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Compound panoxatriol saponin with physiological activity and its preparation and use

A panaxatriol saponin, physiological activity technology, applied in the direction of organic active ingredients, medical preparations containing active ingredients, pharmaceutical formulations, etc. , Promote brain function, improve the effect of brain oxygen supply and blood supply

Inactive Publication Date: 2010-03-24
玉溪维和香格喜玛生物技术有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are some research reports on the effective extraction parts of each single, but there is no compound research identical to the patent application of the present invention

Method used

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  • Compound panoxatriol saponin with physiological activity and its preparation and use
  • Compound panoxatriol saponin with physiological activity and its preparation and use
  • Compound panoxatriol saponin with physiological activity and its preparation and use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1: compound panaxatriol type saponin granule

[0035] formula:

[0036] PTG (Rg 1 =55.4%): 155g

[0037] Ginkgo Biloba Extract 100g

[0038] Theanine 70g

[0039] Vitamin B 1 5g

[0040] Vitamin B 2 4g

[0041] Vitamin B 6 4g

[0042] Sucrose 2500g

[0043] Dextrin 300g

[0044] Cyclodextrin 55g

[0045] Proper amount of ethanol

[0046] Granulate according to the common granulation method, and pack into 1000 bags (about 3.1g per bag). Take one bag each time, 1-2 times a day.

Embodiment 2

[0047] Embodiment 2, compound panaxatriol type saponin capsule

[0048] formula:

[0049] PTG (Rg 1 =65.1%): 29g

[0050] Ginkgo Biloba Extract 24g

[0051] Theanine 25g

[0052] Vitamin B 1 1.7g

[0053] Vitamin B 2 1.6g

[0054] Vitamin B 61.5g

[0055] soybean oil 400g

[0056] The raw materials are mixed, ultra-fine (more than 2000 mesh), and the rubber is prepared according to the preparation method of ordinary capsules. Preparation of liquid medicine: add the ultra-fine compound medicine into the solvent matrix, fully stir, dissolve, filter, degas, and send it to the tank above the filling machine for use; at the same time, prepare the thermal insulation gelatin tank above the soft capsule filling machine The gelatin solution used for the rubber in the medium is ready for use; under the conditions of 100,000 grades, 21°C-25°C, RH%: 39-41%, start the rotary molding machine to press the pills, wash the soft capsules made, and put them...

Embodiment 3

[0057] Embodiment 3: compound panaxatriol type saponin dripping pill

[0058] formula:

[0059] PTG (Rg 1 =65.1%): 32g

[0060] Ginkgo Biloba Extract 18g

[0061] Theanine 12g

[0062] PEG-6000 300g

[0063] It is prepared according to the preparation method of ordinary drop pills, that is, the active ingredients of the drug are mixed, added to the matrix PEG-6000, heated and melted into a liquid state, dropped into the liquid paraffin condensate under heat preservation, and controlled at a certain speed to make it solidify into a round shape. spherical. Get the drop pills, measure the content of each pill, take Rg each time 1 The meter should be 20mg to determine the dosage.

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PUM

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Abstract

The compound panoxatriol saponin with physiological activity contains panoxatriol saponin, gingko extractive, theanine and supplementary material is prepared into various preparations. The compound panoxatriol saponin can treat cerebral atherosclerosis, senile dementia, etc. by means of the functions of strengthening the activity of cerebral cell and cerebral nerve cell, improving brain's oxygen and blood supplying state, etc.

Description

Technical field [0001] The invention relates to a compound panaxatriol saponin with physiological activity, its preparation and application. Background technique [0002] Ginseng (Korean ginseng), American ginseng and Panax notoginseng (also known as Panax notoginseng, Tianqi, southern ginseng) are all plants of the genus Panax of Araliaceae. Their roots, leaves, flowers, etc. have medicinal value, mainly containing ginsenosides and other substances. According to research data, it is confirmed that ginsenosides, American ginseng saponins and Panax notoginseng saponins extracted from various plants are mainly composed of Rb 1 Mainly panaxadiol saponins and Rg 1 Mainly composed of panaxatriol-type saponins. Diol-type saponins and triol-type saponins have both similarities and differences, and they even have opposite effects on the nervous system. The two have similar effects in improving the hemodynamics of blood circulation, reducing blood viscosity, and lowering blood li...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7048A61K9/00A61P9/10A61P25/00
Inventor 杨兆祥艾黎
Owner 玉溪维和香格喜玛生物技术有限责任公司
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