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System and method for instrument correction using transmission efficiency

Inactive Publication Date: 2011-08-25
CHEMIMAGE TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

A disadvantage of this device is that there can be fluctuations in the transmission efficiency that depend on characteristics such as temperature, atmospheric pressure and humidity.
Due to these fluctuations, an optical instrument operating in a real-life scenario does not have a perfect or ideal performance for all wavelengths of light.

Method used

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  • System and method for instrument correction using transmission efficiency
  • System and method for instrument correction using transmission efficiency
  • System and method for instrument correction using transmission efficiency

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Embodiment Construction

Reference will now be made in detail to the preferred embodiments of the present disclosure, examples of which are illustrated in the accompanying drawings. Wherever possible, the same reference numbers will be used throughout the drawings to refer to the same or like parts.

The present disclosure provides for a system and method which hold potential for enabling the evaluation of an imperfect optical component or system in terms of its transmission or detection performance. In the case where the component or system is stable, the present disclosure contemplates that any deviations from the perfect or ideal performance may be measured and accounted for.

If a spectrum of this source were taken with an ideal instrument, the spectrum would be a flat horizontal line as a function of wavelength. In one embodiment, an ideal light source that produces the same number of photons at each wavelength may be used. When this ideal source is used with an imperfect instrument, however, the measured ...

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Abstract

A system and method for providing an instrument response correction based on transmission efficiency. Test data may be acquired at a first operating point. A look-up table may be searched to determine an instrument response correction. This look-up table may comprise a plurality of instrument response corrections, each instrument response correction corresponding to an intensity response of the sample at an operating point. The instrument response correction may then be applied to correct for environmental factors that may affect transmission efficiency. A system may comprise an illumination source, a collection optics, a tunable filter, a detector, a sensor and a control unit. The detector may detect interacted photons generated by illuminating a sample and generate test data. The sensor may be configured to sense an operating condition and transmit this information to the control unit which is configured to search a look-up table to determine the appropriate instrument response correction.

Description

BACKGROUNDSpectroscopic imaging combines digital imaging and molecular spectroscopy techniques, which can include Raman scattering, fluorescence, photoluminescence, ultraviolet, visible and infrared absorption spectroscopies. When applied to the chemical analysis of materials, spectroscopic imaging is commonly referred to as chemical imaging. Instruments for performing spectroscopic (i.e. chemical) imaging typically comprise an illumination source, image gathering optics, focal plane array imaging detectors and imaging spectrometers.In general, the sample size determines the choice of image gathering optic. For example, a microscope is typically employed for the analysis of sub micron to millimeter spatial dimension samples. For larger objects, in the range of millimeter to meter dimensions, macro lens optics are appropriate. For samples located within relatively inaccessible environments, flexible fiberscope or rigid borescopes can be employed. For very large scale objects, such as...

Claims

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Application Information

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IPC IPC(8): G06F19/00
CPCG01J3/02G01J3/0297G01N2201/1293G01N21/276G01N21/65G01J3/44
Inventor MAIER, JOHNFUHRMAN, MICHAEL
Owner CHEMIMAGE TECH