive loading situationFind quicklyLogisticsSpecial data processing applicationsSpatial methodsSpatial clustering
The invention discloses an intelligent pairing method applied to online stowage of vehicles and goods. Information of supply of goods and platform vehicles issued by a goods owner is fully considered based on a word segmentation spatial clustering method, and the information of supply of goods issued by the goods owner is subjected to word segmentation from multiple dimensions, a vehicle information clustering space is constructed, and online intelligent pairing of the supply of goods and vehicles is achieved by the floating space and fuzzy filtering; a plurality of attributes influencing vehicle selection are divided into sequential layers associated with one another based on a multi-attribute decision making model, thus being methodized, and the matched vehicles are optimally sorted according to vehicle transaction evaluation and mass data of the platform, so that the result can be more intuitively presented. According to the intelligent pairing method applied to online stowage of vehicles and goods, the intelligent optimization pairing problem of vehicles and goods in the electronic commerce platform taking logistics service as a transaction object is well processed by the accurate big data mining analysis and the complicated model algorithm, so that the platform members or other members can quickly and accurately find the best fit stowage vehicle from the numerous vehicles and make a selection according with own requirements.
Owner:NANJING UNIV

Teaching equipment for quantum computation and quantum precision measurement

The invention relates to teaching equipment for quantum computation and quantum precision measurement. The teaching equipment for quantum computation and quantum precision measurement comprises a laser pulse generation module, an optical path module, a quantum sensor and a signal acquisition module. The laser pulse generation module is used for emitting laser pulse. The optical path module is arranged along an optical path of the laser pulse. The optical path module comprises a mirror bracket connected by means of a guide bar. A first collimation focusing element, the quantum sensor, a secondcollimation focusing element, a filtering element and a photodetector are sequentially arranged on the mirror bracket along the optical path. The quantum sensor is excited to generate fluorescent light by means of the laser pulse under the action of a magnetic field. The signal acquisition module is connected with the photodetector, and is used for collecting an electrical signal corresponding tothe fluorescent light. After the teaching equipment provided by the invention is adopted, students can complete a demonstration experiment of quantum algorithm and quantum precision magnetic measurement by means of manual operation, thereby mastering the basic principle of the quantum computation. The students can process the original experimental data so as to deepen the understanding of the quantum computation and the quantum precision measurement.
Owner:CHINAINSTRU & QUANTUMTECH (HEFEI) CO LTD

System and method for measuring unfrozen water content in frozen soil by pulse nuclear magnetic resonance (NMR)

The invention relates to a system and a method for measuring unfrozen water content in frozen soil by pulse NMR, aiming at the problems that, in the measurement of unfrozen water content, measuring procedures are complex, operators need relatively high electromagnetism theoretical basis, and operations are difficult; a plurality of test pieces are needed under multi-temperature and multi-pressure working conditions, and the test pieces are exposed in normal temperature to influence measurement precision. The system is characterized in that a soil testing tube is disposed in a ceramic tube; a temperature signal input end of a temperature sensor is disposed in the soil testing tube; a temperature signal output end of the temperature sensor is connected to the temperature signal input end of a temperature control valve. The method is characterized in that different relaxation time of solid water, combined water and free water in attenuation process are stipulated when free attenuation signals of magnetization intensity are fitted, so that the magnetic field intensity value corresponding to the free attenuation signals of magnetization intensity during the relaxation time can be obtained. The system and method of the present invention measure the unfrozen water content in frozen soil.
Owner:HARBIN INST OF TECH

Construction method of ultra-deep underground diaphragm wall in water-rich soft-soil area

The invention relates to the technical field of civil engineering construction, in particular to a construction method of an ultra-deep underground diaphragm wall in a water-rich soft-soil area. The construction method comprises the following steps: making an analysis and research on the stability of trench walls of the underground diaphragm wall and doing relevant preparations, preparing wall protecting slurry, building a guide wall, performing trenching construction, wall cleaning and sediment removal, manufacturing and hoisting reinforcing cages, backfilling joints between trench sections, and pouring wall concrete. According to the construction method, through a stability analysis method that introduces strength reduction, the security coefficients of stability of the trench walls are calculated based on a finite difference method; through parameter-reduction circular calculations, not only the limit stress and large deformation state of the trench walls but also the stability coefficients of the trench walls are obtained, which has practice guiding significance in construction; and the results are simple and practical and conform to the habits in the engineering field, and the stability requirements of the trench walls are effectively guaranteed, so that the engineering construction can be completed safely and fast with high quality.
Owner:CHINA RAILWAY NO 2 ENG GRP CO LTD +1

Detection equipment for welding spot failure of whole set of white vehicle body

The invention relates to detection equipment for welding spot failure of a whole set of white vehicle body. The detection equipment comprises a white vehicle body welding assembly, a vibration exciter and an acceleration sensor, wherein the white vehicle body welding assembly is fixedly arranged on a rack through a special clamp system; one side of the vibration exciter is connected with a data control and acquisition system; the other side of the vibration exciter is a free end for vibration excitation; the acceleration sensor is attached to a key part of the white vehicle body to be detected by using a magnet; the data control and acquisition system is connected with the acceleration sensor and is used for simply processing the acquired voltage signal and then transmitting data to a microcomputer; the data control and acquisition system and the microcomputer form a data detection and analysis system, i.e. an MIMO (Multiple Input Multiple Output) system; and the MIMO system integrates a signal acquisition system and can be used for modal analysis and damage identification of residual force vector as well as can be used for sampling, analyzing and processing the signal acquired in a current area to obtain an accurate detection result.
Owner:HUNAN UNIV AISHENG AUTO TECH DEV

Method for detecting nucleic acid by colloidal gold chromatography technology and reagent kit

The invention discloses a method for detecting nucleic acid by a colloidal gold chromatography technology and a reagent kit, and belongs to the technical field of medical biology. A universal test paper strip for nucleic acid detection is provided; colloidal gold particles are marked on a universal probe 1, and then, the universal probe is fixed on a glass cellulose membrane; the probe sequence is designed into a universal sequence; the test paper strip is fixed on a PVC (polyvinyl chloride) bottom plate; a sample pad, glass fiber, an NC membrane and water absorption paper are in sequential arrangement from the left side to the right side, wherein a T line (detection line) and a C line (quality control line) are arranged on the NC membrane; antibodies to labels b cover the detection line; antibodies to labels a cover the quality control line; the specificity probe A series and the specificity B series successfully combine a gold mark probe and nucleic acid amplification fragments in series; the specificity detection of nucleic acid amplification fragments is realized. The method has the advantages that the technical requirement on the experiment personnel is low; the required detection time is short; special instrument equipment is not needed; the popularization to basic levels and remote rural area medical institutions is easy.
Owner:武汉中帜生物科技股份有限公司

Method for computing electromagnetic force of transformer iron core based on finite element method

The invention discloses a method for computing electromagnetic force of a transformer iron core based on a finite element method. The method comprises the steps that structural parameters of a winding, the iron core and a fuel tank of a transformer are collected, and then a three-dimensional geometric grid model of the transformer is established; the three-dimensional geometric grid model is input into software, sinusoidal currents with a phase different of 120 DEG are applied to the cross section of the three-phase low voltage winding respectively, and Dirichlet boundary conditions are applied to the outer side of the structural grid model; and an instant electromagnetic field is solved by a virtual displacement method, magnetic field energy is computed, a virtual work method is used to compute instant electromagnetic force borne by the transformer iron core and the winding, FFT is conducted to the instant electromagnetic force, and frequency domain distribution of the electromagnetic force of the iron core can be obtained. The computation method disclosed by the invention is direct and convenient; electromagnetic vibration and force bearing situations of the transformer iron core can be analyzed from the perspective of energy; each influential factor on force bearing of the iron core is considered comprehensively; and computation results are accurate and reliable.
Owner:CHINA ELECTRIC POWER RES INST +1
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