Method of monitoring depth of anesthesia and apparatus for same

a technology of depth monitoring and anesthesia, applied in the field of anesthesia, can solve the problems of prolonging the post-anesthesia recovery period and undesirable administration of anesthesia in excess

Inactive Publication Date: 2013-08-01
NEUROCHIP CORP
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It is undesirable to administer an excessive amount of anesthesia, as doing so can prolong the post-anesthesia recovery period following surgery.
It may be challenging using some known EEG-based DoA monitoring methods to identify and measure changes in the different levels of consciousness following loss of consciousness (LoC), especially during the maintenance phase of the anesthesia administration protocol.

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  • Method of monitoring depth of anesthesia and apparatus for same
  • Method of monitoring depth of anesthesia and apparatus for same
  • Method of monitoring depth of anesthesia and apparatus for same

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[0062]Digitized scalp EEG signals were sampled at 1024 Hz using disposable silver / silver-chloride electrodes, 9 mm in diameter (XLTEK, Oakville, Ontario, Canada). Electrode placement followed the international standard 10-20 system recommended by the International Federation of Societies for Electroencephalography and Clinical Neurophysiology (IFSECN), and as shown in FIG. 3. A common reference electrode was positioned between Cz and Fz. EEG signals were recorded from six (6) patients undergoing surgical procedures requiring general anesthesia and having a duration of approximately 1 hour. The patients were screened such that they were not being prescribed central nervous system (CNS) medications and did not have any diagnosed CNS pathology. EEG signals were recorded continuously just prior to and during anesthesia and surgery, and during the emergence period following anesthesia and surgery. The bispectral index (BIS™) was simultaneously recorded using a BIS™ monitor (Aspect, Mass....

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Abstract

A method of monitoring depth of anesthesia comprises generating differential EEG signals from EEG signals acquired by electrode pairs during an anesthesia protocol, processing the differential EEG signals to determine at least one signal feature and monitoring changes in the at least one signal feature to determine depth of anesthesia. The at least one signal feature comprises at least one of normalized power of the differential EEG signals acquired from at least one of the electrode pairs, and wavelet bicoherence between the differential EEG signals acquired from at least two of the electrode pairs.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This application claims the benefit of U.S. Provisional Application No. 61 / 593,188 filed on Jan. 31, 2012 entitled “METHOD OF MONITORING DEPTH OF ANESTHESIA AND APPARATUS FOR SAME”, the entire disclosure of which is incorporated herein by reference.FIELD OF THE INVENTION[0002]The present invention relates generally to anesthesia and in particular, to a method of monitoring depth of anesthesia and an apparatus for same.BACKGROUND OF THE INVENTION[0003]Anesthesia is typically used during surgery to maintain patients at a level of unconsciousness that is deep enough to enable them to undergo the surgery without pain or recall. It is undesirable to administer an excessive amount of anesthesia, as doing so can prolong the post-anesthesia recovery period following surgery. Determining the proper amount of anesthesia to administer requires a reliable measure of the depth of anesthesia (DoA) of the patient during the surgery.[0004]One approach to...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61B5/00A61B5/0478A61B5/04
CPCA61B5/726A61B5/048A61B5/4821A61B5/742A61B5/4839A61B5/0478A61B5/04012A61B5/316A61B5/374A61B5/291
Inventor BARDAKJIAN, BERJ L.KANG, EUNJI ELLEN
Owner NEUROCHIP CORP
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