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Cerebrospinal fluid shunt having long term Anti-occlusion agent delivery

a technology of cerebrospinal fluid and shunt, which is applied in the field of cerebrospinal fluid shunt, can solve the problems of occlusion of catheter lumens, affecting the effect of csf fluid drainage, and immun response, and preventing effective drainage of csf fluid

Inactive Publication Date: 2008-04-03
MEDTRONIC PS MEDICAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0005]An occlusion resistant medical shunt, particularly a hydrocephalic shunt, is provided for implantation into a mammal. The shunt has an elongate wall structure configured as a tube having a lumen therethrough and a proximal end for receipt of bodily fluids. The bodily fluids, such as cerebrospinal fluid, flows through the shunt to a distal end for discharge of the bodily fluids. The wall structure of the shunt generally includes a biocompatible medical device material. The shunts of the present invention allow for long term delivery of one or more occlusion resistant materials to resist occlusion of the lumenal passage of the shunt.

Problems solved by technology

In either configuration, a common problem involves the immune response and / or an inflammatory response of the patient or inflammatory response to the insertion of the foreign body, i.e., the catheter, therein.
Additionally, occlusion of the catheter lumens often occur and preclude effective drainage of the CSF fluid.

Method used

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  • Cerebrospinal fluid shunt having long term Anti-occlusion agent delivery
  • Cerebrospinal fluid shunt having long term Anti-occlusion agent delivery
  • Cerebrospinal fluid shunt having long term Anti-occlusion agent delivery

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Embodiment Construction

[0012]A shunt in accordance with the invention can be used in any medical application where it is necessary to move fluid from one part of the body to another. Examples of types of shunts where the invention can be utilized include, but are not limited to, cardiac shunts, cerebral shunts, glaucoma shunts, urinary catheters, and drainage catheters for trauma or post-surgical applications.

[0013]Shunts for treatment of hydrocephalus are well known and have evolved over many decades. Typically, a hydrocephalic shunt includes tubing with a proximal end located in the brain tissue and a distal end located either within the patient at another location external to the brain or external of the patient altogether. Such shunts also typically include a valve structure designed to accommodate and / or control flow based on the intracranial pressure and the position of the patient or other factors. One example includes a valve that is configured for proper flow regulation when the patient is laying...

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Abstract

The invention includes a shunt for at least partial implantation into a patient that includes an elongated conduit having at least one lumen therethrough, that includes a proximal end for receipt of bodily fluids for flow through the shunt and a distal end for discharge of the bodily fluids from the shunt, and a long term source of at least one occlusion resistant agent, wherein said at least a portion of the at least one occlusion resistant agent can permeate through at least a portion of the elongated conduit. The invention also includes kits and systems.

Description

FIELD OF THE INVENTION[0001]This invention relates to shunts and techniques to prevent blockage or occlusion of such a shunt. One embodiment of the invention relates to a cerebrospinal fluid shunt.BACKGROUND OF THE INVENTION[0002]Hydrocephalic shunts are designed to remove excess fluid from the ventricular region of the brain to a different internal location, such as the peritoneal cavity. Alternatively, cerebral spinal fluid (CSF) shunts may have a proximal end placed into the patient's ventricular region and a distal end being connected external of the patient. In either configuration, a common problem involves the immune response and / or an inflammatory response of the patient or inflammatory response to the insertion of the foreign body, i.e., the catheter, therein. Additionally, occlusion of the catheter lumens often occur and preclude effective drainage of the CSF fluid. It is estimated that 40% of implanted hydrocephalic shunts fail within 5 years due to tissue proliferation i...

Claims

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Application Information

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IPC IPC(8): A61F2/20A61M1/00
CPCA61L31/16A61L2300/41A61L2300/416A61M2025/0019A61M25/007A61M27/006A61L2300/42
Inventor TRESCONY, PAUL V.KOULLICK, EDOUARD
Owner MEDTRONIC PS MEDICAL
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