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47results about How to "Realize separation detection" patented technology

Optical fiber Bragg grating pressure sensor and corresponding measurement method thereof

The invention discloses an optical fiber Bragg grating pressure sensor and a corresponding measurement method thereof, and the sensor comprises a housing, an elastic diaphragm, an L-shaped uniform strength beam and an optical fiber Bragg grating, wherein an opening is arranged at the top end of the housing, the opening and internal space of the housing constitute a cavity body, the elastic diaphragm covers the opening, the uniform strength beam is arranged in the cavity body, a pressure block is arranged at the free end of a beam arm of the uniform strength beam, a hard boss which is tightly connected with the pressure block is arranged on the lower surface of the elastic diaphragm, the optical fiber Bragg grating is mainly constituted by connecting two Bragg gratings with the identical temperature gradient in series through an optical fiber, and the two Bragg gratings are respectively connected on the upper surface and the lower surface of the beam arm. The sensor has the advantages that the elastic diaphragm is in rigid connection with the beam arm during the design, thereby not only improving the measurement precision, but also reducing the process difficulty; as the optical fiber Bragg grating is mainly constituted by the two Bragg gratings with the identical temperature gradient, the sensor can solve the temperature cross sensitivity problem during the measurement.
Owner:NINGBO SHANGONG CENT OF STRUCTURAL MONITORING &CONTROL ENG

Harmonic and inter-harmonic separation detecting method and device suitable for vessel electric power system

The invention discloses a harmonic and inter-harmonic separation detecting method and device suitable for a vessel electric power system, and belongs to the technical field of vessel electrical engineering. The device comprises a voltage transducer, a current sensor, a chassis wiring terminal, a signal conditioning circuit, a data acquisition card and an industrial control computer, wherein the wiring terminal, the data acquisition card and the signal conditioning circuit are mounted inside the industrial control computer; the industrial control computer acquires input data through a standard serial port, and LabVIEW software of a virtual instrument is used for restoring collected signals according to the transformation ratio, and original signals are recorded; the comprehensive detection on parameters such as frequency, amplitude value and phase of fundamental wave, harmonic and inter-harmonic can be completed; the detection result can be directly displayed on the liquid crystal display of the industrial control computer. According to the invention, a frequency tracking algorithm, a fundamental wave and harmonic extraction algorithm and an inter-harmonic detection algorithm are adopted to implement the fundamental wave, harmonic and inter-harmonic separation detection.
Owner:NO 719 RES INST CHINA SHIPBUILDING IND

Zero dead volume capillary electrophoresis and laser induced fluorescence detection online derivatization device

The invention relates to a zero dead volume capillary electrophoresis and laser induced fluorescence detection online derivatization device, in particular, a zero dead volume hollow fiber film reactor is connected behind a capillary electrophoresis separation column, a fluorescence derivatization agent enters a system through a film and directly carries out online derivatization on samples such as protein, polypeptide and the like, and a product is detected through a laser induced fluorescence detector behind the reactor. The zero dead volume capillary electrophoresis and laser induced fluorescence detection online derivatization device has the characteristics that online fluorescence derivatization is carried out on samples such as micro (even trace) proteins, polypeptide and the like by using the hollow fiber film reactor, and the defects of large sample loss, complexity in operation, long time consumption and the like in an offline derivatization process are overcome. Compared with other online reactors, the zero dead volume capillary electrophoresis and laser induced fluorescence detection online derivatization device has the advantages of small dead volume, less consumption of reagents, controllable derivatization temperature and time, low cost, multiple functions, convenience and stability for operation, and wide application prospect.
Owner:EAST CHINA UNIV OF SCI & TECH

Non-contact conductivity detector and detection method

The invention relates to a detection technique for conductance which is a detecting apparatus and method for separation detecting of capillary electrophoresis, electricity chromatogram and microcylinder liquid phase chromatogram. This invention comprises function signal generator, detecting electrode, electrode fixing device, signal processing circuit, wherein the two detecting electrodes are in telescopic tubular shape and are directly covered on both ends of capillary; and electrode fixing device is composed of two boards with notches in and two detecting electrodes are located in the notches and are connected separately with signal processing circuit; the above components are set in one metal shielding box; the guiding means of capillary is fixed on the side wall of the box; and the guiding wire of detecting electrode is led by the guiding hole and thus is connected with output edge of function signal generator. This invention is of simple structure and high accuracy and good utilization.
Owner:DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI

Application of graphene quantum dot in hydrophilic chromatographic analysis

The invention relates to an application of graphene quantum dot in a hydrophilic chromatographic analysis. The method comprises the following steps: 1) bonding the graphene quantum dot on silica gel;2) filling a chromatographic column with the graphene quantum dot-modified silica gel; and 3) performing separating analysis on an analyte. The graphene quantum dot can be taken as a hydrophilic chromatogram fixed-phase component, hydrophilic performance of the fixed-phase is enhanced, and the fixed phase contains a plurality of strong-polar functional groups, so that a plurality of strong-polar substances can be kept and separated. The graphene quantum dot can be used as the effective components of the hydrophilic chromatogram fixed-phase, the preparation is simple, and stability is high.
Owner:LANZHOU INST OF CHEM PHYSICS CHINESE ACAD OF SCI

Method for simultaneously determining 19 sun-screening agents in cosmetics

The invention relates to the technical field of analysis and detection, in particular to a method for simultaneously determining 19 sun-screening agents in cosmetics. The method comprises the steps ofpreparation of a mono-standard mother solution, preparation of mixed standard solutions, preparation of a series of mixed standard solutions, preparation of test product solutions and liquid chromatography determination. Response values of a series of mixed standard solutions and the test product solutions are in a linear range of instrument detection, are qualitative according to peak retentiontime and are quantitative according to peak area. The sample processing method is simple and effective. Simultaneous separation and detection of 19 sun-screening agents on a C18 chromatographic columnare achieved. The method is simple, convenient, environmentally friendly, high in accuracy and good in repeatability and durability.
Owner:青海省药品检验检测院

Microplastic detection device and method based on pyrolysis-mass spectrometry technology

The invention relates to a microplastic detection device and method based on a pyrolysis-mass spectrometry technology, aiming to solve the technical problem that a microplastic content research devicein the prior art is complex in structure and inconvenient to operate, cannot accurately perform quantitative analysis on components in microplastics, is easily disturbed by the environment, has largeerrors and low accuracy, wastes time and labor, has a large instrument occupancy area, can only be operated in labs, and is difficult to be applied to on-site detection. According to the microplasticdetection device based on the pyrolysis-mass spectrometry technology provided by the invention, the whole device is a closed gas path device system connected by pipelines, and the devices are sequentially connected, including a working gas source, a pyrolysis device, a filter and a mass spectrometer; after a microplastic sample is put into the pyrolysis device, the pyrolysis device performs pyrolysis on the microplastic sample, and pyrolysis products of the microplastic sample are driven by working carrier gas and filtered by the filter to enter the mass spectrometer for detection and analysis; and the invention also provides a microplastic detection method thereof. The scheme of the invention is widely applied to the technical field of microplastic detection.
Owner:HARBIN INST OF TECH AT WEIHAI

Fiber glass raster stress temp sensor

The disclosed sensor includes fiber of sensing probe, an insulative fixed frame and two insulative moving frames. An F shaped moving frame and an L shaped moving frame arranged in interlacing are installed on the fixed frame. Optical fiber of sensing probe passing through the interlaced part of the two moving frames is installed on the fixed frame. Three segments of fiber gratings positioned in interlaced and separated part of the two moving frames are made on fiber of sensing probe. First segment of fiber is in use for measuring stress. Two other segments of fiber gratings having same peak wavelength in reflectance spectrum are in use for measuring stress and temperature. Using principle of differential amplification, the invention raises measuring sensitivity, solves crossed sensitivity so as to be able to apply in high voltage and high electromagnetism harsh environment.
Owner:SHANGHAI JIAO TONG UNIV

Mixed fillers of liquid-phase chromatographic column and chromatographic column

The invention relates to mixed fillers of a liquid-phase chromatographic column and the chromatographic column, and relates to the technical field of analytical chemistry. The mixed fillers of the liquid-phase chromatographic column comprise long-chain alkyl dimethyl silane bonded silica gel and acylamino silane bonded silica gel in a weight ratio of 10:1-1:10, wherein the difference of the mean particle diameter is in a range of between -20 and 20 percent and the difference of the specific weight is in a range of between -20 and 20 percent. In the chromatographic column made by the mixed fillers, the mixed fillers are filled in a column pipe; the outer sides of the two ends of the column pipe are connected with a pipeline through internal thread; the inner sides of the two ends of the column pipe are provided with sieve plates used for preventing the mixed fillers from leaking outwards; one end of the column pipe is provided with a liquid inlet; and a mobile phase enters the chromatographic column from the liquid inlet. The characteristics of the mixed fillers of the liquid-phase chromatographic column are applied to chromatographic separation under the condition of the mixed mobile phase containing acetonitrile and aqueous solution, wherein the separation application is the chromatographic separation and detection of a sample containing a compound with extremely strong hydrophilism and a compound with extremely strong lipotropism simultaneously; and the separation detection of all the components can be performed once under the condition of equal-grade liquid-phase chromatogram.
Owner:天津博纳艾杰尔科技有限公司

Pretreatment method and quantitative detection method for endogenous sugar phosphate compound in plant sample

The invention discloses an analysis method for a variety of sugar phosphate compounds including endogenous trehalose-6-phosphate in a plant sample. The method comprises the following steps of: extracting the endogenous sugar phosphates through a solvent; adsorbing and removing the hydrophobic impurities in the extracted solution through a reversed-phase SPE column; using the diazo groups in a derivatization reagent to carry out derivatization reaction on the phosphate groups common to the sugar phosphate compounds; and in combination with the liquid chromatography and mass spectrometry, realizing the separation detection of the endogenous sugar phosphate isomers in the plant sample. The analysis method is simple, accurate and high in throughput, can achieve the baseline separation of the sugar phosphate isomers on a hydrophilic chromatographic column and guarantee the higher detection sensitivity, and finally can realize the separation detection of the endogenous sugar phosphates in amicroplant tissue sample.
Owner:WUHAN UNIV

Mixed fillers of liquid-phase chromatographic column and chromatographic column

The invention relates to mixed fillers of a liquid-phase chromatographic column and the chromatographic column, and relates to the technical field of analytical chemistry. The mixed fillers of the liquid-phase chromatographic column comprise long-chain alkyl dimethyl silane bonded silica gel and acylamino silane bonded silica gel in a weight ratio of 10:1-1:10, wherein the difference of the mean particle diameter is in a range of between -20 and 20 percent and the difference of the specific weight is in a range of between -20 and 20 percent. In the chromatographic column made by the mixed fillers, the mixed fillers are filled in a column pipe; the outer sides of the two ends of the column pipe are connected with a pipeline through internal thread; the inner sides of the two ends of the column pipe are provided with sieve plates used for preventing the mixed fillers from leaking outwards; one end of the column pipe is provided with a liquid inlet; and a mobile phase enters the chromatographic column from the liquid inlet. The characteristics of the mixed fillers of the liquid-phase chromatographic column are applied to chromatographic separation under the condition of the mixed mobile phase containing acetonitrile and aqueous solution, wherein the separation application is the chromatographic separation and detection of a sample containing a compound with extremely strong hydrophilism and a compound with extremely strong lipotropism simultaneously; and the separation detection of all the components can be performed once under the condition of equal-grade liquid-phase chromatogram.
Owner:天津博纳艾杰尔科技有限公司

Mobile phase for separating phospholipids in high efficiency liquid chromatography

The invention relates to a mobile phase for separating phosphatide by a highly effective liquid phase chromatography. The components of the mobile phase comprise 10 percent to 50 percent of methyl alcohol, 50 percent to 85 percent of acetonitrile, 0.5 percent to 3 percent of fluorinated organic acid, and 0.5 percent to 3 percent of water. Through the long-term operation, the mobile phase of the invention cannot result in any deposit, cannot damage a pump system, and has no damage to the pump system of a liquid phase chromatographic instrument; the mobile phase can be used to detect the separated phosphatide in an evaporative light-scattering detector, compared with an ultraviolet detector, the base line detected by the evaporative light-scattering detector is stable, the quantitative analysis is easy, the sensitivity is high, and the application of the mobile phase has no limit; compared with the gradient method, the method of the invention uses a single pump to realize the separating detection; when the mobile phase adopts the appropriate compounding ratio, besides the phosphatide can be separated, the unknown materials that cannot be separated by the other mobile phases can also be separated. When the mobile phase of the invention applies to the isocratic eluting, the operation is simple and time-saving, the reproducibility is good, and the duplicity is easy.
Owner:西安血氧生物技术有限公司

Positive-phase liquid chromatogram-tandem mass spectrum detection method for nicotine optical isomers in tobacco and tobacco products

The invention relates to a positive-phase liquid chromatogram-tandem mass spectrum detection method for nicotine optical isomers in tobacco and tobacco products. The positive-phase liquid chromatogram-tandem mass spectrum detection method is characterized in that nicotine in tobacco leaves is extracted by a NaOH (sodium hydroxide) solution and n-hexane, the nicotine optical isomers are separated by a chiral chromatographic column, a post-column high pressure liquid output pump is used for introducing isopropyl alcohol and separating flow, and the tandem mass spectrum is used for analyzing, so as to complete the separation and sensitive detection of S-(-)-nicotine and R-(+)-nicotine in the tobacco and tobacco products. The positive-phase liquid chromatogram-tandem mass spectrum detection method has the characteristics and beneficial effects that the post-column high pressure liquid output pump is used for introducing isopropyl alcohol and separating flow, so that the amount of non-polarity solvent entering mass spectrum is reduced, the amount of isopropyl alcohol of polarity solvent is compensated, the ionizing efficiency is improved, the requirement of liquid chromatogram-tandem mass spectrum analysis is met, and the analysis sensitivity is improved; compared with the prior art, the chromatographic resolution of the two types of nicotine optical isomers is high, and the difference of retention times is 1min; the analysis time is short, and is only 17min.
Owner:ZHENGZHOU TOBACCO RES INST OF CNTC

Method for measuring furosemide by high performance liquid chromatography and genetic toxic impurity in its preparation

The invention discloses a method for measuring genetic toxic impurity C in furosemide by high performance liquid chromatography. The method comprises using a carbon-18 chromatographic column and usinga mixed solution of phosphoric acid water and acetonitrile as a mobile phase, wherein the volume ratio of the phosphoric acid water to the acetonitrile in the mobile phase is (97 to 85): (3 to 15); and using a mixed solution of acetonitrile and water as a diluent. The invention provides a method for separating and measuring the genetic toxic impurity C in furosemide, which finally simplifies thecontrol method of the genetic toxic impurities, improves the quality control requirement of the furosemide, and ensures the effectiveness and safety of the furosemide.
Owner:南京科宁检测科技有限公司

Method for separating and detecting imipramine and trimipramine

The embodiment of the invention discloses a method for separating and detecting imipramine and trimipramine. The method comprises the following steps: using a capillary tube as separation channel and a mixed solution of trihydroxymethylaminomethane, beta-cyclodextrin and acetonitrile as separation solution to separate imipramine and trimipramine, and on the end of the capillary tube, using a tris(2,2'-bipyridyl)ruthenium (II) electrochemical luminescence system to detect imipramine and trimipramine to finally realize the separation and detection of imipramine and trimipramine. The method which uses a capillary electrophoresis-electrochemical luminescence combination device to separate and detect imipramine and trimipramine has the advantages of simple experimental devices, easy and practical operation method, low cost, high separation efficiency, high detection sensitivity and the like. When the method provided by the invention is used to separate and detect imipramine and trimipramine, the limit of detection of imipramine and the limit of detection of trimipramine are separately 5.0*10<-9>mol / L and 1.0*10<-9>mol / L.
Owner:CHANGZHOU INST OF ENERGY STORAGE MATERIALS &DEVICES

Online hydrogen purity detection instrument as well as use method and application thereof

The invention relates to the field of gas detection and the field of optical sensing, and particularly provides an online hydrogen purity detection instrument as well as a use method and application thereof. The hydrogen purity online detection instrument comprises: a gas separation module and a light source (3), wherein each component gas in gas to be detected is separated in the gas separation module, the light source has the functions of current regulation and temperature regulation, and the line width of an emitted beam is far smaller than the single absorption line width of the gas to be detected and the spectral line width of a traditional infrared light source, and the separated gas is irradiated by the light source (3) to obtain a light signal; and a signal processing unit which is used for processing the optical signals to obtain spectral data of each gas in each time period, and is matched with analysis software to obtain composition data of the gas to be detected. The problems that in hydrogen purity detection in the prior art, impurity content analysis is insufficient, only single-point detection can be achieved in a detection area, the gas cross interference phenomenon is serious, gas detection consumes long time, and online detection cannot be achieved are solved.
Owner:SHANDONG UNIV

Preparation method of strong cation exchange chromatographic filler for glycosylated hemoglobin

The invention provides a preparation method of a strong cation exchange chromatographic filler for glycosylated hemoglobin. The preparation method comprises the steps of step 1, carrying out primary polymerization on a first monomer to form microspheres with a monodisperse particle size; step 2, further cross-linking and polymerizing the first monomer to enlarge the particle size of the microspheres; step 3, further introducing a second monomer for polymerization, and polymerizing functional groups on the microspheres; and step 4, cleaning, and removing the solvent, the dispersing agent, redundant monomers and the like in the reaction system. According to the invention, the defects in the prior art are overcome, the design is reasonable, the structure is compact, and the monodisperse strong cation exchange chromatographic filler with the particle size of 2-15 microns is obtained through a multi-step dispersion polymerization method. The complex operations such as staged treatment or seed swelling and microsphere post-modification in the synthesis process of the existing filler synthesis method can be avoided, and the preparation method is simpler and more controllable. The strong cation exchange chromatographic filler obtained by adopting a multi-step dispersion polymerization method can realize separation and detection of glycosylated hemoglobin.
Owner:WUXI CITY KAIAOSHAN BIOPHARML TECH

Mobile phase for separating levodopa in broad beans in high efficiency liquid chromatography

The invention discloses a mobile phase for separating levodopa in broad beans in high efficiency liquid chromatography. The mobile phase contains, by volume percent: 69-97% of 0.1% formic acid, 2-30% of acetonitrile and 1-10% of 0.1mol / L acetic acid. Sediment is prevented from being generated by using acetic acid to replace phosphate buffer fluid, and damage to a pump system is reduced. The mobile phase has no damage to the pump system of a high efficiency liquid chromatograph after being used for a long time. The formic acid can be completely dissolved in acetonitrile-formic acid-water with any proportion at any proportion, no sediment is generated, and the pump system cannot be damaged and is good in condition in year-and-year use. When used for isocratic elution, the mobile phase is simple to operate, time-saving, good in repeatability and easy to repeat.
Owner:CROP RES INST OF FUJIAN ACAD OF AGRI SCI

Method for rapidly and simultaneously determining contents of crocin-1, crocin-2, crocin-3 and crocin-4

The invention discloses a method for rapidly and simultaneously determining the content of crocin-1, crocin-2, crocin-3 and crocin-4. The method comprises the following steps: 1) preparing a reference substance solution; (2) preparing a test solution; 3) loading the sample on a chromatographic column, and using Agilent Poroshell 120 EC-C18 (2.7 [mu] m, 3 * 150 mm) as the chromatographic column; acetonitrile is used as a mobile phase A, 0.1% acetic acid water is used as a mobile phase B, and gradient elution is performed: 24%-25.5% of A and 76%-74.5% of B are performed for 0-9 min; in 9-15 min, 25.5%-30% of A is adopted, and 74.5%-70% of B is adopted; 30%-35% of A and 70%-65% of B are added in 15-18 min; 18-26 min, 35%-40% of A and 65%-60% of B are added; in 26-28 min, 40%-24% of A and 60%-76% of B are added; the flow rate is 0.4 ml / min; the detection wavelength of the ultraviolet detector is 440 nm; the column temperature is 30 DEG C; the sample size is 5 microliters; according to the method, simultaneous determination of crocin-1, crocin-2, crocin-3 and crocin-4 is achieved, the method is simple and high in accuracy, the detection time is greatly shortened, and the separation and identification efficiency of different components of saffron is improved.
Owner:CENT SOUTH UNIV

A method for the detection of nicotine optical isomers in snus by normal phase liquid chromatography-tandem mass spectrometry

Provided is a method for detecting nicotine optical isomers in buccal tobacco by using normal-phase liquid chromatography-tandem mass spectrometry. The method is characterized in that firstly, nicotine in the buccal tobacco is extracted, a chiral chromatographic column is adopted to separate the nicotine optical isomers, a post-column high-pressure infusion pump introduces isopropanol and conducts splitting, assay determination is conducted in combination with the tandem mass spectrometry, and therefore the sensitive detection and the separation of S-(-)-nicotine and R-(+)-nicotine are achieved. The method has the advantages that by the adoption of the post-column high-pressure infusion pump for introducing the isopropanol and conducting the splitting, the volume of a non-polar solvent added into a mass spectrometer is reduced, the volume of the polar solvent isopropanol is compensated at the same time, the ionization efficiency is improved, so that requirements of liquid chromatography-tandem mass spectrometry analysis are met, and the sensitivity of the analysis is improved; compared with current methods, the chromatographic separation degree of the two nicotine optical isomers is high, wherein retention time difference between the two nicotine optical isomers is one minute; the analysis time is short, wherein only seventeen minutes are needed.
Owner:ZHENGZHOU TOBACCO RES INST OF CNTC

Method for detecting cetilistat in weight-losing health-care product

The invention relates to a method for detecting cetilistat in a weight-losing health-care product. The method comprises the following steps: providing a reference substance solution, wherein a reference substance in the reference substance solution contains cetilistat; taking a weight-losing health-care product sample, extracting with methanol, collecting an extracting solution, and preparing a test solution; and detecting the reference solution and the test solution by adopting a high performance liquid chromatography-tandem mass spectrometry method, and determining whether the weight-losing health-care product sample contains the cetilistat or / and the content of the cetilistat according to a detection result. According to the method disclosed by the invention, the separation and detection of the cetilistat in the weight-losing health-care product are realized by adopting a proper extraction solvent and matching with proper detection conditions, the technical blank of the detection of the cetilistat in the weight-losing health-care product is filled, and a theoretical basis is laid for applying a high performance liquid chromatography-tandem mass spectrometry technology to the detection of the cetilistat in the weight-losing health-care product.
Owner:GUANGZHOU INSPECTION TESTING & CERTIFICATION GRP CO LTD

Biogenic amine detection method based on time-resolved dynamic thermal desorption ion mobility spectrometry

The invention provides a biogenic amine detection method based on time-resolved dynamic thermal desorption ion mobility spectrometry, which adopts a thermal desorption sampler to realize time-resolved sample introduction of different biogenic amines based on different thermal desorption characteristics of various biogenic amines; meanwhile, reagent molecule-assisted positive ion photoionization ion mobility spectrometry is adopted for detecting the biogenic amines, and the detection sensitivity and recognition accuracy of the biogenic amines are improved through reagent molecule screening, so that the simultaneous rapid detection of various biogenic amines is realized. The method provided by the invention can realize simultaneous accurate quantification of multiple mixtures, and has the advantages of high sensitivity, fast detection speed and portable instrument.
Owner:DALIAN POLYTECHNIC UNIVERSITY

A kind of detection method of phthalates

The invention discloses a detection method of phthalate matters. The detection method comprises the following steps: firstly carrying out elution by virtue of an ultra-high performance combined-phase chromatograph, wherein the elution conditions are as follows: the sample feeding quantity is 0.5-5 microliters, a stationary phase of a chromatographic column is a C18 filler, a mobile phase A is supercritical CO2, a mobile phase B is acetonitrile, the temperature of the chromatographic column in the detection process is maintained at 45-65 DEG C, and the column flow rate is 1.0mL / min-2.0mL / min; and detecting the eluted components by virtue of a diode array detector, a mass spectrometry detector or a tandem mass spectrometry detector, wherein the detection wavelength of a diode array is 220nm-250nm, and the detection mass numbers of the mass spectrometry detector and the tandem mass spectrometry detector are 40au-500au. By virtue of the detection method, the separation detection of multiple phthalates can be realize within 10 minutes, the detection efficiency is high, and the error rate of a result is less than 10%; and the use amount of an organic solvent is greatly reduced, so that the detection method is relatively environmentally friendly.
Owner:CHONGQING ACAD OF METROLOGY & QUALITY INST
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