69results about How to "Avoid regulation" patented technology

The present invention relates to antibodies or fragments thereof that specifically bind FcγRIIB, particularly human FcγRIIB, with greater affinity than said antibodies or fragments thereof bind FcγRIIA, particularly human FcγRIIA. The present invention also provides the use of an anti-FcγRIIB antibody or an antigen-binding fragment thereof, as a single agent therapy for the treatment, prevention, management, or amelioration of a cancer, preferably a B-cell malignancy, particularly, B-cell chronic lymphocytic leukemia or non-Hodgkin's lymphoma, an autoimmune disorder, an inflammatory disorder, an IgE-mediated allergic disorder, or one or more symptoms thereof. The invention provides methods of enhancing the therapeutic effect of therapeutic antibodies by administering the antibodies of the invention to enhance the effector function of the therapeutic antibodies. The invention also provides methods of enhancing efficacy of a vaccine composition by administering the antibodies of the invention.

The present invention relates to antibodies or fragments thereof that specifically bind the extracellular domain of FcγRIIB, particularly human FcγRIIB, and block the Fc binding site of human FcγRIIB. The invention provides methods of treating cancer and/or regulating immune complex mediated cell activation by administering the antibodies of the invention to enhance an immune response. The invention also provides methods of breaking tolerance to an antigen by administering an antigen-antibody complex and an antibody of the invention.

The present invention relates to nucleic acid sequences and amino acid sequences which influence bone deposition, the Wnt pathway, ocular development, tooth development, and may bind to LRP. The nucleic acid sequence and polypeptides include Wise and Sost as well as a family of molecules which express a cysteine knot polypeptide. Additionally, the present invention relates to various molecular tools derived from the nucleic acids and polypeptides including vectors, transfected host cells, monochronal antibodies, Fab fragments, and methods for impacting the pathways.

The present invention relates to antibodies or fragments thereof that specifically bind FcγRIIB, particularly human FcγRIIB, with greater affinity than said antibodies or fragments thereof bind FcγRIIA, particularly human FcγRIIA. The present invention also provides the use of an anti-FcγRIIB antibody or an antigen-binding fragment thereof, as a single agent therapy for the treatment, prevention, management, or amelioration of a cancer, preferably a B-cell malignancy, particularly, B-cell chronic lymphocytic leukemia or non-Hodgkin's lymphoma, an autoimmune disorder, an inflammatory disorder, an IgE-mediated allergic disorder, or one or more symptoms thereof. The invention provides methods of enhancing the therapeutic effect of therapeutic antibodies by administering the antibodies of the invention to enhance the effector function of the therapeutic antibodies. The invention also provides methods of enhancing efficacy of a vaccine composition by administering the antibodies of the invention.

The present invention relates to antibodies or fragments thereof that specifically bind FcγRIIB, particularly human FcγRIIB, with greater affinity than said antibodies or fragments thereof bind FcγRIIA, particularly human FcγRIIA. The invention provides methods of enhancing the therapeutic effect of therapeutic antibodies by administering the antibodies of the invention to enhance the effector function of the therapeutic antibodies. The invention also provides methods of enhancing efficacy of a vaccine composition by administering the antibodies of the invention.

A tethered unmanned aerial system (UAS) is described, wherein the flight of one or more UASs may be used in connection with a water and light display.

The present invention relates to antibodies or fragments thereof that specifically bind FcγRIIB, particularly human FcγRIIB, with greater affinity than said antibodies or fragments thereof bind FcγRIIA, particularly human FcγRIIA. The invention provides methods of enhancing the therapeutic effect of therapeutic antibodies by administering the antibodies of the invention to enhance the effector function of the therapeutic antibodies. The invention also provides methods of enhancing efficacy of a vaccine composition by administering the antibodies of the invention.

The present invention relates to antibodies or fragments thereof that specifically bind FcγRIIB, particularly human FcγRIIB, with greater affinity than said antibodies or fragments thereof bind FcγRIIA, particularly human FcγRIIA. The invention provides methods of enhancing the therapeutic effect of therapeutic antibodies by administering the antibodies of the invention to enhance the effector function of the therapeutic antibodies. The invention also provides methods of enhancing efficacy of a vaccine composition by administering the antibodies of the invention.

One embodiment of the present invention provides an energy-management system for managing energy within a predominantly closed power system. During operation, the system obtains one or more control actions that control energy transitions of a plurality of components, receives transitional characteristics associated with the components, and schedules the energy transitions by generating a set of offsets. A respective offset results in a delay of at least one energy transition.

The invention proposes a generator set primary frequency modulation performance testing method for simulating grid frequency change, which comprises the following steps: arranging a frequency difference analog module and a selecting module in a generator set frequency control loop; selecting grid disturbance frequency change data ; setting the frequency difference analog module according to the data so as to enable the frequency difference analog module to simulate the frequency change during grid disturbance and to send a frequency difference signal; and allowing the selecting mode to break a frequency signal of the actual set, access the analog frequency difference signal sent by the analog module so as to test the primary frequency modulation performance of the generator set and record test process data. The method enables the primary frequency modulation of the generator set to meet the actual requirements of a grid, improves the electric energy quality of the grid, avoids the unnecessary regulation effect and saves the resources of the generator set.

System for detection and analysis of gas samples in fieldable real-time Differential Mobility Spectrometry (DMS) chemical sensor system which uses non-radioactive ion source for monitoring and detecting NOx emissions; provides reliable methods for detecting and monitoring of anthropogenic sources of NOx; also detection of NO in exhaled breath for patient health diagnosis.

Paper or cardboard machine and method for regulating a basis weight of a paper or cardboard web in the manufacturing process. The paper or cardboard machine includes at least one headbox that extends across a machine width. The at least one headbox is adapted to provide a machine-wide distribution of a material suspension onto one of a screen and between two screens. The machine also includes at least one material suspension supply coupled to the at least one headbox and adapted to supply a material suspension to the at least one headbox. The at least one material suspension supply has at least one concentration. At least one first control loop is provided that includes at least one actuator being adapted to adjust the at least one concentration of the at least one material suspension supply, at least one detector for determining a basis weight of a finished web, at least one supply being adapted to modify the at least one concentration of the at least one material suspension supply, and at least one device that adjusts the at least one actuator. In this manner, the at least one concentration of the at least one material suspension supply is adjusted. At least one second control loop is provided that is adapted to regulate the concentration of the material suspension supply. The method includes determining a basis weight at an end of the manufacturing process, calculating a deviation of the determined basis weight from a predetermined target value, adjusting a concentration of a material suspension supplied to a headbox via a first control loop such that the calculated deviation is corrected, one of directly and indirectly measuring a basis weight of a resulting web in a region upstream, with regard to a web travel direction, a drying section, and supplying a signal related to the measured basis weight to a second control loop.

A surround sound audio processing system includes a source that supplies a first signal for producing a first sound impression and a second signal for producing a second sound impression. A processing unit modifies the first signal and the second signal to produce a third sound impression of a virtual source, and provides first and second modified signals indicative thereof. The processing unit modifies the first signal and the second signal relative to each other such that the first and second modified signals have a phase shift of between 170° to 190°.

A method may include storing information in a supply mesh. The supply mesh may include two or more value links. The method may include determining that a first value link of the two or more value links fulfills a value link condition of a second value link. The method may include providing a transaction proposal to the first value link. The transaction proposal may include an amount of private currency. The method may include receiving, from the first value link, a transaction acceptance to the transaction proposal. The method may include transferring the amount of private currency from the second value link to the first value link. The method may include confirming completion of a transaction between the first value link and the second value link. The transaction may be based on the transaction proposal. Other methods and systems are also disclosed.

The invention, which belongs to the new energy material and device field, especially relates to a back contact structure of a cadmium telluride thin-film solar cell, a solar cell, a cell assembly, and a preparation method. According to the technical scheme, the back contact structure that is arranged between a cadmium telluride absorption layer and a back electrode layer is a mixture layer with molybdenum nitride and molybdenum oxide; and the structure is expressed by (1-A) molybdenum nitride-A molybdenum nitride, wherein the A is larger than 0 and is less than 1. The work function of MoOy is high and the conductivity of MoNx is good; and thus, on the basis of combination of the MoOy material and the MoNx material, the back contact material can have advantages of the two kinds of materials.

The invention relates to a data security interaction method based on host characteristic confusion, and relates to a method for realizing data interaction through exposure of different host fingerprint information carried by an interaction data packet to the opposite party according to a predefined rule in an open network environment by employing a home-terminal host fingerprint confusion pool bytwo communication parties. According to the method, a host fingerprint communication byte substitution list is pre-stored in two communication terminals, a plurality of heterogeneous containers are generated to dynamically construct the host fingering confusion pool, an information source triggers the corresponding heterogeneous container in the confusion pool to generate the data packet carryingspecific host fingerprint information for reply according to a data request, and an information sink analyzes and replies the fingerprint information and obtains final data by employing the substitution list. According to the method, interaction data is hidden in various standard and ordinary protocol host fingerprint characteristics, any service information is not represented, and data security interaction of two communication parties is guaranteed.

In an MRAM having main and sub-structures, selecting transistors are arranged so as to meet the arrangement order of main word lines, sub-word lines and the selecting transistors. The selecting transistor is driven to cause a snap back phenomenon to occur. As a result, data can be written to a memory cell using a substrate current, not a channel current. Moreover, a data may be written into a selected memory cell by discharge the charge which is charged in the main and sub word lines corresponding to the memory cell.