A medicinal composition for treating oral ulcer and its preparation method

A technology for oral ulcers and compositions, which is applied in the field of pharmaceutical compositions for the treatment of oral ulcers, can solve problems such as affecting the appearance, numbness of the tongue, difficulty in preparing oral preparations, etc., and achieves fast healing of ulcers, convenient storage, and significant curative effect Effect

Active Publication Date: 2007-08-01
四川自豪时代药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] The powder is used locally on the ulcer surface, and it is easy to disperse and take effect quickly. However, because it treats the special part of the mouth, the medicine in the oral cavity is easily affected by various factors, so that the medicine cannot stay on the wound for a long time, and When the powder flows in the mouth, it will stick to the teeth, the corners of the mouth, etc., which will affect the appearance, and it is inconvenient to use

Method used

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  • A medicinal composition for treating oral ulcer and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1 preparation of medicine buccal tablet of the present invention

[0034] Weigh the raw materials according to the following ratio:

[0035] Qingdai 0.3Kg Catechin 0.3Kg Borneol 0.3Kg

[0036] Sorbitol 1.16Kg Sucrose 1.16Kg Dextrin 2.49Kg

[0037] Neotame 0.0026Kg Menthol 0.029Kg Magnesium Stearate 0.058Kg

[0038] The production method is as follows:

[0039]First, crush Qingdai and catechu through a 100-mesh sieve, and grind borneol through a 100-mesh sieve; weigh the fine powder of Qingdai and catechin, add sorbitol, sucrose powder, dextrin, neotame, mix well, and make granules, 60°C Dry for 6 hours, granulate, and pass through a 20-mesh sieve; spray with ethanol solution containing menthol, and seal for 2 hours; add borneol fine powder and magnesium stearate, mix well, and press into tablets to obtain buccal tablets.

Embodiment 2

[0040] Embodiment 2 preparation of medicine buccal tablet of the present invention

[0041] Weigh the raw materials according to the following ratio:

[0042] Qingdai 0.1Kg Catechin 0.1Kg Borneol 0.1Kg

[0043] Sorbitol 1.0Kg Sucrose 1.0Kg Dextrin 2.0Kg

[0044] Neotame 0.002Kg Menthol 0.02Kg Magnesium Stearate 0.05Kg

[0045] The production method is as follows:

[0046] First, crush Qingdai and catechu through a 100-mesh sieve, and grind borneol through a 100-mesh sieve; weigh the fine powder of Qingdai and catechin, add sorbitol, sucrose powder, dextrin, neotame, mix well, and make granules, 60°C Dry for 6 hours, granulate, and pass through a 20-mesh sieve; spray with ethanol solution containing menthol, and seal for 2 hours; add borneol fine powder and magnesium stearate, mix well, and press into tablets to obtain buccal tablets.

Embodiment 3

[0047] Embodiment 3 pharmaceutical buccal tablet preparation of the present invention

[0048] Weigh the raw materials according to the following ratio:

[0049] Qingdai 0.5Kg Catechin 0.5Kg Borneol 0.5Kg

[0050] Sorbitol 1.5Kg Sucrose 1.5Kg Dextrin 2.5Kg

[0051] Neotame 0.003Kg Menthol 0.05Kg Magnesium Stearate 0.05Kg

[0052] The production method is as follows:

[0053] First, crush Qingdai and catechu through a 100-mesh sieve, and grind borneol through a 100-mesh sieve; weigh the fine powder of Qingdai and catechin, add sorbitol, sucrose powder, dextrin, neotame, mix well, and make granules, 60°C Dry for 6 hours, granulate, and pass through a 20-mesh sieve; spray with ethanol solution containing menthol, and seal for 2 hours; add borneol fine powder and magnesium stearate, mix well, and press into tablets to obtain buccal tablets.

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Abstract

The invention discloses a pharmaceutical composition for treating ulcerative stomatitis, which is prepared from raw materials including natural indigo, black catechu, boneol, cane sugar, Nutrasweet, menthol and auxiliary materials. The invention also provides the process for preparing the pharmaceutical composition.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating oral ulcers, in particular to a buccal preparation for treating oral ulcers prepared from traditional Chinese medicines. Background technique [0002] Recurrent oral ulceration is the most common disease in oral mucosal diseases. Prevalence rate occupies the first place of oral mucosa disease. Sircus surveyed 1587 people, the prevalence rate was 20%; Axell surveyed 30118 people, the prevalence rate was 17.7%; Beijing Medical University Dental Hospital investigated 9463 people, the prevalence rate was 18.3%. It can be seen that oral ulcer patients are a very large group. The etiology of recurrent oral ulcers is complex and still unclear. It may be related to factors such as viral infection, bacterial infection, endocrine disorder, and immune dysfunction. [0003] At present, there are many medicines for the treatment of oral ulcers in China, but the preparations with definite curative...

Claims

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Application Information

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IPC IPC(8): A61K36/70A61K36/48A61K9/12A61K9/20A61K47/40A61K47/18A61P1/04A61K31/045
Inventor 何宇新谢雷谢凯
Owner 四川自豪时代药业有限公司
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