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Yunnan begonia herb drip pill and its preparation method

A technology of Shanhaitang dripping pills and Shanhaitang, which is applied in pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve problems that are not conducive to improving patients' ability to seek medical treatment, bioavailability of the first-pass effect of the liver and intestines, and adverse overall health Level and other issues, to achieve the effect of benefiting labor protection and environmental protection, improving bioavailability, and drug safety

Inactive Publication Date: 2007-05-23
北京博智绿洲医药科技有限公司
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  • Abstract
  • Description
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  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
In addition, conventional oral dosage forms, such as tablets, capsules, granules (infusions), etc., due to the granulation process in the preparation process, will generate relatively large dust pollution, which will cause health problems to the staff to a certain extent. harm, and also cause some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
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Effect test

Embodiment Construction

[0027] Now with several groups of specific examples, the preparation method of the Begonia dripping pills of the present invention will be further described.

[0028] [Group 1: Trials with a single substrate]

[0029] 1: Raw materials: According to [Preparation Method 1], the extract dry powder containing the active pharmaceutical ingredients of the traditional Chinese medicine Begonia chinensis is firstly prepared for use;

[0030] 2. Substrate: polyethylene glycol 1000 , polyethylene glycol 4000 , polyethylene glycol 6000 , polyethylene glycol 10000 , polyethylene glycol 20000 , Span 40, polyoxyl 40 stearate, poloxamer, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac;

[0031] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0032] 4. Prepare according to the process given in [Preparation Method] 4-7, and you can get Shanhaitang dripping pills with different specifications.

[0033] [test results]

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Abstract

A Chinese medicine in the form of dripping pill for treating rheumatic arthritis, rheumatoid arthritis, chronic arthritis, lupus erythematosus, etc is prepared from Yunnan begonia herb and medicinal carrier. Its preparing process is also disclosed.

Description

technical field [0001] The present invention relates to a kind of medicinal composition which has the functions of expelling wind and dehumidification, soothing pan and activating collaterals, clearing away heat and detoxifying, and is used for the treatment of rheumatoid arthritis, rheumatoid arthritis, chronic arthritis and lupus erythematosus. An oral preparation of a pharmaceutical composition prepared from crabapple as a raw material. Background technique [0002] According to the preparation method given in the ministerial drug standard WS3-B-0755-91, the Begonia Tablets are prepared, which has the functions of expelling wind and dampness, soothing the pan and activating collaterals, clearing away heat and detoxification, and is used for rheumatoid arthritis. Oral tablets for the treatment of rheumatoid arthritis, chronic arthritis, lupus erythematosus and other diseases have been clinically verified and have definite curative effects. They are commonly used drugs for ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/185A61P29/00A61P19/02A61K125/00
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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