The invention belongs to the technical field of measurement, and particularly relates to a multimode fiber-based method and a multimode fiber-based system for simultaneously measuring temperature and strain. The system comprises a laser device, a first coupling device, a polarization controller, an electro-optical modulator, a pulse generator, a first optical amplifier, a first circulator, a first optical grating, a multimode circulator, a multimode optical fiber, a second optical amplifier, a second circulator, a second optical grating, a second coupler, a polarization scrambler, a photoelectric detector, a data application and processing module and a computer display module; by measuring two modes with different brillouin frequency shift-temperature coefficient and brillouin frequency shift-strain coefficient of the multimode optical fiber, a coefficient matrix is formed to realize the simultaneous measurement of the temperature and strain, the cross sensitivity problem in brillouin distribution type optical fiber sensing can be solved, the measurement precision is high, the positioning is accurate, and the cost is low.