Simple small animal inhalation anesthesia machine

A technology for small animals and anesthesia machines, applied in medical science, veterinary instruments, etc., can solve the problems of low morbidity and mortality of small animals, high dependence on small animal anesthesia machines, and high prices of imported anesthesia machines, and achieve good promotion. Sexuality, efficient anesthesia effect, and the effect of reducing the expenditure of funds

Active Publication Date: 2015-05-06
FUDAN UNIV
View PDF6 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The gas inhalation anesthesia technology can quickly anesthetize small animals, wake them up quickly, control the depth of anesthesia easily, and have good safety. Moreover, the morbidity and mortality of small animals are very low, and the success rate of operations is high; however, the price of imported anesthesia machines But it is very expensive, the whole set price is around 20,000 RMB
In addition, the structure of the small animal anesthesia machine volatilizer is complicated, and it is difficult to simulate and mass-produce it in China. Therefore, the current small animal anesthesia machine is highly dependent on foreign imports
At the same time, due to problems such as the manufacturing technology of imported anesthesia machines, it has brought obstacles to the domestic production of the same type of anesthesia machines
[0003] So far, there is no simple and economical small animal inhalation anesthesia device with core technology in China

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Simple small animal inhalation anesthesia machine
  • Simple small animal inhalation anesthesia machine
  • Simple small animal inhalation anesthesia machine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Such as figure 1 As shown, this simple and economical small animal inhalation anesthesia machine consists of a gas cylinder 1, a gas regulating valve 2, a three-way pipe I3, a gas flowmeter I4, a gas flowmeter II5, an isoflurane gas volatilization bottle 6, and a three-way pipe II7 , an adjustable three-way pipe 8, an anesthesia mask 9, an animal body temperature constant temperature system 10, an anesthesia induction box 11 and a gas recovery bottle 12;

[0041] The gas cylinder 1 is sequentially connected to the gas regulating valve 2 and the three-way pipe I3, one end of the three-way pipe I3 ​​is connected to the gas flowmeter I4, and the other end is connected to the gas flowmeter II5, and the gas flowmeter II5 is connected to the different The halothane gas volatilization bottle 6, the other conduit of the isoflurane gas volatilization bottle 6 is sequentially connected to the three-way pipe II7 and the adjustable three-way pipe 8, one end of the three-way pipe II...

Embodiment 2

[0049] Example 2 In vivo virus injection experiment in mouse ventricle

[0050] Such as image 3 As shown, in this example, in vivo virus injection experiments were performed on embryonic mice on day 13 of pregnancy. The pregnant mice were pre-anesthetized in an anesthesia induction box, and then the anesthetized mice were placed on a small animal thermostat (maintained at 37 ~39°C) and use a gas anesthesia hood to continuously anesthetize the surgical mouse; the total gas flow (L) should be adjusted within the range of 1L, and the gas ratio of isoflurane (L Ratio ) should be controlled within 20-30%; during the operation, closely observe the respiratory rate of the operated mice to ensure that the respiratory rate is 30-40 times / min.

[0051] The experimental results of this example show that under the above anesthesia conditions, mice can be stably and safely anesthetized for up to 3 hours. After the experiment, the anesthetized mice could wake up quickly within 5 minute...

Embodiment 3

[0052] Example 3 In vivo virus injection experiment in mouse ventricle

[0053] Such as Figure 4 As shown, in this example, an in vivo virus injection experiment was performed on the embryonic tree shrew at 34 days pregnant. The pregnant tree shrew was pre-anesthetized in the anesthesia induction box, and then the anesthetized tree shrew was placed on a small animal constant temperature pad (maintained at 37 ~39°C) and use a gas anesthesia mask to continuously anesthetize the surgical tree shrew; the total gas flow (L) should be adjusted within the range of 1.5L, and the gas ratio of isoflurane (L Ratio ) should be controlled within 20-30%; during the operation, closely observe the respiratory rate of the surgical tree shrew to ensure that the respiratory rate is 30-40 times / min.

[0054] The experimental results of this example show that under the above-mentioned anesthesia conditions, tree shrews can be stably and safely anesthetized for up to 3 hours. After the experim...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention belongs to the technical field of small animal anesthesia and relates to a simple economical small animal inhalation anesthesia machine which comprises a gas steel bottle, a gas adjusting valve, a three-way pipe I, a gas flow meter I, a gas flow meter II, an isoflurane gas volatilization bottle, a three-way pipe II, an adjustable three-way pipe, an anaesthetic mask, an animal body constant temperature system, an anesthesia induction box and a gas recycling bottle. The gas steel bottle is connected with the gas adjusting valve, the three-way pipe I, the gas flow meter I, the gas flow meter II, the isoflurane gas volatilization bottle, the three-way pipe II, the adjustable three-way pipe, the anaesthetic mask, the animal body constant temperature system, the anesthesia induction box and the gas recycling bottle in sequence. Using results show that the simple economical small animal inhalation anesthesia machine is simple and reasonable in structure, various parts are fixed and combined in a coordinating mode, small animals can be subjected to anesthesia control in short time or long time, accurate anesthesia depth is guaranteed, safety is good, after operation, the morbidity and the mortality of the small animals are low, and the operation success rate is high.

Description

technical field [0001] The invention belongs to the technical field of animal behavior experiments, and relates to an anesthesia device suitable for experimental animals, in particular to a simple and economical small animal inhalation anesthesia machine; the anesthesia machine is easy to prepare and economical in price, and can be used for gas inhalation anesthesia technology , Anesthetizing small animals safely and efficiently. Background technique [0002] The prior art discloses that the anesthesia technique for experimental small animals has been widely used in biomedicine, clinical trial research and teaching experiments. The anesthesia of the small animals is not only to reduce the pain of the animals and meet the requirements of animal welfare, but also to ensure the smooth progress of animal operations and experimental research. At present, in my country's small animal anesthesia technology, injection anesthesia is the most commonly used anesthesia method. Although...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61D7/04
CPCA61D7/04
Inventor 刘琳云
Owner FUDAN UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap