Compound notoginsen triterpenes puerarin preparation

A technology of panax notoginseng saponins and compound panax notoginseng, which can be used in food preparation, pill delivery, pharmaceutical formulations, etc., can solve the problems of comprehensive curative effect to be improved, and achieve the effect of thrombus formation inhibition and good dose-effect relationship

Inactive Publication Date: 2006-09-27
云南一尧科技开发有限公司
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  • Abstract
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  • Application Information

AI Technical Summary

Problems solved by technology

Although the traditional Chinese medicine of Panax notoginseng saponins (preparation name Xuesaitong) approved for the first time by the Yunnan Provincial Department of Health has certain curative effects on cardiovascular and cerebrovascular diseases, its comprehensive curative effect needs to be improved like puerarin.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] Compound Panax notoginseng saponins and puerarin granules, formula:

[0057] Panax notoginseng saponins: 200g

[0058] Puerarin: 50g

[0059] Sucrose 1000g

[0060] Starch 1500g

[0061] Mannitol 340g

[0062] Dextrin 360g

[0063] Proper amount of ethanol

[0064] Preparation method: Mix the above-mentioned prescription amount of medicine and auxiliary materials, grind into coarse powder to pass 10-20 meshes, granulate according to common granulation method, and pack into 1000 bags. Take one bag each time, 1-2 times a day.

Embodiment 2

[0066] Compound panax notoginseng saponins puerarin dropping pills, formula:

[0067] Panax notoginseng saponins: 35g

[0068] Puerarin 25g

[0069] PEG400 200g

[0070] It is prepared according to the preparation method of ordinary dropping pills, and each pill contains 5-20 mg of active ingredients.

Embodiment 3

[0072] Compound Panax notoginseng saponins and puerarin freeze-dried powder injection, formula:

[0073] Panax notoginseng saponins 45g

[0074] Puerarin 55g

[0075] Mannitol 100g

[0076] Preparation method: Under the condition of 10,000 grades, the qualified drug and auxiliary materials are dissolved in water for injection, and after decolorization and other treatments, add water for injection and dilute to the required volume. Filtration, the filtrate is treated with filter paper and 0.4μm filter membrane, and then filtered with a filter membrane below 0.2μm under the condition of 100 grades. The fine filtrate is sent to the packing machine, packed according to 1~2ml per tube, covered with a slotted lid, sent to the freeze vacuum dryer, quickly cooled to 35°C~40°C, 2~3 hours, and gradually warmed up to 35°C ~45°C (about 10 hours). Tighten the lid, take out the product, tie the lid, pack, inspect, and pass the test to obtain 1,000 sticks of 100 mg compound panax notogin...

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PUM

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Abstract

The present invention is compound total arasaponin-puerain preparation, and features that total arasaponin in 21-82 wt% and puerain in 18-79 wt% as well as proper amount of medicinal or food supplementary material are produced into medicine or food preparation. The compound total arasaponin-puerain preparation has the synergistic effects of regulating blood function, treating cardiac and cerebral vascular diseases, lowering serum total cholesterol and triglyceride, reducing blood viscosity, improving micro circulation, etc.

Description

technical field [0001] The invention relates to a compound preparation containing total saponins of Panax notoginseng and puerarin, which have medical or health care effects on blood circulation. Background technique [0002] Panax notoginseng (also known as Panax notoginseng, Tianqi, southern ginseng) is a plant of the genus Panax of Araliaceae. Its roots, leaves, flowers, etc. have medicinal value, mainly containing notoginseng saponins (content 2% to 14%) and other substances. Research data proves that the total saponins of Panax notoginseng are the active ingredients of Panax notoginseng to promote blood circulation and remove stasis, which can effectively improve the hemodynamics of blood circulation, reduce blood viscosity, lower blood sugar and blood lipids, and prevent the occurrence of vascular inflammation and so on. The notoginseng saponins contained in Panax notoginseng belong to ginseng saponins, and dozens of monomers such as Rg 1 , Rb 1 , notoginsenoside R ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/258A61K9/00A61K9/08A61K9/14A61K9/16A61K9/20A61K9/48A61P9/00A23L1/30A61K31/7048A23L33/105
Inventor 任杨帆
Owner 云南一尧科技开发有限公司
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