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Stimulation of subcortical brain regions using transcranial rotating permanent magnetic stimulation (TRPMS)

a technology of permanent magnetic stimulation and subcortical brain, applied in the field of medical devices, can solve the problems of low-depth stimulation and do not produce therapeutic effects, and achieve the effect of avoiding unwanted stimulation of brain structures and minimizing the strength of induced electric fields in regions outside of the region of overlap

Active Publication Date: 2021-07-01
SERAYA MEDICAL SYST LLC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This patent describes a method for using a special head mount with magnetic assemblies to stimulate or affect certain functions in the brain. The magnetic assemblies are placed on the head mount and activated to generate magnetic fluxes directed into the brain. These fluxes create an induced electric field that can stimulate neurons or modify biological processes in specific regions of the brain. The method minimizes the strength of the induced electric fields outside of the targeted region, reducing the risk of unwanted brain stimulation. Overall, this method provides a precise and targeted way to affect the brain's function.

Problems solved by technology

However, there are conditions for which shallow-depth stimulation does not produce therapeutic results.

Method used

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  • Stimulation of subcortical brain regions using transcranial rotating permanent magnetic stimulation (TRPMS)
  • Stimulation of subcortical brain regions using transcranial rotating permanent magnetic stimulation (TRPMS)
  • Stimulation of subcortical brain regions using transcranial rotating permanent magnetic stimulation (TRPMS)

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Embodiment Construction

[0019]The following description discloses a TRPMS apparatus and method for stimulating or otherwise bioelectromagnetically affecting a biological, cellular or biochemical function or structure in a targeted cortical or subcortical brain regions using a plurality of magnetic assemblies mounted on the skull of a patient. The term “bioelectromagnetically” as used herein means pertaining to the interaction between an external magnetic field and biological tissues, structures and functions. The magnetic assemblies employ rotating permanent magnets to generate time-varying magnetic fields that induce electric currents at a targeted location in the brain of the patient. TRPMS has the advantage that the spatial spread of the magnetic field and induced current is more limited in comparison to related methods such as TMS, which employs electromagnetic coils. On the other hand, TRPMS suffers from the disadvantage that magnetic field strength tends to be lower than TMS. This disadvantage is ove...

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Abstract

A method of affecting a biological, cellular or biochemical function or structure in a targeted subcortical location in a brain of a patient using a TRPMS apparatus placed on a head of the patient includes positioning two or more of a plurality of magnetic assemblies on locations of the head mount selected to stimulate the targeted subcortical location in the brain of the patient, and activating the plurality of magnetic assemblies at the selected locations to generate magnetic fluxes of a selected strength, frequency and duration directed into the brain of the patient, wherein the magnetic flux directed into the brain of the patient from each of the assemblies is operative to generate induced electric field in regions of the brain and the regions of induced electric fields generated by each of the plurality of magnetic assemblies converge in the targeted subcortical location and combine to a magnitude sufficient to affect the biological, cellular or biochemical function or structure in the targeted subcortical location.

Description

FIELD OF THE INVENTION[0001]The present invention relates to medical devices, and more particularly, relates to a system and method for neurostimulation of electrical or electrochemical activity in cortical or subcortical brain regions by application of convergent magnetic fields generated by a plurality of magnetic assemblies in a Transcranial Rotating Permanent Magnetic Stimulation (TRPMS) apparatus.BACKGROUND OF THE INVENTION[0002]Commonly-owned U.S. Pat. No. 9,456,784, entitled “Method and Apparatus for Providing Transcranial Magnetic Stimulation (TPMS) to a Patient” describes a transcranial rotating permanent magnetic stimulation apparatus (“TRPMS apparatus”) that includes replaceable magnet assemblies that can be used to generate various patterns of transcranial magnetic stimulation. FIG. 1 is a side view of an example TRPMS apparatus 5. As shown, the TRPMS apparatus 5 includes a head mount or cap 10 for positioning on a subject's head and a plurality of magnet assemblies 15 t...

Claims

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Application Information

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IPC IPC(8): A61N2/12
CPCA61N2/12A61N2/006A61N2/06
Inventor LOWIN, LEEAM
Owner SERAYA MEDICAL SYST LLC
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