Application of chitosan and ramification in lkjpreparing product for anti Helicobacter Pylori
An anti-Helicobacter pylori and chitosan derivative technology is applied in the directions of antibacterial drugs, medical preparations containing active ingredients, drug combinations, etc., and can solve problems such as large side effects, low drug resistance rate, and high drug prices.
Inactive Publication Date: 2005-08-31
谢勇 +1
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- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Although there are multiple drug combination therapies for the eradication of Helicobacter pylori, there are still many problems, such as the emergence of drug-resistant strains of Helicobacter pylori, expensive drug
Method used
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Experimental program
Comparison scheme
Effect test
Embodiment 1
[0173] With known method in this technical field, take carboxymethyl chitosan as raw material, make chitosan tablet.
Embodiment 2
[0175] The chitosan oral liquid is made from a 70% deacetylated chitosan solution with a pH value of 4 or 5 and a concentration of 1.5% as a raw material by a method known in the art.
Embodiment 3
[0177] Using a method known in the art, the chitosan tablet is made from an 88.5% deacetylated chitosan solution with a pH value of 4 and a concentration of 2% as a raw material.
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An application of chitosand and its delivative in preparing the medicine for treating the gastritis, gastric ulcer and duodenal ulcer, which are caused by pylorospirobacillus, is disclosed. Its action mechanism is also disclosed.
Description
technical field [0001] The invention relates to the field of pharmaceutical application inventions, in particular to an application of chitosan in preparing anti-helicobacter pylori products. Background technique [0002] Chitosan (Chitosan), also known as chitosan, the chemical name is polymerized β-(1,4)-2-amino-D-glucose, that is, deacetylation at the 2nd position of chitin to expose -NH 2 The product formed by the gene is a high-molecular-weight straight-chain polysaccharide with the molecular formula (C 6 h 11 NO 4 )n, decomposes at about 185°C. Its average molecular mass is 1MDa, and its molecular chain length is about 5000 units, but in practical applications, its molecular weight, that is, the degree of polymerization, varies with different needs. Chitosan is white or light yellow powder, insoluble in neutral and alkaline aqueous solutions and most organic solvents, soluble in monovalent inorganic acids and organic acids. Its solubility depends on the degree of ...
Claims
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Patent Timeline
Login to view more IPC IPC(8): A61K31/722A61K45/06A61P1/04A61P31/04
Inventor 谢勇周南进周小江吕农华
Owner 谢勇
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