Hairy holly root drip pill and its preparation method
A technology of Maodongqing and dripping pills, which is applied in the directions of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the bioavailability of the first-pass effect of the liver and intestines, is not conducive to improving the ability of patients to seek medical treatment, and is not conducive to the overall health level, etc. problems, to achieve the effect of benefiting labor protection and environmental protection, improving bioavailability, and drug safety
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[0025] Now with several groups of specific examples, the preparation method of Maodongqing dripping pills of the present invention will be further described.
[0026] Group 1: Tests with a single matrix
[0027] 1. Raw materials: according to the preparation method 1, the dry powder containing the active pharmaceutical ingredient of the traditional Chinese medicine Maodongqing is pre-prepared for use;
[0028] 2. Substrate: polyethylene glycol (1000、2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc.;
[0029] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;
[0030] 4. Prepare according to the process given in [Preparation Method] 4-7 to obtain Maodongqing dripping pills of different specifications.
[0031] [test results]
[0032] Experiment 1: In order to observe the difference in quali...
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