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Polyisobutylene urethane, urea and urethane/urea copolymers and medical devices containing the same

a technology of polyisobutylene urethane and urea, which is applied in the field of polyisobutylene urethane, urea and urethane/urea copolymers and to medical devices containing the same, and can solve the problem that sibs is also highly biocompatibl

Inactive Publication Date: 2009-12-31
CARDIAC PACEMAKERS INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The present invention relates to a type of polymer called polyisobutylene urethane copolymers, which can be used to make medical devices. These copolymers have a specific structure that makes them useful in a variety of applications. The invention provides methods for making these copolymers and also includes certain medical devices that contain them. Overall, the invention provides new polymers and methods for their use in the medical device industry.

Problems solved by technology

SIBS is also highly biocompatible.

Method used

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  • Polyisobutylene urethane, urea and urethane/urea copolymers and medical devices containing the same

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Embodiment Construction

[0009]A more complete understanding of the present invention is available by reference to the following detailed description of numerous aspects and embodiments of the invention. The detailed description of the invention which follows is intended to illustrate but not limit the invention.

[0010]As is well known, “polymers” are molecules containing multiple copies (e.g., from 5 to 10 to 25 to 50 to 100 to 250 to 500 to 1000 or more copies) of one or more constitutional units, commonly referred to as monomers. As used herein, the term “monomers” may refer to free monomers and to those that have been incorporated into polymers, with the distinction being clear from the context in which the term is used.

[0011]Polymers may take on a number of configurations, which may be selected, for example, from linear, cyclic and branched configurations, among others. Branched configurations include star-shaped configurations (e.g., configurations in which three or more chains emanate from a single br...

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Abstract

The present invention pertains to polyisobutylene urethane, urea and urethane / urea copolymers, to methods of making such copolymers and to medical devices that contain such polymers. According to certain aspects of the invention, polyisobutylene urethane, urea and urethane / urea copolymers are provided, which comprise a polyisobutylene segment, an additional polymeric segment that is not a polyisobutylene segment, and a segment comprising a residue of a diisocyanate. According to other aspects of the invention, polyisobutylene urethane, urea and urethane / urea copolymers are provided, which comprise a polyisobutylene segment and end groups that comprise alkyl-, alkenyl- or alkynyl-chain-containing end groups.

Description

STATEMENT OF RELATED APPLICATION[0001]This application claims priority from U.S. provisional application 61 / 076,327 filed Jun. 27, 2008, which is incorporated herein by reference in its entirety.FIELD OF THE INVENTION[0002]The present invention relates to urethane, urea and urethane / urea copolymers and to medical devices containing the same.BACKGROUND OF THE INVENTION[0003]The use of polymeric materials in medical devices for implantation or insertion into the body of a patient is common in the practice of modern medicine. For example, polymeric materials such as silicone rubber, polyurethane, and fluoropolymers, for instance, polytetrafluoroethylene (PTFE), expanded PTFE (ePTFE) and ethylene tetrafluoroethylene (ETFE), are used as coating materials / insulation for medical leads, providing mechanical protection, electrical insulation, or both.[0004]As another example, drug eluting stents are known which have polymeric coatings over the stent to release a drug to counteract the effect...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K8/87C08F8/30A61K8/72A61N1/05A61N1/39A61N1/375
CPCA61L27/18A61L31/06C08G18/7657C08G18/6511C08G18/6204C08G18/4858C08G18/4854C08G18/4063C08G18/12C08G18/10C08L75/00C08G18/3206
Inventor DESAI, SHROJALKUMARSCHWARZ, MARLENE C.BODEN, MARKKRISHNAN, MOHANSMITH, MICHAEL C.STRICKLER, FREDERICK H.COOKE, DANIEL J.
Owner CARDIAC PACEMAKERS INC