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Dispersion tablet containing ginkgo leaf extract

A technology of extracts and dispersible tablets, applied in the field of dispersible tablets containing ginkgo biloba extract, which can solve the problems of not making dispersible tablets

Active Publication Date: 2004-09-15
JIANGSU CHENPAI PHARM GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0033] Although formulations based on Ginkgo biloba extract have existed, they have not yet been made into dispersible tablets

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0083] Prepare 4000 dispersible tablets containing Ginkgo biloba medicinal material extract (each tablet contains 0.1g extract): 400g extract, 560g microcrystalline cellulose, 280g sodium carboxymethyl starch, 28g polyvinylpyrrolidone, 28g micronized silica gel. Fully mix the extract with microcrystalline cellulose, sodium carboxymethyl starch and some micropowder silica gel, pass through 80 sieves, add 30% ethanol solution containing polyvinylpyrrolidone, stir evenly, make granules, granulate after drying, Add another part of micropowder silica gel to mix with the granules, and press to shape with a tablet machine. The tablet is then continuously sprayed with film-forming material (containing conventional polymer-containing coating materials) in a suitable apparatus until the coating is acceptable.

Embodiment 2

[0085] Prepare 4000 dispersible tablets containing Ginkgo biloba medicinal material extract (each tablet contains 0.025g extract): 100g extract, 840g starch, 120g low-substituted hydroxypropyl cellulose, 12g gelatin, 12g magnesium stearate. Fully mix the extract and starch, pass through 80 sieves, add an aqueous solution containing gelatin, stir evenly, make granules, granulate after drying, add low-substituted-hydroxypropyl cellulose and magnesium stearate and mix well with the granules , pressed into shape with a tablet press. The tablet is then continuously sprayed with film-forming material (containing conventional polymer-containing coating materials) in a suitable apparatus until the coating is acceptable.

[0086] The taking method of the tablet of the present invention is: oral administration, 4 to 10 tablets at a time, 3 times a day.

Embodiment 3

[0088] Prepare 4000 dispersible tablets containing Ginkgo biloba medicinal material extract (each tablet contains 0.225g extract): 900g extract, 540g microcrystalline cellulose, 200g sodium carboxymethyl starch, 20g polyvinylpyrrolidone, 50g micronized silica gel, sodium saccharin 50g, coffee essence 9g. Fully mix the extract with microcrystalline cellulose, part of sodium carboxymethyl starch and part of micropowder silica gel, pass through 80 sieves, add 50% ethanol solution containing polyvinylpyrrolidone, stir evenly, make granules, and granulate after drying , adding another part of sodium carboxymethyl starch, micropowder silica gel, sodium saccharin, coffee essence and granules, mixing them evenly, and pressing them into shape with a tablet press. The tablet is then continuously sprayed with film-forming material (containing conventional polymer-containing coating materials) in a suitable apparatus until the coating is acceptable.

[0089] The taking method of the tabl...

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PUM

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Abstract

The present invention relates to a dispersion tablet preparation containing ginkgo leaf extract and its preparation method, in which for one weight portion of extract said dispersion tablet also contains 0.5-10 weight portions of filling agent, 0.1-5 weight portions of disintegrant, 0.01-0.1 weight portion of lubricant and 0.01-0.1 weight portion of adhesive. Said invented medicine dispersion tablet mainly is used for curing diseases of cardiovascular system, and it is characterized by that it is placed in the warm water with 37 deg.C, it can be completely disintegrated within 3 min.

Description

technical field [0001] The invention belongs to a Chinese herbal medicine extract preparation, in particular to a dispersible tablet containing ginkgo leaf extract. Background technique [0002] Ginkgo biloba leaves are also known as ginkgo leaves, Gongsun leaves and so on. It is the dry leaves of the Ginkgo biloba tree. "Compendium of Materia Medica" records that its nature and flavor are sweet, bitter and astringent, and it enters the lung and kidney channels. It has the functions of relieving asthma, relieving cough, relieving turbidity, and reducing stool. Its medicinal active ingredients are mainly flavonoids and ginkgolides, etc., referred to as Ginkgo biloba extract. [0003] Ginkgo biloba extract is an effective active ingredient extracted from the leaves of Ginkgo biloba plant, which is a special plant in my country. According to "Materia Medica", Ginkgo biloba has the functions of soothing the lungs and relieving asthma, stopping enuresis an...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61P9/00A61P9/10
Inventor 李崇明黄志军翟莉曾庆恢徐绍新王永平石召华
Owner JIANGSU CHENPAI PHARM GRP CO LTD
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