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Formula of external-use Chinese medicine for treating ulcerative stomatitis

A technology for oral ulcers and external medicine, applied in the field of medicine, can solve the problems of easy recurrence, poor pain relief, toxic and side effects, and achieve the effects of no toxic side effects, no recurrence, and good pain relief.

Inactive Publication Date: 2006-10-25
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among the external medicines currently used to treat this disease, Western medicines, such as chlorhexidine hydrochloride, compound boric acid solution, lysozyme, etc., mostly aim at preventing secondary infection and alleviating pain. toxic side effects
However, the existing traditional Chinese medicines for external use, such as traditional Chinese patent medicine Bingboran Powder, Yangyin Shengji Powder, etc., have the disadvantage of poor analgesic effect and poor curative effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0009] The preparation method of this medicine for external use is:

[0010] 1) Take asarum, steam distill and extract the volatile oil, add 0.5-2.5 times the volume of the volatile oil in micro-powdered silica gel and mix evenly, pass through a 60-200 mesh sieve to prepare the volatile oil micro-powdered silica gel mixture, and set aside;

[0011] 2) Take Evodia rutaecarpa, add 40-90% ethanol to extract, filter while it is hot, recover the ethanol from the filtrate under reduced pressure, concentrate it into a thick paste, dry it under reduced pressure, crush it through a 60-200 mesh sieve, and prepare Evodia rutaecarpa extract powder for future use ;

[0012] 3) Take the matrix polyethylene glycol (the ratio of matrix weight to Asarum and Evodia rutaecarpa is 0.2-1:1), heat and melt in a water bath, cool to 45-65°C, keep warm, add Evodia rutaecarpa extract powder, volatile oil micro-powder silica gel Stir the mixture evenly, pour it into the mold (the diameter of the mold h...

Embodiment 1

[0076] 1. Take 580g Asarum, add 8 times the amount of water to soak for 1 hour, steam distillation and extraction for 3 hours to obtain volatile oil, add micronized silica gel with 1 times the volume of volatile oil, mix well, pass through a 100-mesh sieve, and set aside.

[0077] 2. Take 580g Evodia rutaecarpa, add 80% ethanol to extract twice, each time for 2 hours, filter while hot, recover ethanol from the filtrate under reduced pressure, concentrate into a thick paste, dry under reduced pressure, crush through a 100-mesh sieve, and set aside.

[0078] 3. Take 374.6g of polyethylene glycol, heat and melt in a water bath, cool to 50-55°C, keep warm, add Evodia rutaecarpa extract powder, volatile oil micro-powder silica gel mixture, stir evenly, pour it into a mold (the diameter of the mold hole is 15mm, the height is 2.5 mm), cooling, demoulding, to obtain tablets, which are placed in the foam-molded PVC die holes, covered with non-woven adhesive tape, and the finished produ...

Embodiment 2

[0080] 1. Take Asarum 870g, add 8 times the amount of water to soak for 1 hour, steam distillation and extraction for 3 hours to obtain volatile oil, add micronized silica gel with 2.0 times the volume of volatile oil, mix well, pass through a 120-mesh sieve, and set aside.

[0081] 2. Take 290g of Evodia rutaecarpa, add 70% ethanol to extract twice, each time for 2 hours, filter while it is hot, recover ethanol from the filtrate under reduced pressure, concentrate into a thick paste, dry under reduced pressure, crush through a 120-mesh sieve, and set aside.

[0082] 3. Take 442.5g of polyethylene glycol, heat and melt in a water bath, cool to 50-55°C, keep warm, add Evodia extract powder, volatile oil micro-powder silica gel mixture, stir evenly, and pour it into a mold (the diameter of the mold hole is 15mm, the height is 2.5mm) mm), cooling, demoulding, to obtain tablets, which are placed in the foam-molded PVC die holes, covered with non-woven adhesive tape, and the finishe...

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Abstract

The present invention discloses a Chinese medicine for external application for effectively curing ulcerative stomatitis. It is made up by using Chinese medicinal materials of asarum and evodia fruit through a certain preparation process.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a formula of traditional Chinese medicine for treating oral ulcers. Background technique [0002] Oral ulcers and recurrent oral ulcers are the most common diseases in oral mucosal diseases, with a high incidence. The theory of traditional Chinese medicine believes that although the disease is born in the mouth, it is closely related to the viscera and meridians. The spleen opens to the mouth, the heart opens to the tongue, the kidney vein connects with the pharynx and connects to the tongue, and the cheeks and gums belong to the stomach and large intestine meridian. Injured by improper diet, fatigue, emotional distress and other factors, resulting in dysfunction of the viscera, heat in the heart and spleen, flaming stomach fire; or deficiency of qi and yin, hyperactivity of fire due to yin deficiency; Fumigation of tongue, can lead to the occurrence of this disease. Among the external...

Claims

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Application Information

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IPC IPC(8): A61K36/754A61P1/02
Inventor 田景奎张琳厉英光李凌军陈赟梁波
Owner ZHEJIANG UNIV
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