Application of chitosan and ramification in lkjpreparing product for anti Helicobacter Pylori

Abstract

An application of chitosand and its delivative in preparing the medicine for treating the gastritis, gastric ulcer and duodenal ulcer, which are caused by pylorospirobacillus, is disclosed. Its action mechanism is also disclosed.

Description

technical field [0001] The invention relates to the field of pharmaceutical application inventions, in particular to an application of chitosan in preparing anti-helicobacter pylori products. Background technique [0002] Chitosan (Chitosan), also known as chitosan, the chemical name is polymerized β-(1,4)-2-amino-D-glucose, that is, deacetylation at the 2nd position of chitin to expose -NH 2 The product formed by the gene is a high-molecular-weight straight-chain polysaccharide with the molecular formula (C 6 h 11 NO 4 )n, decomposes at about 185°C. Its average molecular mass is 1MDa, and its molecular chain length is about 5000 units, but in practical applications, its molecular weight, that is, the degree of polymerization, varies with different needs. Chitosan is white or light yellow powder, insoluble in neutral and alkaline aqueous solutions and most organic solvents, soluble in monovalent inorganic acids and organic acids. Its solubility depends on the degree of ...

AI Technical Summary

Problems solved by technology

Although there are multiple drug combination therapies for the eradication of Helicobacter pylori, there are still many problems, such as the emergence of drug-resistant strains of Helicobacter pylori, expensive drugs, large side effects, and poor patient compliance.

Therefore, there is no ideal treatment plan that is simple, effective, economical, non-toxic and side effects, good patient compliance, and low drug resistance rate.