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Chinese medicine composition for treating optic atrophy and preparing method therefor

A technology of optic atrophy and composition, which is applied in the direction of drug combination, drug formulation, drug delivery, etc., and can solve problems such as poor effect, complex formula components, and expensive raw materials

Inactive Publication Date: 2006-10-25
BEIJING INST OF OPHTHALMOLOGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no specific and effective treatment for this disease, and a large number of neurotrophic drugs and vasodilators are mainly used clinically, and the effect is not good
Chinese patents have disclosed traditional Chinese medicines for the treatment of optic atrophy, such as CN1544072, CN1119944, and CN1130518. The formulas of these patents have not been successfully used in clinical practice, and the formula components are complex and the raw materials are expensive

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] [embodiment 1] capsule preparation of Chinese medicine composition of the present invention

[0037] a) Add 1.5 g of Acorus calamus with 8 times the amount of water, soak for 4 hours, extract the volatile oil with steam distillation for 8 hours, store the volatile oil for later use, collect the distilled aqueous solution in another device, and obtain solution 1;

[0038] b) add 10 times the amount of water to a) traditional Chinese medicine dregs, 4 g of Chinese wolfberry, 3 g of Ligustrum lucidum, and 3 g of Eclipta chinensis, decoct three times for 1 hour each time, and combine the decoctions to form solution 2;

[0039] c) Combine Solution 1 and Solution 2, filter, concentrate to a liquid medicine with a relative density of 1.08-1.10 (55° C.), spray dry to obtain a fine powder, add 0.15 g of Ginkgo biloba extract, and then add appropriate amount of sucrose and starch, Or add an appropriate amount of dextrin, mix evenly, make granules by dry method, spray volatile oil...

Embodiment 2

[0040] [embodiment 2] preparation of granules of Chinese medicine composition of the present invention

[0041] a) Add 1.5 g of Acorus calamus with 8 times the amount of water, soak for 4 hours, extract the volatile oil with steam distillation for 8 hours, store the volatile oil for later use, collect the distilled aqueous solution in another device, and obtain solution 1;

[0042] b) add 10 times the amount of water to a) traditional Chinese medicine dregs, 4 g of Chinese wolfberry, 3 g of Ligustrum lucidum, and 3 g of Eclipta chinensis, decoct three times for 1 hour each time, and combine the decoctions to form solution 2;

[0043]c) Combine Solution 1 and Solution 2, filter, concentrate to a liquid medicine with a relative density of 1.08-1.10 (55° C.), spray dry to obtain a fine powder, add 0.15 g of Ginkgo biloba extract, and then add appropriate amount of sucrose and starch, Or add an appropriate amount of dextrin, make granules, dry, add volatile oil, mix well, and get ...

Embodiment 3

[0044] [embodiment 3] tablet preparation of Chinese medicine composition of the present invention

[0045] a) Add 1.5 g of Acorus calamus with 8 times the amount of water, soak for 4 hours, extract the volatile oil with steam distillation for 8 hours, store the volatile oil for later use, collect the distilled aqueous solution in another device, and obtain solution 1;

[0046] b) add 10 times the amount of water to a) traditional Chinese medicine dregs, 4 g of Chinese wolfberry, 3 g of Ligustrum lucidum, and 3 g of Eclipta chinensis, decoct three times for 1 hour each time, and combine the decoctions to form solution 2;

[0047] c) Combine Solution 1 and Solution 2, filter, concentrate to a liquid medicine with a relative density of 1.08-1.10 (55°C), spray dry to obtain a fine powder, add 0.15 g of Ginkgo biloba extract, add sucrose powder and starch, and mix Uniformly, made into granules, dried, added with volatile oil, mixed evenly, pressed into tablets, that is to say.

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PUM

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Abstract

The present invention discloses a Chinese medicine composition for effectively curing optic atrophy with obvious therapeutic effect. Said Chinese medicine composition is made up by using lyceum berry, ligustrum fruit, eclipta and ginkgo leaf extract and acorus root through a certain preparation process. Said Chinese medicine composition can be made into conventional oral dosage forms.

Description

[technical field] [0001] The invention relates to a traditional Chinese medicine composition for treating optic atrophy and a preparation method thereof, belonging to the field of traditional Chinese medicines. [Background technique] [0002] Optic atrophy belongs to the category of blue-blindness in Chinese medicine. It is a common chronic ocular fundus disease in ophthalmology. Patients experience gradual loss of vision, severe impairment of visual function, and eventually lead to blindness. It is a serious ophthalmology disease. The etiology of the disease is complex. Various diseases of the optic nerve, including inflammation, ischemia, trauma, compression, etc., can cause retinal axonal degeneration and atrophy. At present, there is no specific and effective treatment for the disease, and a large number of neurotrophic drugs and vasodilators are mainly used clinically, and the effect is not good. Chinese patents have disclosed traditional Chinese medicines for treating...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/884A61K9/08A61K9/10A61K9/14A61K9/16A61K9/20A61K9/48A61P25/00A61P27/02
Inventor 张海娟马科
Owner BEIJING INST OF OPHTHALMOLOGY