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Illuminating device for biological tissue on-line three-dimensional imaging system

A technology of three-dimensional imaging and biological tissue, applied in the direction of lighting devices, lighting auxiliary devices, non-electric lighting devices, etc., can solve the problem that light cannot be converged, and achieve the effect of improving accuracy

Pending Publication Date: 2022-07-29
杭州准星医学科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The present invention provides an illumination device for an online three-dimensional imaging system of biological tissue, aiming to solve the problem of linear return along the incident direction during the three-dimensional reconstruction of the sample after the light emitted by the illumination device of the three-dimensional imager in the prior art is refracted. , the problem that the returned light cannot converge to one point

Method used

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  • Illuminating device for biological tissue on-line three-dimensional imaging system
  • Illuminating device for biological tissue on-line three-dimensional imaging system
  • Illuminating device for biological tissue on-line three-dimensional imaging system

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Experimental program
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Effect test

Embodiment 1

[0044] see figure 1 and figure 2 , an illuminating device for a biological tissue online three-dimensional imaging system, comprising a light source and a mounting frame 1; the light source is arranged on the mounting frame 1;

[0045] A plurality of light-emitting points 2 arranged in a circular array are arranged on the mounting frame 1 or around the mounting frame 1; Both are covered with the same point as the monitoring point directly below the center of the annular array of several light-emitting points.

[0046] In order to achieve better illumination intensity, on the basis of the above solution, the central axis of the light beam irradiated by the light source at each light-emitting point passes through the monitoring point.

[0047]In the biological tissue online three-dimensional imaging system, the point where each beam of light passes is the monitoring point where the sample to be detected is placed, and the monitoring point is located directly above the image s...

Embodiment 2

[0063] see Figure 12 , the difference from Embodiment 1 is that the light source includes a driving assembly, a rotating bracket 8 and an LED lamp 9 or a laser light fixed on the rotating bracket; the rotating bracket 8 is connected to the output end of the driving assembly; the light-emitting point It is arranged around the rotating bracket 8. When the rotating bracket rotates, the LED light 9 or the laser light passes through the light-emitting point in sequence and emits a light beam 10 at the light-emitting point. The drive assembly includes a drive motor 6 and a reduction box 7 (gear reduction); Figure 12 The points through which the light beams 10 all pass are the monitoring points 11 for placing the sample.

[0064] The LED light or laser light is controlled by the controller (Raspberry Pi, microcontroller, DSP chip, FPGA chip or computer) to control the switch of the LED light or laser light, and emit light beams at each light-emitting point.

Embodiment 3

[0066] The difference from the other embodiments is that the light source includes a terminal device with a display screen, the light-emitting points are arranged on the display screen, and the display screen emits a light beam by sequentially lighting each light-emitting point, and The rest of the display is dimmed as each light-emitting point emits a beam of light. The terminal device may be a terminal device with a display screen such as a tablet computer and a mobile phone.

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Abstract

The invention provides a lighting device for a biological tissue on-line three-dimensional imaging system, and aims to solve the problem that in the prior art, after light emitted by a lighting device of a three-dimensional imager is refracted, when a sample is linearly transmitted back in the incident direction in the three-dimensional reconstruction process, the transmitted-back light cannot be converged to one point. A lighting device for a biological tissue on-line three-dimensional imaging system comprises a light source and a mounting frame. The light source is arranged on the mounting frame; a plurality of luminous points which are arranged in an annular array are arranged on the mounting frame or around the mounting frame; the light source sequentially irradiates light beams at all the light-emitting points arranged in the annular array, and each light beam passes through one point under the center of the annular array of the multiple light-emitting points. As the light-emitting points are arranged in the annular array and the light beams pass through one point, when the refracted light rays are returned and reconstructed along the incident direction, the returned light rays still converge to one point, namely, the sample points are recovered.

Description

technical field [0001] The invention belongs to the technical field of biological tissue monitoring, in particular to an illuminating device for a biological tissue online three-dimensional imaging system. Background technique [0002] At present, when monitoring biological tissues (biological tissues include organoids, cell clusters, etc., where organoids are multicellular clusters formed by three-dimensional culture of stem cells or tumor cells in vitro), the monitoring equipment with better imaging effect is mainly for The three-dimensional imager for monitoring cell clusters, because the current three-dimensional imager's lighting device luminous point arrangement mainly includes square grid arrangement and biaxial arrangement; when the three-dimensional imager performs three-dimensional reconstruction imaging, it is The light is transmitted back along the incident direction after being refracted, and the image acquired by the image sensor is reconstructed three-dimensio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/01F21V19/00F21V1/00H05B45/00F21V21/30F21Y115/10
CPCG01N21/01F21V19/001F21V1/00F21V21/30H05B45/00G01N2201/061G01N2201/062F21Y2115/10
Inventor 王一飞王运生
Owner 杭州准星医学科技有限公司