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Chinese medicine preparation for treating sepsis and its preparation method

A traditional Chinese medicine preparation and sepsis technology, which is applied in the direction of medical formula, medical preparations containing active ingredients, antibacterial drugs, etc., to achieve the effect of definite curative effect, reduce the fatality rate, and enhance the effect of antagonizing endotoxin

Inactive Publication Date: 2005-02-23
TIANJIN CHASE SUN PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For the treatment of this disease, although modern medicine can control the infection, it has no good strategy for the release and toxicity of endotoxin and inflammatory mediators after infection, so the mortality rate does not decrease.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0115] Preparation of injections

[0116] prescription

[0117] Safflower 100g Red Peony 100g Chuanxiong 100g

[0118] Salvia 100g Angelica 100g

[0119] The above medicines are extracted and refined, and the total amount of 4.5% glucose powder for injection is added to prepare 1,000ml injection.

[0120] Preparation Process

[0121] Safflower percolation refining process

[0122] Percolation

[0123] Weigh the qualified safflower according to the prescription and place it in an appropriate container, moisten it with 30% ethanol for 6 hours, put it in the percolation slip, and soak it in accordance with the percolation method specified on page 13 of the appendix of the Chinese Pharmacopoeia 2000 edition , Oozing. When the collected percolate is about 4-5 times the volume of the medicine material, stop receiving it.

[0124] refined

[0125] Add 95% ethanol to the percolation solution to make the alcohol content reach 70%, refrigerate and stand for 48 hours before filtering. The co...

Embodiment 2

[0145] Tablet preparation

[0146] prescription

[0147] Safflower 100g Red Peony 100g Chuanxiong 100g

[0148] Salvia 100g Angelica 100g

[0149] Preparation Process

[0150] Safflower percolation refining process

[0151] Percolation

[0152] Weigh the qualified safflower according to the prescription and place it in a suitable container, moisten it with 30% ethanol for 6 hours, put it in the percolation slip, and soak it in accordance with the percolation method specified on page 13 of the appendix of the Chinese Pharmacopoeia 2000 edition , Oozing. When the collected percolate is about 4-5 times the volume of the medicine material, stop receiving it.

[0153] refined

[0154]Add 95% ethanol to the percolation solution to make the alcohol content reach 70%, refrigerate and stand for 48 hours before filtering. The co-liquid was decompressed to recover the ethanol until it was exhausted and concentrated to the same volume as the amount of the drug material. Then add 95% ethanol t...

Embodiment 3

[0168] Preparation of oral liquid

[0169] prescription

[0170] Safflower 100g Red Peony 100g Chuanxiong 100g

[0171] Salvia 100g Angelica 100g

[0172] Preparation Process

[0173] Safflower percolation refining process

[0174] Percolation

[0175] Weigh the qualified safflower according to the prescription and place it in a suitable container, moisten it with 30% ethanol for 6 hours, put it in the percolation slip, and soak it in accordance with the percolation method specified on page 13 of the appendix of the Chinese Pharmacopoeia 2000 edition , Oozing. When the collected percolate is about 4-5 times the volume of the medicine material, stop receiving it.

[0176] refined

[0177] Add 95% ethanol to the percolation solution to make the alcohol content reach 70%, refrigerate and stand for 48 hours before filtering. The co-liquid was decompressed to recover the ethanol until it was exhausted and concentrated to the same volume as the amount of the drug material. Then add 95% ...

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PUM

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Abstract

The present invention relates to Chinese medicine with treating and health care functions and is especially one Chinese medicine preparation prepared with safflower, red peony root, Chuanxiong rhizome, red sage, angelica and other Chinese medicinal materials. It can antagonize endotoxin and tumor necrosis factor inflammation medium, may be used for preventing and treating pyaemia, multi-organ malfunction syndrome and other diseases.

Description

Technical field: [0001] The invention relates to a Chinese medicine preparation with therapeutic and health care effects, in particular to a Chinese medicine preparation made from Chinese medicinal materials such as safflower, red peony root, chuanxiong, salvia miltiorrhiza and angelica. Background technique: [0002] Sepsis syndrome is a comprehensive syndrome of systemic inflammatory reaction caused by severe bacterial infection. In the course of the disease, inflammatory mediators are often activated and released, causing a series of clinical symptoms such as high fever, chills, tachycardia, shortness of breath, skin rash, and mental changes. In severe cases, it can cause shock, diffuse intravascular coagulation, and acute respiratory distress syndrome. And Multiple Organ Dysfunction Syndrome (MODS). Even if appropriate antibiotic treatment is given, the fatality rate is still high, which is a worldwide problem that has long plagued the medical community. Traditional Chinese m...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61P31/04
Inventor 姚小青张长海刘培勋
Owner TIANJIN CHASE SUN PHARM CO LTD