Polygala dropping balls and preparation thereof

Abstract

An expectorant in the form of dripping pill is prepared from polygala root. It is based on the polygala syrup.

Description

technical field [0001] The invention relates to a pharmaceutical composition for the treatment of symptoms such as coughing up phlegm, in particular to an oral drop pill preparation of the pharmaceutical composition formulated on the basis of traditional Chinese medicine polygala syrup. Background technique [0002] According to the national drug standard WS 3 - Polygala syrup prepared according to the formula and extraction process given in B-2140-96 is an expectorant. Syrup preparations for the treatment of symptoms such as coughing up phlegm, have been clinically verified for many years, with stable quality and definite curative effect. They are commonly used pharmaceutical preparations for clinical and family use to treat the above diseases. [0003] The following is the drug standard WS 3 -The formula and extraction process of polygala syrup given in B-2140-96: [0004] Prescription: Polygala extract 200ml, concentrated ammonia solution 4ml; [0005] Preparation met...

AI Technical Summary

Problems solved by technology

[0011] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect

Syrup drugs also have the disadvantages of low drug content, difficulty in taking and measuring accurately, and inconvenient taking and carrying.

In addition, conventional oral dosage forms, such as syrup, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also pollute the environment. cause some pollution

Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.