Compound artificial joint with artificial cartilage structure

An artificial joint and artificial technology, applied in the direction of joint implants, joint implants, prostheses, etc., can solve the problems of easy aging, no biological activity, aging and degeneration that cannot be maintained, and achieve a fixed and stable effect

Inactive Publication Date: 2006-06-28
SICHUAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The technical effect of this new design for an artificial joint prosthetic device has been achieved by attaching a special type of material called cushion rubber (CR) inside or outside the knee joint cavity during surgery. This CR helps create space within the damaged area where there are no blood vessels around them while still supporting their weight. By doing so, these devices help prevent damage from external factors like impacts caused when they hit hard objects on one's legs.

Problems solved by technology

This patents describes various technical solutions aimed towards improving the durability and stability of artificial cartils made from high modulus polymers like polytetrafluorocarbon (PTFE). These polymer compositions provide better strength than existing ones but suffer from reduced membrane hydration compared to regular kneading techniques. Additionally, there may exist issues associated with their physical interaction with human hard tissues including inflammations caused by friction forces and potential cell deaths. Chemical fixatives offer advantages over traditional methods while providing more stable fixation results.

Method used

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  • Compound artificial joint with artificial cartilage structure

Examples

Experimental program
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Effect test

preparation example 1

[0036] 2g chitosan powder is dissolved in the 3wt% chitosan solution that is formulated in the dilute acetic acid solution of 2wt% with concentration in 65ml, adds the guanidine hydrochloride solution (wherein BMP weight is 0.04g) of BMP and mixes homogeneously therein. Immerse the macroporous mechanical support unit structure of nano-hydroxyapatite / polyamide 6 with fixed rods and a pore size of 1 to 4 mm into the mixed solution, and in 10 -2 ~10 -1 Make the mixed solution completely fill the pores of the macroporous scaffold under 1 atmospheric pressure, take it out and freeze it at -10°C to -20°C for 24 hours, and then store it at 10 -4 ~10 -3 Freeze-dry for 24-36 hours at 1 atmospheric pressure. Then take it out and immerse it in 10wt% ammonia water for 2 to 6 hours, then wash it repeatedly with deionized water until the pH is about 7, and freeze it at -5°C for 24 hours, -4 ~10 -3 vacuum freeze-drying under 1 atmospheric pressure for 16-24 hours to obtain a composite po...

preparation example 2

[0039] Dissolve 2g of chitosan powder in 65ml of 3wt% chitosan solution prepared with 2wt% dilute acetic acid solution, add 10mg of TGF-β powder therein and stir evenly. Immerse the macroporous mechanical support unit structure of nano-hydroxyapatite / polyamide 66 with fixed rods and a pore size of 1 to 4 mm in the mixed solution, and in 10 -2 ~10 -1 Make the mixed solution completely fill the pores of the macroporous scaffold under 1 atmospheric pressure, take it out and freeze it at -10°C to -20°C for 24 hours, and then store it at 10 -4 ~10 -3 Freeze-dry for 24-36 hours at 1 atmospheric pressure. After taking it out, immerse it in 10wt% ammonia water for 2-6 hours, then wash it repeatedly with deionized water until the pH is about 7, freeze it at -5°C for 24 hours, and then freeze it at -5°C for 24 hours, -4 ~10 -3 vacuum freeze-drying under 1 atmospheric pressure for 16-24 hours to obtain a composite porous support unit.

[0040] Immerse the 1 / 4 length part of the othe...

preparation example 3

[0042] Dissolve 2g of chitosan powder in 65ml of 3wt% chitosan solution prepared with 2wt% dilute acetic acid solution, add 10mg of IGF powder therein and stir evenly. Immerse the macroporous mechanical support unit structure of nano-hydroxyapatite / polyamide 66 with fixed rods and a pore size of 1 to 4 mm in the mixed solution, and in 10 -2 ~10 -1 Make the mixed solution completely fill its pores under 1 atmospheric pressure, take it out and freeze it at -10°C to -20°C for 24 hours, and then store it at 10 -4 ~10 -3 Freeze-dry for 24-36 hours at 1 atmospheric pressure. After taking it out, immerse it in 10wt% ammonia water for 2-6 hours; then wash it repeatedly with deionized water until the pH is about 7, and freeze it at -5°C for 24 hours, and then freeze it at -5°C for 24 hours, -4 ~10 -3 vacuum freeze-drying under 1 atmospheric pressure for 16-24 hours to obtain a composite porous support unit.

[0043] Immerse the 1 / 4 length of the other end of the above-mentioned co...

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Abstract

A composite artificial joint with artificial cartilage structure features that an artificial cartilage structure layer made of polyvinyl alcohol hydrogel is arranged on the end face of a mechanical supporting unit, which may use a composite material structure body made of nano-hydroxy apatite and/or medical high-molecular material and/or porous mechanical supporting structure and contains the chtosan sponge carrying growth factor. The connection end of mechanical supporting unit and base bone has at least one convex fixing structure.

Description

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Claims

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Application Information

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Owner SICHUAN UNIV
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