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Impedance tomography apparatus based on microneedle electrodes and micro-traumatic measuring method thereof

A technology of tomography and electrical impedance, which is applied in the field of medical microsystems and biomedical detection, can solve problems such as inaccurate measurement results, low image resolution, and poor calculation accuracy, so as to achieve good signal directivity and avoid microneedling Difficult to enter and reduce the effect of error

Inactive Publication Date: 2009-01-14
TSINGHUA UNIV
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Problems solved by technology

[0010] The purpose of the present invention is to aim at the deficiencies and defects of the prior art, combine microneedle technology in MEMS with bioelectrical impedance imaging technology, and provide an electrical impedance tomography device based on microneedle electrodes and its minimally invasive Measurement method to solve the problems of poor calculation accuracy, low image resolution and inaccurate measurement results in the existing electrical impedance imaging technology due to the inability to avoid the high impedance layer of the skin

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  • Impedance tomography apparatus based on microneedle electrodes and micro-traumatic measuring method thereof
  • Impedance tomography apparatus based on microneedle electrodes and micro-traumatic measuring method thereof
  • Impedance tomography apparatus based on microneedle electrodes and micro-traumatic measuring method thereof

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Embodiment Construction

[0029] The specific structure, measurement principle, process and implementation of the present invention will be further described below in conjunction with the accompanying drawings.

[0030] The electric impedance tomography instrument and its measurement method based on microneedle electrodes provided by the present invention are based on the medical characteristics of the skin surface, and can cross the high-impedance stratum corneum (thickness 10-15 μm) of the outermost layer of human skin, Reach the epidermal layer composed of living cells, which is conductive and permeable, and does not include nerves and blood vessels. It is equivalent to electrolyte (thickness 50-100 μm), and it will not cause pain and bleeding when piercing, so as to achieve superior minimally invasiveness Conductive function.

[0031] figure 1It is a structural principle block diagram of an electrical impedance tomography instrument based on microneedle electrodes. The imager includes a microneedl...

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Abstract

The invention relates to a resistance chromatography imager based on micro electrode, and relative micro-cut measurement, wherein it uses micro electrode to span the horny layer with high resistance; it can replace traditional surface electrode, to be used as current activator and sensor to sense voltage signal; the measured signal via magnification and filter is input into PC to be processed and displayed via gray diagram or colorful diagram, to represent the resistance distribution. The invention can reduce the effect of skin resistance in current activation and voltage signal collection, with high signal-noise ratio and reduced error, to improve the calculation accuracy and image resolution.

Description

technical field [0001] The invention relates to an electrical impedance tomography (EIT) device and measurement technology, in particular to an electrical impedance tomography instrument based on a microneedle electrode and a minimally invasive measurement method thereof, belonging to medical microsystem and biomedical detection technology field. Background technique [0002] Electrical impedance tomography (electrical impedance tomography, EIT) is based on the different electrical characteristic parameters (such as resistivity, permittivity) of the internal tissue of the object, by applying a safe excitation current or voltage to the surface, and simultaneously measuring the voltage or voltage on the surface of the object. The current signal is used to obtain the distribution of the internal electrical parameters of the object, and then reconstruct an image reflecting the internal structure of the object. This is of great significance to the study of the internal electrica...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/053
Inventor 刘冉刘静陈颀潇王广志丁辉
Owner TSINGHUA UNIV
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