Preparation method of intestinal flora gel for flora transplantation
A technology of intestinal flora and gel, which is applied in the direction of biochemical equipment and methods, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problem of strong fluidity of flora suspension, bacterial The group cannot be fully colonized and affects the treatment effect, etc., and achieves the effects of good stability, easy storage, and increased residence time
Pending Publication Date: 2022-05-13
厦门承葛生物科技有限公司
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[0003] At present, transplantation by bacterial suspension is the main method of transplantation. However, bacterial suspension has strong fluidity and a short retention time in the human body. The bacterial flora cannot be fully colonized, which will affect the clinical therapeutic effect.
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[0026] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments It is a part of embodiments of the present invention, but not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention. It should be noted that, in the case of no conflict, the embodiments in the present application and the features in the embodiments can be combined arbitrarily with each other.
[0027] The technical solutions of the present invention will be further described below in conjunction with the accompanying drawings and embodiments.
[0028] Such a...
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The invention provides the preparation method of the intestinal flora gel for flora transplantation. Compared with bacterial liquid, the flora gel prepared by the preparation method has the advantages of high viscosity, easiness in preparation and convenience in storage. Tests show that the stability is better after the culture medium is stored at-20 DEG C for 30 days, and the flora abundance is not greatly changed. Especially for some special patients in flora transplantation clinical treatment, the composition can be popularized and used as a dosage form for prolonging the staying time of the flora in the intestinal tract, and the treatment effect is improved.
Description
technical field [0001] The invention relates to the technical field of flora transplantation, in particular to a method for preparing an intestinal flora gel used for flora transplantation. Background technique [0002] There are about 10 trillion microorganisms in the human digestive tract, including more than 1,000 kinds of bacteria. They perform important functions in the host body, such as preventing the invasion of pathogens, promoting digestion and nutrient absorption, synthesizing vitamins and activating the immune system. In addition, the gut and the central nervous system communicate and interact closely through the release of signaling molecules, so gut microbes also have the potential to affect our brain development and behavior. As an effective means of rebuilding intestinal flora, flora transplantation has been used in clinical treatment and exploratory research of various flora-related diseases, such as severe diarrhea, CDI, ulcerative colitis, irritable bowel ...
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IPC IPC(8): A61K9/06A61K35/741A61K47/36A61P1/00C12Q1/06C12Q1/6869
CPCA61K9/06A61K35/741A61K47/36A61P1/00C12Q1/06C12Q1/6869C12Q2535/122
Inventor 肖传兴李源涛谭文章陈章然林檀林昊张程张帮周崔玲玲
Owner 厦门承葛生物科技有限公司