The invention discloses a full-automatic aseptic production technology for blowing, filling and sealing of a water needle injection medicament. The full-automatic aseptic production technology comprises the production technology steps that firstly, raw materials are sterilized; secondly, impurity removing is conducted on the raw materials; thirdly, material melting is conducted; fourthly, filling and forming are conducted; fifthly, die opening is conducted; sixthly, punching and slitting are conducted; and seventhly checking is conducted. The materials are sterilized and disinfected in the heating step and the material melting step in the production technology, and the use risk of the materials is lowered; during forming and filling, extruding, bottle blowing, local cooling, filling, sealing and die opening are conducted, blowing, filling and sealing are combined, the bottle forming time is short, pollution to liquid medicine from microorganisms and particles in air in a sealed environment is avoided, and especially the defect of a traditional mode is overcome through the ultra-low-temperature filling technology. Meanwhile, aseptic air is used in the whole process, pollution of microorganisms in air is effectively avoided, and medicine quality is ensured greatly.