Hairy holly root drip pill and its preparation method

A technology of Maodongqing and dripping pills, which is applied in the directions of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the bioavailability of the first-pass effect of the liver and intestines, is not conducive to improving the ability of patients to seek medical treatment, and is not conducive to the overall health level, etc. problems, to achieve the effect of benefiting labor protection and environmental protection, improving bioavailability, and drug safety

Inactive Publication Date: 2005-10-26
北京博智绿洲医药科技有限公司
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  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicines, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic first-pass effect and low bioavailability after taking. Thus affecting the efficacy of the drug, and directly affecting the therapeutic effect
In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0025] Now with several groups of specific examples, the preparation method of Maodongqing dripping pills of the present invention will be further described.

[0026] Group 1: Tests with a single matrix

[0027] 1. Raw materials: according to the preparation method 1, the dry powder containing the active pharmaceutical ingredient of the traditional Chinese medicine Maodongqing is pre-prepared for use;

[0028] 2. Substrate: polyethylene glycol (1000、2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc.;

[0029] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0030] 4. Prepare according to the process given in [Preparation Method] 4-7 ​​to obtain Maodongqing dripping pills of different specifications.

[0031] [test results]

[0032] Experiment 1: In order to observe the difference in quali...

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PUM

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Abstract

A Chinese medicine in the form of dripping pill for treating coronary arteriosclerotic heart disease, thromboangiitis obliterans, central retinitis, infantile pneumonia, etc is prepared from pubescent holly root and medicinal carrier. Its preparing process is also disclosed.

Description

technical field [0001] The present invention relates to a kind of medicine composition that has expansion blood vessel and antibacterial and anti-inflammatory effect, is used for treating coronary artery disease heart disease, thromboangiitis obliterans, and is used for central retinitis, children's pneumonia etc. Dongqing is a raw material of traditional Chinese medicine, and it is an oral preparation of a pharmaceutical composition prepared together with a pharmaceutically acceptable carrier as a matrix. Background technique [0002] According to the ministerial drug standard WS 3 - Maodongqing Capsule prepared by the preparation method given in B-1290-93 is an oral preparation prepared from Maodongqing as a raw material of traditional Chinese medicine. It has blood vessel expansion and antibacterial and anti-inflammatory effects, and is used for the treatment of coronary arteriosclerosis Cardiac heart disease, thromboangiitis obliterans, and oral capsules for central ret...

Claims

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Application Information

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Patent Type & Authority Applications(China)
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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