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Medicine for treating cardio-cerebrovascular disease

A technology for cardiovascular and cerebrovascular diseases and medicines, applied in the fields of migraine, treatment of cardiovascular and cerebrovascular diseases, women's climacteric syndrome medicines, and diabetes, which can solve problems such as side effects and can not be used to treat diabetes

Active Publication Date: 2008-06-04
西藏诺迪康药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It is a good way to treat chest obstruction (coronary heart disease, angina pectoris) by nourishing and strengthening the body, promoting blood circulation and removing blood stasis. At present, there are many drugs for treating cardiovascular and cerebrovascular diseases, but most of them have side effects, and they cannot be used to treat diabetes and women's menopause. Syndrome etc.

Method used

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  • Medicine for treating cardio-cerebrovascular disease
  • Medicine for treating cardio-cerebrovascular disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] In Example 1, the capsule-type drug is made by cutting 2000 grams of Rhodiola rosea rhizomes selected, washed and dried into thick slices of 1 to 2 cm, and decocted at an altitude of 3600 to 3800 meters and at a temperature of 0°C to 15°C. Boil twice, add 8 times and 6 times the amount of rhizome of Rhodiola rosea in the first and second times respectively, decoct for 90 minutes for the first time, and 60 minutes for the second time (the boiling temperature of each item is 92-93 ℃), combined decoction, filtered with a ceramic membrane (0.5 μm), the filtrate was concentrated to 40 ℃ temperature and relative density was 1.25~1.30, spray-dried with a high-speed centrifugal spray dryer to obtain the Rhodiola rosea extract. The extract of Rhodiola rosea and medicinal starch are mixed according to the weight ratio of 10:4, and 75% (volume ratio) ethanol is used as a wetting agent, and granulated by automatic wet method or (fluidized granulation), After being dried to a water ...

Embodiment 2

[0049] The tablet drug of Example 2 is prepared from the extract of Rhodia rhododendron and starch in Example 1. The weight ratio of Rhodiola rosea extract and medicinal starch is 202:78 and the ingredients are mixed evenly, wet or fluidized granulation, and the qualified granules are compressed with a high-speed tablet machine (tablet pressure 16KN, machine speed 100,000 tablet / hour), and then carry out film-coating with the film-coating powder produced by Chengdu Hengtai Macromolecule Film Material Factory to obtain tablets.

Embodiment 3

[0051] The granule medicine in Example 3 is formulated with the Rhodiola rosea extract, dextrin, and powdered sugar in Example 1. According to the weight ratio of Rhodiola rosea extract, dextrin, and powdered sugar 60:200:740, the ingredients are mixed evenly, with an appropriate amount of 70% (volume ratio) medicinal ethanol as a wetting agent, stirred with water, and then wet or fluidized Granulate, sieve, and dry until the moisture content is below 4%.

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Abstract

The present invention provides a Chinese medicine for effectively curing the diseases of angiocardiopathy, cerebrovascular disease, migraine, diabetes and menopausal syndrome of women. Said Chinese medicine is made up by using rhodiola sacra extract as main raw material and adding medicinal auxiliary material through a certain preparation process. Besides, said invention also provides the concrete steps of said preparation process.

Description

Technical field: [0001] The invention relates to medicines for treating cardiovascular and cerebrovascular diseases, migraine, diabetes and climacteric syndrome. Background technique: [0002] Chest obstruction (coronary heart disease, angina pectoris), symptoms include chest pain, chest tightness, palpitations, shortness of breath, dizziness, fatigue, insomnia and dreaminess, etc. Coronary heart disease has many similar records in ancient Chinese medical literature, such as "Su Wen Visceral Qi Method" In Shi Lun Pian, there are: "Heart disease patients have pain in the chest, hypochondriac fullness, hypochondriac pain, eagle back pain between shoulder blades, and internal pain in both arms", which is actually a description of the pain site of angina pectoris. "Lingshu · Que disease" says: "The heart hurts, the hands are blue and knotted, the heartache is so severe, and it will die soon", which shows that the severity of angina pectoris and its prognosis have been recognized...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/41A61K9/48A61K9/28A61K9/16A61P9/10A61P25/06A61P25/12
Inventor 周裕程
Owner 西藏诺迪康药业股份有限公司
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