Nano silver bionic dressing and its preparing method

A technology of nano-silver and nano-silver particles, applied in medical science, bandages, absorbent pads, etc., can solve the problems of difficult clinical promotion and application, high price, etc., and achieve the functions of lasting anti-infection ability, reducing dosage, and accelerating wound healing Effect

Inactive Publication Date: 2006-05-24
NANTONG UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to its high price, it is not e

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Preparation Process:

[0048] §1. Preparation of nano-silver particles:

[0049] (1) 1×10 -3 mol / LAgNO 3 Solution: Accurately weigh 0085gAgNO 3 Place in a beaker, dissolve with sub-boiling water, transfer to a 500mL volumetric flask, and make to volume. Filter to remove impurities and add to the container that has been rinsed with sub-boiling water;

[0050] (2) 10mg / mLNa 3 C 6 h 5 o 7 2H 2 O solution: accurately weigh 0.1gNa 3 C 6 h 5 o 7 2H 2 O was placed in a beaker and dissolved with sub-boiling water, transferred to a 10mL volumetric flask, and made to volume. filter to remove impurities;

[0051] (3) Heating and stirring the AgNO 3 Solution container, after boiling, drop Na 3 C 6 h 5 o 7 2H 2 O solution, react for about 30 minutes, remove from the heat source, and cool naturally to obtain a solution of silver nanoparticles with a size of 10-100nm.

[0052] §2. Preparation of chitosan film:

[0053] (1) 0.5% acetic acid solution: take 0.5mL g...

Embodiment 2

[0066] §1. Preparation of nano-silver particles:

[0067] (1) 1×10 -3 mol / LAgNO 3 Solution: Accurately weigh 0.085gAgNO 3 Place in a beaker, dissolve with sub-boiling water, transfer to a 500mL volumetric flask, and make to volume. Filter to remove impurities and add to the container that has been rinsed with sub-boiling water;

[0068] (2) 10mg / mL Na 3 C 6 h 5 o 7 2H 2 O solution: accurately weigh 0.1gNa 3 C 6 h 5 o 7 2H 2 O was placed in a beaker and dissolved with sub-boiling water, transferred to a 10mL volumetric flask, and made to volume. filter to remove impurities;

[0069] (3) Heating and stirring the AgNO 3 Solution container, after boiling, drop Na 3 C 6 h 5 o 7 2H 2 O solution, react for about 30 minutes, remove from the heat source, and cool naturally to obtain a solution of silver nanoparticles with a size of 10-100nm.

[0070] §2. Preparation of chitosan film:

[0071] (1) 1% acetic acid solution: take 1mL of glacial acetic acid in a contai...

Embodiment 3

[0084] §1. Preparation of nano-silver particles:

[0085] (1) 1×10 -3 mol / LAgNO 3 Solution: Accurately weigh 0.085gAgNO 3 Place in a beaker, dissolve with sub-boiling water, transfer to a 500mL volumetric flask, and make to volume. Filter to remove impurities and add to the container that has been rinsed with sub-boiling water;

[0086] (2) 10mg / mL Na 3 C 6 h 5 o 7 2H 2 O solution: accurately weigh 0.1gNa 3 C 6 h 5 o 7 2H 2 O was placed in a beaker and dissolved with sub-boiling water, transferred to a 10mL volumetric flask, and made to volume. filter to remove impurities;

[0087] (3) Heating and stirring the AgNO 3 Solution container, after boiling, drop Na 3 C 6 h 5 o 7 2H 2 O solution, react for about 30 minutes, remove from the heat source, and cool naturally to obtain a solution of silver nanoparticles with a size of 10-100nm.

[0088] §2. Preparation of chitosan film:

[0089] (1) 5% acetic acid solution: take 5 mL of glacial acetic acid in a conta...

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Abstract

The present invention discloses a nano silver biological bionic dressing and its preparation method. Said invention utilizes nano technology and self-assembling technology to assemble nano silver particle layer on the chitosan film. Its preparation includes the following steps: (1) preparation of nano silver particles: preparing silver nitrate (Ag NO3) solution, placing said solution in a container, stirring, heating and boiling, then drop-adding sodium citrate (Na3 C6 H5 O7 2H2O) solution, reacting for a certain time, then naturally cooling; (2) preparation of chitosan film: using acetic acid solution to dissolve chitosan, suction-filtering, pouring the suction-filtered solution into culture dish, drying to form film, using sodium hydroxide (No OH) to make treatment, finally using running water to rinse the film; and (3) preparation of nano silver biological bionic dressing: soaking the chitosan film in the nano silver particle solution, utilizing self-assembling technique to make nano silver particles be assembled on the chitosan film so as to obtain the invented product.

Description

technical field [0001] The present invention belongs to the dressing in the medical apparatus and instruments, is the nano-silver biomimetic dressing that utilizes nanotechnology and self-assembly technology to construct, specifically is the biological dressing used for the treatment of wounds and burns, scalds, and wounds in clinical treatment. Further, it is A nano-silver bionic dressing and a preparation method thereof. Background technique [0002] The skin is a barrier to maintain the stability of the internal environment and prevent the invasion of microorganisms. Reconstructing or restoring the skin barrier is the ultimate goal of burn treatment. Before this goal is achieved, an excellent wound covering can temporarily function as a skin barrier and provide an environment conducive to wound healing. An ideal wound covering should have: ①Good adhesion and permeability, and can control water evaporation, with a water evaporation rate similar to that of normal skin; ②Re...

Claims

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Application Information

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IPC IPC(8): A61L15/00A61F13/00
Inventor 顾海鹰张逸鲁双云高文娟黄剑飞朱惠君姜启玉于春梅丁斐何红
Owner NANTONG UNIVERSITY
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